Effects of sugar-sweetened beverage intake on the development of type 2 diabetes mellitus in subjects with impaired glucose tolerance: the Mihama Diabetes Prevention Study

• Material Type: 博士論文
• Title: Effects of sugar-sweetened beverage intake on the development of type 2 diabetes mellitus in subjects with impaired glucose tolerance: the Mihama Diabetes Prevention Study
• Author/Editor: TESHIMA, Nobuko
• Author Heading: TESHIMA, Nobuko
• Publication, Distribution, etc.: 三重大学
• Publication Date: 2015-07-15
• Publication Date (W3CDTF): 2015-07-15
• Degree grantor/type: 三重大学
• Date Granted: 2015-07-15
• Date Granted (W3CDTF): 2015-07-15
• Dissertation Number: 乙医学第984号
• Degree Type: 博士(医学)
• Conferring No. (Dissertation): 乙医学第984号
• Text Language Code: eng
• Alias of Author: テシマ, ノブコ; 手島, 信子
• Subject Heading: type 2 diabetes; sugar intake; sweetened beverage; nutritional behavior; cohort study
• Target Audience: 一般
• Note (General): application/pdf; In Japan, the incidence of type 2 diabetes mellitus (T2DM) is increasing for several reasons, including increased consumption of sugar-sweetened beverages (SSBs). However, whether SSBs cause T2DM by excess of energy production resulting in obesity remains unclear. Therefore, the present study was designed to evaluate the effects of SSB intake on the development of T2DM in subjects with impaired glucose tolerance (IGT). Ninety-three subjects (30 males and 63 females) with IGT aged 40-69 y and residing in the Mihama district (southern Mie Prefecture, Japan) were included in the study. The mean observational period was 3.6 y. All subjects underwent the 75-g oral glucose tolerance test (OGTT)and completed a lifestyle questionnaire survey related to SSB intake. OGTT results and SSB intake were evaluated before and after the observational period. In addition, the correlation between SSB intake and development of T2DM was investigated. Of the 93 subjects, 20(21.5%) developed T2DM (T2DM group) and demonstrated a significantly high SSB intake compared with the group that did not develop the disease (non-T2DM group). The odds ratio for the incidence of T2DM based on SSB intake was 3.26 (95% confidence interval, 1.17-90.6). The body mass index (BMI; kg/m2) and the homeostasis model assessment for insulin resistance (HOMA-R) values was significantly higher in the T2DM group than in the non-T2DM group, while the insulinogenic indices were significantly lower in the former than in the latter group. The sum of insulin secretion levels during OGTT was not significantly different between groups. SSB intake correlated with the predisposition for developing T2DM, possibly by influencing body weight, insulin resistance, and the ability of the pancreatic beta cells to effectively compensate for the insulin resistance.; 本文/Division of Dietary Service.Mie University Hospital; 6p
• DOI: info:doi/10.3177/jnsv.61.14; https://doi.org/info:doi/10.3177/jnsv.61.14
• Persistent ID (NDL): info:ndljp/pid/11526697; https://dl.ndl.go.jp/pid/11526697
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2020-08-11T22:41:34+09:00
• Date Created (W3CDTF): 2020-07-29
• Format (IMT): application/pdf
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Periodical Title (URI): http://hdl.handle.net/10076/00019136; https://mie-u.repo.nii.ac.jp/records/13518
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp

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2023-12-15 再収集