Health-related quality of life in Japanese patients with prostate cancer following proton beam therapy: an institutional cohort study 5

• 資料種別: 博士論文
• ISSN: 1465-3621
• タイトル: Health-related quality of life in Japanese patients with prostate cancer following proton beam therapy: an institutional cohort study
• 巻次・部編番号: 50 5
• 著者・編者: 松川, 京子
• 著者標目: 松川, 京子
• 出版事項: Oxford University Press
• 出版年月日等: 2020-09-02; 50 5
• 出版年（W3CDTF）: 2020-09-02
• 並列タイトル等: 日本における前立腺癌患者の陽子線治療による健康関連QOL：単施設コホート研究
• タイトル（掲載誌）: Japanese Journal of Clinical Oncology
• 授与機関名: Nagasaki University (長崎大学)
• 授与年月日: 2020-09-02
• 授与年月日（W3CDTF）: 2020-09-02
• 報告番号: 甲医歯薬第1281号
• 学位: 博士(医学)
• 博論授与番号: 甲医歯薬第1281号
• 本文の言語コード: eng
• 件名標目: prostate cancer; proton beam therapy; health-related quality of life; Japanese patients
• 対象利用者: 一般
• 一般注記: Objective: Many treatment options have guaranteed long-term survival in patients with localized prostate cancer and health-related quality of life has become a greater concern for those patients. The purpose of this study was to reveal the health-related quality of life after proton beam therapy and to clarify the differences from other treatment modalities for prostate cancer. Methods: Between January 2011 and April 2016, 583 patients were enrolled in the study and health-related quality of life outcomes using the Expanded Prostate Cancer Index Composite questionnaire were evaluated and compared with previous research targeted at Japanese patients. Results: We found a significant decrease in the least square mean scores for urinary and bowel domains excluding the incontinence subscale after proton beam therapy (P < 0.0001) and recovery at a year following treatment. The scores for sexual function in patients without androgen deprivation therapy decreased each year after proton beam therapy (P < 0.0001). The scores for hormones in patients without androgen deprivation therapy remained high and those of patients with androgen deprivation therapy were lower before treatment but were comparable to those of non-androgen deprivation therapy patients at 2 years post-treatment. We found that the impact of radiotherapy including proton beam therapy on urinary condition and sexual function was lower than that of surgery. Conclusions: For the first time in Japan, we investigated health-related quality of life using Expanded Prostate Cancer Index Composite questionnaires in patients with prostate cancer after proton beam therapy and compared it with other treatment modalities.; 長崎大学学位論文 学位記番号:博(医歯薬)甲第1281号 学位授与年月日:令和2年9月2日; Author: Kyoko Matsukawa, Takeshi Arimura, Makiko Orita, Hisayoshi Kondo, Ikuko Chuman, Takashi Ogino, Yasuyuki Taira, Takashi Kudo, Noboru Takamura; Citation: Japanese Journal of Clinical Oncology, 50(5), pp.519?527; 2020; identifier:Nagasaki University (長崎大学), 博士(医学) (2020-09-02)
• DOI: info:doi/10.1093/jjco/hyaa027; https://doi.org/info:doi/10.1093/jjco/hyaa027
• 国立国会図書館永続的識別子: info:ndljp/pid/11552088; https://dl.ndl.go.jp/pid/11552088
• コレクション（共通）: 障害者向け資料
• コレクション（障害者向け資料：レベル1）: テキストデータ
• コレクション（個別）: 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• 収集根拠: 博士論文（自動収集）
• 受理日（W3CDTF）: 2020-10-06T21:18:06+09:00
• 作成日（W3CDTF）: 2020-12-16
• 記録形式（IMT）: PDF
• オンライン閲覧公開範囲: 国立国会図書館内限定公開
• デジタル化資料送信: 図書館・個人送信対象外
• 遠隔複写可否（NDL）: 可
• 関連情報（URI）: http://hdl.handle.net/10069/40352
• 掲載誌（URI）: http://hdl.handle.net/10069/40292
• 連携機関・データベース: 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp

目次

2021-03-07 再収集