並列タイトル等β-TCP顆粒と自家骨顆粒を組み合わせた再生骨における骨再生のメカニズム解明
一般注記We examined the amount and maturity of collagen as a parameter for bone quality in the graft material transplanted into a rat skull bone defect model. Male SD rats were used to generate an experimental animal model of skull defects. The obtained autologous bone granules and β-TCP granules were mixed at a ratio of 1:1 to prepare a graft material that combines autologous bone with β-TCP granules. At 8 weeks after transplantation, the β-TCP+ autologous bone and the autologous bone groups showed BV/TV values, measured based on CT image analysis, significantly different from those in the β-TCP and control groups. The β-TCP+ autologous bone group exhibited the ability to form blood vessels into the graft material for a longer period of time after transplantation compared to that in the autologous bone group, as well as the elevated production of collagen into β-TCP granules during the bone formation process compared to that in the β-TCP group.
2020年度
コレクション（個別）国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文
受理日（W3CDTF）2022-02-06T04:33:19+09:00
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