Elucidation of the Mechanism of Bone Regeneration When a Mixture of β-TCP and Autologous Bone Granules are Transplanted

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Elucidation of the Mechanism of Bone Regeneration When a Mixture of β-TCP and Autologous Bone Granules are Transplanted

Persistent ID (NDL): info:ndljp/pid/12071389

Material type: 博士論文

Author: 辰村, 正泰

Publisher: -

Publication date: 2021-03-05

Material Format: Digital

Capacity, size, etc.: -

Name of awarding university/degree: 大阪歯科大学,博士（歯学）

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Note (General)：: We examined the amount and maturity of collagen as a parameter for bone quality in the graft material transplanted into a rat skull bone defect model....

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Material Type: 博士論文
Title: Elucidation of the Mechanism of Bone Regeneration When a Mixture of β-TCP and Autologous Bone Granules are Transplanted
Author/Editor: 辰村, 正泰
Author Heading: 辰村, 正泰
Publication Date: 2021-03-05
Publication Date (W3CDTF): 2021-03-05
Alternative Title: β-TCP顆粒と自家骨顆粒を組み合わせた再生骨における骨再生のメカニズム解明
Degree grantor/type: 大阪歯科大学
Date Granted: 2021-03-05
Date Granted (W3CDTF): 2021-03-05
Dissertation Number: 甲第908号
Degree Type: 博士（歯学）
Conferring No. (Dissertation): 甲第908号
Text Language Code: eng
Subject Heading: autologous bone graft
β-TCP granules
micro-CT
picrosirius red staining
col-lagen
vWF immunostaining
Target Audience: 一般
Note (General): We examined the amount and maturity of collagen as a parameter for bone quality in the graft material transplanted into a rat skull bone defect model. Male SD rats were used to generate an experimental animal model of skull defects. The obtained autologous bone granules and β-TCP granules were mixed at a ratio of 1:1 to prepare a graft material that combines autologous bone with β-TCP granules.　At 8 weeks after transplantation, the β-TCP+ autologous bone and the autologous bone groups showed BV/TV values, measured based on CT image analysis, significantly different from those in the β-TCP and control groups. The β-TCP+ autologous bone group exhibited the ability to form blood vessels into the graft material for a longer period of time after transplantation compared to that in the autologous bone group, as well as the elevated production of collagen into β-TCP granules during the bone formation process compared to that in the β-TCP group.
2020年度
Persistent ID (NDL): info:ndljp/pid/12071389
https://dl.ndl.go.jp/pid/12071389
Collection: 障害者向け資料
Collection (Materials For Handicapped People:1): テキストデータ
Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文
https://dl.ndl.go.jp/collections/A00014
Acquisition Basis: 博士論文（自動収集）
Date Accepted (W3CDTF): 2022-02-06T04:33:19+09:00
Date Created (W3CDTF): 2021-04-23
Format (IMT): application/pdf
Access Restrictions: 国立国会図書館内限定公開
Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
Availability of remote photoduplication service: 可
Periodical Title (URI): http://id.nii.ac.jp/1392/00000275/
Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション
https://dl.ndl.go.jp