Antimicrobial Effect of Titanium Hydroxyapatite in Denture Base Resin

• 資料種別: 博士論文
• タイトル: Antimicrobial Effect of Titanium Hydroxyapatite in Denture Base Resin
• 著者・編者: 佐藤, 航
• 著者標目: 佐藤, 航
• 出版年月日等: 2019-03-08
• 出版年（W3CDTF）: 2019-03-08
• 並列タイトル等: 義歯床用レジンに含まれたチタンアパタイトの抗菌効果
• 授与機関名: 大阪歯科大学
• 授与年月日: 2019-03-08
• 授与年月日（W3CDTF）: 2019-03-08
• 報告番号: 甲第833号
• 学位: 博士（歯学）
• 博論授与番号: 甲第833号
• 本文の言語コード: eng
• 件名標目: titanium hydroxyapatite｜photocatalyst｜bacterial biofilms｜antimicrobial effect｜denture
• 対象利用者: 一般
• 一般注記: In the current study, we investigated the antimicrobial effect of titanium hydroxyapatite (TiHA), a photo-oxidizing organic material, in denture base resin on single-species biofilms formed by laboratory bacteria and on multispecies biofilms formed by bacteria from the human saliva. Although TiHA reportedly restricts the growth of planktonic bacteria upon ultraviolet A (UVA) irradiation, the antimicrobial effect of TiHA on bacterial biofilms remains to be elucidated. Resin specimens were prepared by adding TiHA to polymethyl methacrylate-based, denture base resin. The specimens were incubated with biofilm-forming Streptococcus sanguinis, Actinomyces naeslundii, Staphylococcus aureus, Escherichia coli, or bacteria from the human saliva obtained from volunteers. After UVA irradiation, the colony-forming units (CFUs) from the biofilms formed on the specimens were determined. CFU numbers for S. sanguinis, A. naeslundii, and S. aureus that formed biofilms on TiHA-containing specimens were significantly lower than those formed on specimens without TiHA. TiHA did not reduce the CFUs of biofilm-forming E. coli. In all cases, CFU numbers in the biofilms formed on TiHA-containing specimens by the salivary bacteria were significantly reduced. In addition, neither a 56 h UVA irradiation nor a 28 d soaking in water diminished the antibacterial effect of TiHA. TiHA in denture base resin exerts an antimicrobial effect on single-species bacterial biofilms and biofilms formed by a wide variety of bacteria from human saliva.; 2018年度; 機関リポジトリ記載の権利情報: CC BY-NC-ND
• 国立国会図書館永続的識別子: info:ndljp/pid/12071554; https://dl.ndl.go.jp/pid/12071554
• コレクション（共通）: 障害者向け資料
• コレクション（障害者向け資料：レベル1）: テキストデータ
• コレクション（個別）: 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• 収集根拠: 博士論文（自動収集）
• 受理日（W3CDTF）: 2022-02-06T04:33:19+09:00
• 記録形式（IMT）: application/pdf
• オンライン閲覧公開範囲: 国立国会図書館内限定公開
• デジタル化資料送信: 図書館・個人送信対象外
• 遠隔複写可否（NDL）: 可
• 掲載誌（URI）: http://id.nii.ac.jp/1392/00000186/
• 連携機関・データベース: 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp