Antimicrobial Effect of Titanium Hydroxyapatite in Denture Base Resin
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- Material Type
- 博士論文
- Author/Editor
- 佐藤, 航
- Author Heading
- Publication Date
- 2019-03-08
- Publication Date (W3CDTF)
- 2019-03-08
- Alternative Title
- 義歯床用レジンに含まれたチタンアパタイトの抗菌効果
- Degree Grantor
- 大阪歯科大学
- Date Granted
- 2019-03-08
- Date Granted (W3CDTF)
- 2019-03-08
- Dissertation Number
- 甲第833号
- Degree Type
- 博士（歯学）
- Conferring No. (Dissertation)
- 甲第833号
- Text Language Code
- eng
- Subject Heading
- Target Audience
- 一般
- Note (General)
- In the current study, we investigated the antimicrobial effect of titanium hydroxyapatite (TiHA), a photo-oxidizing organic material, in denture base resin on single-species biofilms formed by laboratory bacteria and on multispecies biofilms formed by bacteria from the human saliva. Although TiHA reportedly restricts the growth of planktonic bacteria upon ultraviolet A (UVA) irradiation, the antimicrobial effect of TiHA on bacterial biofilms remains to be elucidated. Resin specimens were prepared by adding TiHA to polymethyl methacrylate-based, denture base resin. The specimens were incubated with biofilm-forming Streptococcus sanguinis, Actinomyces naeslundii, Staphylococcus aureus, Escherichia coli, or bacteria from the human saliva obtained from volunteers. After UVA irradiation, the colony-forming units (CFUs) from the biofilms formed on the specimens were determined. CFU numbers for S. sanguinis, A. naeslundii, and S. aureus that formed biofilms on TiHA-containing specimens were significantly lower than those formed on specimens without TiHA. TiHA did not reduce the CFUs of biofilm-forming E. coli. In all cases, CFU numbers in the biofilms formed on TiHA-containing specimens by the salivary bacteria were significantly reduced. In addition, neither a 56 h UVA irradiation nor a 28 d soaking in water diminished the antibacterial effect of TiHA. TiHA in denture base resin exerts an antimicrobial effect on single-species bacterial biofilms and biofilms formed by a wide variety of bacteria from human saliva.2018年度機関リポジトリ記載の権利情報: CC BY-NC-ND
- Persistent ID (NDL)
- info:ndljp/pid/12071554
- Collection
- Collection (Materials For Handicapped People:1)
- Collection (particular)
- 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文
- Acquisition Basis
- 博士論文（自動収集）
- Date Accepted (W3CDTF)
- 2022-02-06T04:33:19+09:00
- Format (IMT)
- application/pdf
- Access Restrictions
- 国立国会図書館内限定公開
- Service for the Digitized Contents Transmission Service
- 図書館・個人送信対象外
- Availability of remote photoduplication service
- 可
- Periodical Title (URI)
- Data Provider (Database)
- 国立国会図書館 : 国立国会図書館デジタルコレクション