手術前の患者における深部静脈血栓症の診断のための新しい検査前確率スコア

• 資料種別: 博士論文
• タイトル: 手術前の患者における深部静脈血栓症の診断のための新しい検査前確率スコア
• 著者・編者: 濱元, 裕喜
• 著者標目: 濱元, 裕喜
• 出版事項: Elsevier
• 出版年月日等: 2022-03-11
• 出版年（W3CDTF）: 2022-03-11
• 並列タイトル等: A new pre-test probability score for diagnosis of deep vein thrombosis in patients before surgery
• 授与機関名: 鹿児島大学
• 授与年月日: 2022-03-11
• 授与年月日（W3CDTF）: 2022-03-11
• 報告番号: 甲総研第652号
• 学位: 博士(医学)
• 本文の言語コード: eng
• 件名標目: Before surgery; D-dimer; Deep vein thrombosis; Kagoshima-DVT score; Pre-test probability score; Whole leg ultrasonography
• 対象利用者: 一般
• 一般注記: 出版タイプ： VoR; 博士論文全文, 博士論文要旨, 最終試験結果の要旨, 論文審査の要旨; Background: Venous thromboembolism is a serious perioperative complication. We developed a new pre-test probability score for predicting deep vein thrombosis (DVT) before surgery.Methods: Whole leg ultrasonography was performed on 973 inpatients and outpatients with suspected DVT based on a preoperative D-dimer cut-off value of ≥ 1 μg/ml. We allocated two-thirds (n = 651) of the study participants to a derivation cohort and one-third (n = 322) to a validation cohort. The pre-test probability model was developed from the derivation cohort data.Results: The pre-test probability model for DVT assigned 2 points to D-dimer ≥ 1.5 μg/mL and 1 point each to age ≥ 60 years, female sex, ongoing glucocorticoid therapy, prolonged immobility, and cancer with high risk of DVT. The area under the curve of the pre-test probability score was 0.72 and 0.70 in the derivation and validation cohorts, respectively. The rates of DVT according to pre-test probability scores in the derivation and validation cohorts were 7% and 6% in the low (score = 0-2), 23% and 22% in the intermediate (score = 3-4), and 47% and 50% in the high probability group (score ≥ 5), respectively (p < 0.0001).Conclusions: The pre-test probability score (Kagoshima-DVT score) was helpful in detecting preoperative DVT in both inpatients and outpatients. We identified low probability group to reduce whole-leg ultrasonography and high probability group to detect more DVT before surgery.Yuki Hamamoto, Akihiro Tokushige, Yuasa Toshinori, Yoshiyuki Ikeda, Yoshihisa Horizoe, Hisayo Yasuda, Takuro Kubozono, Mitsuru OhishiA new pre-test probability score for diagnosis of deep vein thrombosis in patients before surgeryJournal of Cardiology 79 (2022) 664–670
• 国立国会図書館永続的識別子: info:ndljp/pid/12769212; https://dl.ndl.go.jp/pid/12769212
• コレクション（共通）: 障害者向け資料
• コレクション（障害者向け資料：レベル1）: テキストデータ
• コレクション（個別）: 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• 収集根拠: 博士論文（自動収集）
• 記録形式（IMT）: application/pdf
• オンライン閲覧公開範囲: 国立国会図書館内限定公開
• デジタル化資料送信: 図書館・個人送信対象外
• 遠隔複写可否（NDL）: 可
• 掲載誌（URI）: http://hdl.handle.net/10232/00031991
• 連携機関・データベース: 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp

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