手術前の患者における深部静脈血栓症の診断のための新しい検査前確率スコア

• Material Type: 博士論文
• Title: 手術前の患者における深部静脈血栓症の診断のための新しい検査前確率スコア
• Author/Editor: 濱元, 裕喜
• Author Heading: 濱元, 裕喜
• Publication, Distribution, etc.: Elsevier
• Publication Date: 2022-03-11
• Publication Date (W3CDTF): 2022-03-11
• Alternative Title: A new pre-test probability score for diagnosis of deep vein thrombosis in patients before surgery
• Degree Grantor: 鹿児島大学
• Date Granted: 2022-03-11
• Date Granted (W3CDTF): 2022-03-11
• Dissertation Number: 甲総研第652号
• Degree Type: 博士(医学)
• Text Language Code: eng
• Subject Heading: Before surgery; D-dimer; Deep vein thrombosis; Kagoshima-DVT score; Pre-test probability score; Whole leg ultrasonography
• Target Audience: 一般
• Note (General): 出版タイプ： VoR; 博士論文全文, 博士論文要旨, 最終試験結果の要旨, 論文審査の要旨; Background: Venous thromboembolism is a serious perioperative complication. We developed a new pre-test probability score for predicting deep vein thrombosis (DVT) before surgery.Methods: Whole leg ultrasonography was performed on 973 inpatients and outpatients with suspected DVT based on a preoperative D-dimer cut-off value of ≥ 1 μg/ml. We allocated two-thirds (n = 651) of the study participants to a derivation cohort and one-third (n = 322) to a validation cohort. The pre-test probability model was developed from the derivation cohort data.Results: The pre-test probability model for DVT assigned 2 points to D-dimer ≥ 1.5 μg/mL and 1 point each to age ≥ 60 years, female sex, ongoing glucocorticoid therapy, prolonged immobility, and cancer with high risk of DVT. The area under the curve of the pre-test probability score was 0.72 and 0.70 in the derivation and validation cohorts, respectively. The rates of DVT according to pre-test probability scores in the derivation and validation cohorts were 7% and 6% in the low (score = 0-2), 23% and 22% in the intermediate (score = 3-4), and 47% and 50% in the high probability group (score ≥ 5), respectively (p < 0.0001).Conclusions: The pre-test probability score (Kagoshima-DVT score) was helpful in detecting preoperative DVT in both inpatients and outpatients. We identified low probability group to reduce whole-leg ultrasonography and high probability group to detect more DVT before surgery.Yuki Hamamoto, Akihiro Tokushige, Yuasa Toshinori, Yoshiyuki Ikeda, Yoshihisa Horizoe, Hisayo Yasuda, Takuro Kubozono, Mitsuru OhishiA new pre-test probability score for diagnosis of deep vein thrombosis in patients before surgeryJournal of Cardiology 79 (2022) 664–670
• Persistent ID (NDL): info:ndljp/pid/12769212; https://dl.ndl.go.jp/pid/12769212
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Format (IMT): application/pdf
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Periodical Title (URI): http://hdl.handle.net/10232/00031991
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp

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