Glycative stress and skeletal muscle dysfunctions : as an inducer of "Exercise-Resistance"

• 資料種別: 記事
• タイトル: Glycative stress and skeletal muscle dysfunctions : as an inducer of "Exercise-Resistance"
• 著者・編者: Tatsuro Egawa; Takeshi Ogawa; Takumi Yokokawa
• 出版事項: 日本 : 糖化ストレス研究会
• 出版年月日等: 2022-12-31
• 出版年（W3CDTF）: 2022-12-31
• 並列タイトル等: 糖化ストレスによる骨格筋機能低下 : 運動抵抗性誘導因子としての着目
• タイトル（掲載誌）: Glycative stress research
• 巻号年月日等（掲載誌）: 9(4)
• 掲載巻: 9(4)
• ISSN（掲載誌）: 2188-3610
• ISSN-L（掲載誌）: 2188-3610
• 本文の言語コード: eng; jpn
• DOI: 10.24659/gsr.9.4_199; https://doi.org/10.24659/gsr.9.4_199
• 国立国会図書館永続的識別子: info:ndljp/pid/13120789; https://dl.ndl.go.jp/pid/13120789
• コレクション（共通）: 障害者向け資料
• コレクション（障害者向け資料：レベル1）: テキストデータ
• コレクション（個別）: 国立国会図書館デジタルコレクション > 電子書籍・電子雑誌 > その他; https://dl.ndl.go.jp/collections/B00035
• 収集根拠: オンライン資料収集制度
• 受理日（W3CDTF）: 2023-12-08T11:19:22+09:00
• 保存日（W3CDTF）: 2023-05-20
• 記録形式（IMT）: application/pdf
• オンライン閲覧公開範囲: 国立国会図書館内限定公開
• デジタル化資料送信: 図書館・個人送信対象外
• 遠隔複写可否（NDL）: 可
• 掲載誌（URI）: https://www.toukastress.jp/webj/
• 掲載誌（国立国会図書館永続的識別子）: info:ndljp/pid/13120786; https://dl.ndl.go.jp/pid/13120786
• 連携機関・データベース: 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp

• コレクション（個別）: 国立国会図書館デジタルコレクション > 電子書籍・電子雑誌 > その他; https://dl.ndl.go.jp/collections/B00035
• オンライン閲覧公開範囲: 国立国会図書館内限定公開
• デジタル化資料送信: 図書館・個人送信対象外
• 遠隔複写可否（NDL）: 可
• 所蔵機関: 国立国会図書館
• 請求記号: Z63-D541
• 関連情報（URI）: https://dl.ndl.go.jp/info:ndljp/pid/13120789
• 関連情報（国立国会図書館永続的識別子）: info:ndljp/pid/13120789; https://dl.ndl.go.jp/info:ndljp/pid/13120789
• 連携機関・データベース: 国立国会図書館 : 国立国会図書館雑誌記事索引; https://ndlsearch.ndl.go.jp
• 書誌ID（NDLBibID）: 032834821; http://id.ndl.go.jp/bib/032834821
• 整理区分コード: 632

• 要約等: Skeletal muscle, the largest tissue in the body, is often overlooked for its role as a locomotor organ, however over the past few decades it has been revealed that it also has an important role as a metabolic organ. In recent years, its role as an endocrine organ that controls the homeostatic functions of organs throughout the body mediated by myokine secretion has come under close scrutiny. Skeletal muscle is indispensable for our daily life activities, and in order to maintain its function, it is necessary to understand the factors that deteriorate muscle function and establish a countermeasure. Glycative stress has recently received attention as a factor that impairs skeletal muscle function. Accumulation of advanced glycation end products (AGEs) in skeletal muscle impairs contractile function and myogenic potential. Furthermore, AGEs in the blood elicit inflammatory signals through binding to RAGE (Receptor for AGEs) expressed on muscle cells, resulting in muscle proteolysis. Habitual exercise is important to mitigate the negative effects of such glycative stress on skeletal muscle. On the other hand, it is known that the beneficial effects of exercise vary among individuals. The state in which the effects of exercise are difficult to obtain is called "exercise-resistance," and we hypothesize that glycative stress may be one of the causes of exercise-resistance. In this paper, we will discuss the possibility of glycative stress as an inducer of exercise resistance and summarize its impacts on skeletal muscle.
• DOI: 10.24659/gsr.9.4_199
• オンライン閲覧公開範囲: インターネット公開
• 連携機関・データベース: 科学技術振興機構 : J-STAGE; http://www.jstage.jst.go.jp

• 要約等: Skeletal muscle, the largest tissue in the body, is often overlooked for its role as a locomotor organ, however over the past few decades it has been revealed that it also has an important role as a metabolic organ. In recent years, its role as an endocrine organ that controls the homeostatic functions of organs throughout the body mediated by myokine secretion has come under close scrutiny. Skeletal muscle is indispensable for our daily life activities, and in order to maintain its function, it is necessary to understand the factors that deteriorate muscle function and establish a countermeasure. Glycative stress has recently received attention as a factor that impairs skeletal muscle function. Accumulation of advanced glycation end products (AGEs) in skeletal muscle impairs contractile function and myogenic potential. Furthermore, AGEs in the blood elicit inflammatory signals through binding to RAGE (Receptor for AGEs) expressed on muscle cells, resulting in muscle proteolysis. Habitual exercise is important to mitigate the negative effects of such glycative stress on skeletal muscle. On the other hand, it is known that the beneficial effects of exercise vary among individuals. The state in which the effects of exercise are difficult to obtain is called "exercise-resistance," and we hypothesize that glycative stress may be one of the causes of exercise-resistance. In this paper, we will discuss the possibility of glycative stress as an inducer of exercise resistance and summarize its impacts on skeletal muscle.
• DOI: 10.24659/gsr.9.4_199; https://doi.org/10.24659/gsr.9.4_199
• オンライン閲覧公開範囲: インターネット公開
• 関連情報（URI）: http://hdl.handle.net/2433/278940; http://id.ndl.go.jp/bib/032834821; https://ndlsearch.ndl.go.jp/books/R000000004-I032834821; https://dl.ndl.go.jp/pid/13120789; http://id.ndl.go.jp/digimeta/13120789; https://search.jamas.or.jp/link/ui/2024086129
• 連携機関・データベース: 国立情報学研究所 : CiNii Research; https://cir.nii.ac.jp/
• 提供元機関・データベース: Japan Link Center; https://japanlinkcenter.org/top; 学術機関リポジトリデータベース; https://irdb.nii.ac.jp; 雑誌記事索引データベース; https://ndlsearch.ndl.go.jp; 科学研究費助成事業データベース; https://kaken.nii.ac.jp/ja
• 書誌ID（NDLBibID）: 032834821; http://id.ndl.go.jp/bib/032834821; 13120789; http://id.ndl.go.jp/bib/13120789