Verification of improvement of periorbital wrinkles by using Asakado Skin Care
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DOI[10.24659/gsr.10.1_27]のデータに遷移します
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- 資料種別
- 記事
- 著者・編者
- Yoshikazu YoneiMasayuki Yagi
- 出版事項
- 出版年月日等
- 2023-03-31
- 出版年（W3CDTF）
- 2023-03-31
- 並列タイトル等
- Asakado浅花堂スキンケア使用による目尻のシワ改善効果の検証腸脳力を活かした質の高い健康長寿実現のアプローチ
- タイトル（掲載誌）
- Glycative stress research
- 巻号年月日等（掲載誌）
- 10(1)
- 掲載巻
- 10(1)
- ISSN（掲載誌）
- 2188-3610
- ISSN-L（掲載誌）
- 2188-3610
- 本文の言語コード
- engjpn
- DOI
- 10.24659/gsr.10.1_27
- 国立国会図書館永続的識別子
- info:ndljp/pid/13120796
- コレクション（共通）
- コレクション（障害者向け資料：レベル1）
- コレクション（個別）
- 国立国会図書館デジタルコレクション > 電子書籍・電子雑誌 > その他
- 収集根拠
- オンライン資料収集制度
- 受理日（W3CDTF）
- 2023-12-08T11:19:23+09:00
- 保存日（W3CDTF）
- 2023-05-20
- 記録形式（IMT）
- application/pdf
- オンライン閲覧公開範囲
- 国立国会図書館内限定公開
- デジタル化資料送信
- 図書館・個人送信対象外
- 遠隔複写可否（NDL）
- 可
- 掲載誌（URI）
- 掲載誌（国立国会図書館永続的識別子）
- info:ndljp/pid/13120792
- 連携機関・データベース
- 国立国会図書館 : 国立国会図書館デジタルコレクション
- コレクション（個別）
- 国立国会図書館デジタルコレクション > 電子書籍・電子雑誌 > その他
- オンライン閲覧公開範囲
- 国立国会図書館内限定公開
- デジタル化資料送信
- 図書館・個人送信対象外
- 遠隔複写可否（NDL）
- 可
- 所蔵機関
- 国立国会図書館
- 請求記号
- Z63-D541
- 関連情報（国立国会図書館永続的識別子）
- info:ndljp/pid/13120796
- 連携機関・データベース
- 国立国会図書館 : 国立国会図書館雑誌記事索引
- 書誌ID（NDLBibID）
- 033430116
- 整理区分コード
- 632
- 要約等
- The present study conducted a trial for a skin application of a test cosmetic product with 34 healthy women aged between 35 to 55 years of age (43.4 ± 0.6) who satisfied the classification of 1, 2, and 3 in the standards for the wrinkle grade assessment in accordance with "Guidelines for Evaluation of Cosmetic Functions". In a half face method for 8 weeks, the test cosmetic sample was applied to one lateral periorbital lines of a face (applied side) twice a day and no treatment was applied over the other periorbital lines (non-applied side). The test product was a skin-care cosmetic that contained diverse constituents such as <i>Ceratonia siliqua</i> L. fruit extract, <i>Polygonum tinctorium</i> leaf/stem extract, and ribosomal constituents. In test results after 8 weeks for the primary endpoint of grade assessments of periorbital wrinkles, the grade on the applied side indicated significant improvements through a visual assessment during a medical examination and a visual assessment of observing case photographic images by medical specialists. However, results of the primary endpoint on the non-applied side also indicated significant improvements. There was no significant difference between two sides. Replica analysis examining periorbital wrinkles did not suggest any significant changes between on applied or non-applied side as well as between before and after test product application. Secondary endpoint of skin viscoelasticity (R2) significantly improved on the applied and non-applied sides after 8 weeks. There was no significant difference of changes in quantity. In the process of the trial, no adverse event was reported and the safety of the test product was confirmed. We conducted a further investigation to explore possibilities that diverse functional ingredients contained in this product were absorbed through percutaneous absorption with an assistance of ribosomal constituents, and exerted effects toward the other side of the face. To verify this hypothesis, further examinations are required to confirm blood concentrations of active components after tests.
- DOI
- 10.24659/gsr.10.1_27
- オンライン閲覧公開範囲
- インターネット公開
- 連携機関・データベース
- 科学技術振興機構 : J-STAGE
- 要約等
- The present study conducted a trial for a skin application of a test cosmetic product with 34 healthy women aged between 35 to 55 years of age (43.4 ± 0.6) who satisfied the classification of 1, 2, and 3 in the standards for the wrinkle grade assessment in accordance with "Guidelines for Evaluation of Cosmetic Functions". In a half face method for 8 weeks, the test cosmetic sample was applied to one lateral periorbital lines of a face (applied side) twice a day and no treatment was applied over the other periorbital lines (non-applied side). The test product was a skin-care cosmetic that contained diverse constituents such as <i>Ceratonia siliqua</i> L. fruit extract, <i>Polygonum tinctorium</i> leaf/stem extract, and ribosomal constituents. In test results after 8 weeks for the primary endpoint of grade assessments of periorbital wrinkles, the grade on the applied side indicated significant improvements through a visual assessment during a medical examination and a visual assessment of observing case photographic images by medical specialists. However, results of the primary endpoint on the non-applied side also indicated significant improvements. There was no significant difference between two sides. Replica analysis examining periorbital wrinkles did not suggest any significant changes between on applied or non-applied side as well as between before and after test product application. Secondary endpoint of skin viscoelasticity (R2) significantly improved on the applied and non-applied sides after 8 weeks. There was no significant difference of changes in quantity. In the process of the trial, no adverse event was reported and the safety of the test product was confirmed. We conducted a further investigation to explore possibilities that diverse functional ingredients contained in this product were absorbed through percutaneous absorption with an assistance of ribosomal constituents, and exerted effects toward the other side of the face. To verify this hypothesis, further examinations are required to confirm blood concentrations of active components after tests.
- DOI
- 10.24659/gsr.10.1_27
- 関連情報（URI）
- 連携機関・データベース
- 国立情報学研究所 : CiNii Research
- 提供元機関・データベース
- Japan Link Center雑誌記事索引データベース雑誌記事索引データベース
- 書誌ID（NDLBibID）
- 03343011613120796