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目次Preface : in honor of Professor Satoshi Omura on the occasion of his 70th birthday Satoshi Õmura, Ph.D. Publications list 3,4,5,6-tetrasubstituted 2-pyridone synthesis via nucleophilic addition of active methine compounds to dialkynyl imines directed to the synthesis of (-)-A58365A Total synthesis of (–)-pramanicin Rapid 'SAR' via click chemistry : an alkyne-bearing spiramycin is fused with diverse azides to yield new triazole-antibacterial candidates Synthesis of tulipalin b and 1-O-methyl-6-tuliposide B Stereoselective synthesis of trans-3a-aryloctahydroindoles using cyclization of N-vinylic α-(methylthio)acetamides Acridone heterocycles as fluorescent sensors for anions Direct observation of esr spectra of bicyclic nine-membered enediynes at ambient temperature Convergent synthesis of the CDEF ring fragment of yessotoxin via α-cyano ethers 4-aryl-2-quinolones via a domino Heck reaction/cyclization process Synthesis of cyclic polyglycerols Oxidative cyclization of isodityrosine tripeptides : optimized condition and application of electrochemically generated thallium(Ⅲ) ion Reaction of 2H-cyclohepta[b]furan-2-ones with pyridinium salts of trifluoromethanesulfonic anhydride 5-acyl-2h-pyran-2-ones in the Schmidt reaction : migration of the pyran-2-one ring Starter unit specificity of the asukamycin "upper" chain polyketide synthase and the branched-chain fatty acid synthase of Streptomyces nodosus subsp. asukaensis Exploring the synthesis of masked phosphoramido 6-vinylcytidine derivatives as building blocks for cross-linking oligonucleotides Reactions of 8-(triphenylphosphoimino)quinoline with aryl aldehydes and aryl isocyanates : formation of 2-aryl-4H-imidazo[4,5,1-ij]quinolines and related systems Synthesis of new pyrrolidine derivatives as inhibitors of α-mannosidase and of the growth of human glioblastoma cells Novel chiral synthetic path to indolizidine and quinolizidine alkaloids by means of a samarium diiodide-promoted reductive carbon-nitrogen cleavage reaction : synthesis of (+)-(8R, 8aR)-perhydro-8-indolizidinol and (-)-deoxynupharidine Syntheses of ulocladol Three new phlegmarine-type lycopodium alkaloids, lycoposerramines-X, -Y and -Z, having a nitrone residue, from Lycopodium serratum Further structure-activity relationships of the myxobacterial antibiotics cystothiazoles Anthocyanins from the rhizome of Raphanus sativus, and change in the composition during maturation Chaxine A, an osteoclast-forming suppressing substance, from the mushroom Agrocybe chaxingu 1-hydroxyyohimbine and its derivatives : new potent α₂-blockers for the treatment of erectile dysfunction A new useful conversion method of naltrexone to 14-deoxynaltrexone Synthesis of functionalized phospholane oxides and phosphorinane oxides from 1,4- and 1,5-di-O-mesyloxy compounds Arabidopside F, a new oxylipin from Arabidopsis thaliana Addition reaction of o-toluamides with chiral auxiliary derived from 2-amino-1,3-propanediols to imines Synthesis, oxygen activation, and DNA-cleaving property of a histidine-pyridine-histidine ligand Transformations of 4-hydroxy-5,6,7,8-tetrafluorocoumarin derivatives with monoamines Efficient synthesis of optically active 4,5-dihydroxy-2,3,4,5-tetrahydro-1H-1-benzazepine derivatives utilizing lipase-catalyzed transesterification Strained 1-azabicyclo[1.1.0]butanes in the synthesis of azetidinethiocarboxylate derivatives Synthesis and properties of novel bis(1,3-benzodithiolium)-type dications containing a biaryl unit : new redox systems undergoing reversible structural changes by electron transfer Inhibition of NF-kappa B activation by 9-methylstreptimidone isolated from Streptomyces Catalytic, stereoselective glycosylation : spiroketalization of 3,4,5-tri-o-benzyl-β-d-fructopyranose generating di-D-fructopyranose- 1,2’:2,1’-dianhydride Synthesis and biological activities of biscarboxymethyl lipid a analogues Hetero Diels-Alder type reactions between Danishefsky’s dienes in the presence of lewis base catalysts : an efficient method for the synthesis of substituted 2,3-dihydropyran-4-ones Oxidative cyclization reaction of dibenzylbutanolides with combined utilization of synthetic chemistry and biotechnological methods Synthesis of the 37-epi-HIJ ring system of adriatoxin Four new kabiramides from the Thai sponge, Pachastrissa nux Synthesis of the hemiacetal pheromone of the spined citrus bug Biprorulus bibax utilizing an iridium catalyzed oxidative lactonization Tryptophan 4-aminocinnamamides from a myxomycete Fuligo aurea Lycovatine A, a C₁₆N-type quaternary alkaloid from Lycopodium clavatum var. robustum Synthesis of 2-hydroxy-1,2,3,4-tetrahydroquinoline derivatives by a cyclocondensation reaction New furanocoumarins isolated from the roots of Ferulago isaurica pesmen growing in Turkey Synthesis and biological activities of sugar analogs of mycalamide A Short step synthesis of natural 2-arylquinolones based on iridium-catalyzed three-component coupling quinoline synthesis Design and synthesis of telomestatin derivatives and their inhibitory activity of telomerase Synthesis of N1,N3-free pyrimidine bridged polycyclic compounds via photo-Diels-Alder reaction of N,N-diacetyl-5-fluorouracil with naphthalenes Neurotrophic sesterterpenes isolated from a marine sponge, Spongia sp. Enantioselective intramolecular C-H amidation of sulfamate esters catalyzed by chiral dirhodium(Ⅱ) carboxylates Norepinephrine reuptake inhibitors for depression, ADHD and other neuropsychiatric disorders Synthesis of partially fluorinated heterocycles from 4,4-bis(trifluoromethyl) substituted hetero-1,3-dienes via C-F bond activation and their application as trifluoromethyl substituted building blocks Fluorine-containing 2-functionalized 1,3-dicarbonyl compounds for heterocyclic synthesis
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目次Endo-selective asymmetric inverse electron-demand 1,3-dipolar cycloaddition reaction of nitrones Regioselective N- and o-alkylation of 3H-[1,2,3]triazolo[4,5-d]pyrimidine-5,7(4H,6H)-diones (8-azaxanthines) and transformation of 3-alkyl derivatives into 1-alkyl isomers An efficient method for the synthesis of 3-mercapto-1-(1,3-thiazolin-2-yl)azetidine useful for the pendant moiety of oral carbapenem, L-084 4-acyl-5-hydroxy-1-phenyl-3-trifluoromethylpyrazoles : synthesis and NMR spectral investigations Efficient Michael addition of indoles using bismuthyl perchlorate as catalyst 3-benzoyl-4-hydroxyisochromen-1-one derivatives, their synthesis and synthetic application Highly stereoselective formation of 1,3-dioxolanes by photocatalytic ring opening reactions of α-epoxyketones in acetone solution using 1-benzyl-2,4,6-triphenylpyridinium tetrafluoroborate (NBTPT) Synthesis of 4-trifluoromethylpyrimido[4,5-c]pyridazine-5,7-diones from uracils A novel two step synthesis of 3,4-dihydro-4-oxo-5H-pyrano[2,3-d]pyrimidines Bromination of dimethyl 1-substituted indole-2,3-dicarboxylates Accelerated synthesis of novel 1,2,4-triazolo[3,4-b][1,3,4]thiadiazepines under microwave irradiation Cutc mediated coupling of 6,7-disubstituted benzothiazoles Two new macrocyclic compounds from the stems of Clematis armandii Synthesis of 3-DPA lactone via tandem cyclization reaction of acetonide protected methyl 4,5-dihydroxy-2-chloroglycidate Synthetic studies of bioactive quinoxalinones : a facile approach to potent euglycemic and hypolipidemic agents New synthesis of 3-aryl-2,5-dihydrofurans A new pyrrolidine-2,4-dione derivative, vermelhotin, isolated from unidentified fungus IFM 52672 Three new isochromans from the mycelial culture of a Cylindrocarpon fungus Microwave-assisted synthesis of pyrazoles by 1,3-dipolar cycloaddition of diazo compounds to acetylene derivatives New dioxomorpholine derivatives, javanicunine A and B, from Eupenicillium javanicum Solvent-free reaction using phosphonium salts : chlorination of hydroxyheteroaromatics and dehydration of primary amides
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目次TCT (2,4,6-trichloro-1,3,5-triazine) promoted single-step syntheis of 4,6-diarylpyrimidin-2(1H)-ones under microwave irradiation A facile and convenient synthesis of 1H-isoindole-1,3(2H)-diones The ideal synthetic method aimed at the leads for an α₂-blocker, an inhibitor of blood platelet aggregation, and an anti-osteoporosis agent Preferred conformations of diastereomeric N-acyl-1-naphthylalanylprolinamides and related dipeptides and their fluorescence quenching by chiral amines Sulfur-mediated synthesis of substituted tetrahydrofurans : application to the synthesis of goniofufurone Synthesis and characterization of 1,3,4-oxadiazoles triazolopyridinone and carbazole as the potential bluish-green electroluminescent materials for the single layer device Synthesis and properties of some dihydrotetrazolo[5,1-c][1,2,4]triazines One-pot synthesis of 2-imino-1,3-selenazolidines by reaction of isoselenocyanates with propargylamine Stilbenoids with one epoxy group from Cotylelobium lanceolatum Synthesis and structural study of semicarbazone-containing 1,4-dihydropyridine Ionic liquid in organic synthesis : the Pictet-Spengler reaction Phosphoric acid-on-silica gel : a green catalyst for the synthesis of symmetrical bis(indolyl)alkanes A simple KHSO₄ promoted synthesis of 2-arylsubstituted benzimidazoles by oxidative condensation of aldehydes with o-phenylenediamine Indium-mediated reductive cyclization of 2-nitrochalcones to quinolines Hetero-Diels-Alder reaction of ethyl 2-nitrosoacrylate and cyclohexadienes, and bromine induced diene isomerization Two new indoloquinazoline alkaloids from the unripe fruits of Evodia rutaecarpa An acylated cyanidin 3-rutinoside-7-glucoside with p-hydroxybenzoic acid from the red-purple flowers of Campanula medium A computational study on stabilities of dihydropterins Synthesis of benzo[2,1-b:3,4-b’]dithiophene-4,5-dione derivatives Synthesis of substituted aminoquinolines as useful intermediates for preparation of aromatic N-tricyclic systems 1,2,4-triazolo[1,5-a][1,3,5]triazines (5-azapurines) : synthesis and biological activity
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目次Reductive formation of 1,5-benzothiazepines Synthesis of N1-unsubstituted 5-alkynylcytosine and derivatives thereof Enantioselective microbial hydrolysis of disubstituted cyclic carbonates Hypervalent organoantimony compound 12-aryltetrahydrodibenz[c,f][1,5]azastibocine : new transmetallating agent for palladium-catalyzed arylation of organic halides Synthesis and basic optical properties of new π-conjugated thiophene-pyridine co-oligomers An efficient and convenient method for synthesis of 1-substituted imidazoles Novel azolinium/rhodium system catalyzed addition of arylboronic acids to aldehydes Solid-state photocycloaddition of 6,6’-dimethyl-4,4’-polymethylenedioxy-di-2-pyrones to benzophenone Synthesis of 4-(dimethylamino)pyridinium-substituted pyrazine, pyridazine, 1,3,5-triazine, purine, and imidazole The first synthesis of (-)-plakolide A Regio- and exo-π-facial selective 1,3-dipolar cycloaddition of α-(3-pyridyl)-N-phenylnitrone to norbornadiene : activation of a π-bond of norbornadiene and control of regiochemistry of nitrone cycloaddition by nitrone addition to the other double bond Enzyme inhibition studies of oxindole alkaloids from Isatis costata Synthesis of tetrahydrofurfurylamines related to muscarine Polyphosphoric acid-induced construction of quinazolinone skeleton from 1-(3,4-dimethoxyphenyl)-3-phenylurea and carboxylic acids Asymmetric synthesis of (-)-verrucosapyrone A by biocatalyst and determination of its absolute configuration A new butenolide-type fungal pigment from the mushroom Pulveroboletus ravenelii Structural characterization of isomeric methyl 2-(2-oxo-3-indolyl)acetate and methyl 1-(2-oxo-4-quinolyl)formate Supramolecular species bearing quaternary azaaromatic moieties
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目次An efficient synthesis of (±)-myxopyronin b via versatile pyridone intermediates Synthesis and fluorescence of 6-(4-dimethylaminophenyl)- and 6-[2-(4-N,N-disubstituted aminophenyl)vinyl]-4-methylthio-2-oxo-2H-pyran-3-carbonitriles in solution and in the solid states Synthetic utilization of polynitroaromatic compounds 4 : synthesis of nitro-free 4,6-disubstituted-3-aminobenzothiophene derivatives based on 2,4,6-trinitrobenzamide Facile synthesis of 2-arylpyrroles from 4-oxo-butanoic acids and their use in the preparation of bis(pyrrolyl)methanes Bioactive saponins and glycosides ⅩⅩⅥ : new triterpene saponins, theasaponins E₁₀,E₁₁,E₁₂,E₁₃, and G₂, from the seeds of tea plant (Camellia sinensis) Expeditious synthesis of 2-aryl substituted imidazolines and imidazoles Heterocycles [h]fused onto 4-oxoquinolines. part Ⅰ : synthesis of 6-oxo-6,9-dihydro[1,2,5]oxadiazolo[3,4-h]quinoline-7-carboxylic acid N-oxide Concise synthesis of 3-arylpiperidines An convenient method for the synthesis of 7,8-dimethoxy-3-hydroxyquinolin-2(1H)-one and its tautomer conformation study Synthesis of selenosemicarbazides and 1,2,4-triazoles Synthesis and extraction properties of new fused benzocrown-heterocycle ligands for alkali and alkaline earth metal cations Microwave-promoted aromatization of 1,3,5-trisubstituted 4,5-dihydro-1H-pyrazoles by calcium hypochlorite under solvent-free conditions Water-tolerant and reusable catalyst for the one-pot synthesis of dihydropyrimidin-2(1H)-ones under solvent-free conditions Regioselective synthesis of the novel N₄-substituted pyrazolo[4,5-e][1,2,4]thiadiazines as potent HIV-1 NNRTIs Palladium-catalyzed asymmetric allylic alkylation using chiral pyridyl-hydrazone ligands Evoninoate sesquiterpene alkaloids from the stem of Celastrus paniculatus Synthesis and structural properties of cyclophanes containing thiophene rings in the side-chain New lignans from Kadsura coccinea and their nitric oxide inhibitory activities Synthesis of 1,3-selenazetidines and 4H-1,3,5-oxadiazines using acyl isoselenocyanates
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目次Synthesis and reactivity of dibenz[d,g]azecin-14(5H)-ones Synthesis of isoxazoline-fused chlorins by 1,3-dipolar cycloaddition reaction of porphyrins with alkyl nitrile oxides Microwave-promoted sequential three-component synthesis of tetrahydrobenzo[b]pyran in water catalyzed by heterogeneous amine grafted on silica 3-(dimethylamino)propenoate-based regioselective synthesis of 1,4-disubstituted 5-hydroxy-1H-pyrazoles Selective N-demethylation of tertiary aminofumagillols with selenium dioxide via a non-classical Polonovski type reaction A ready one-pot preparation for pteridine and isoxazolo[3,4-d]pyrimidine derivatives Synthesis of methyl 2-[(benzyloxycarbonyl)amino]-3-cyanopropenoate and its transformations into derivatives of pyrrole, 2,5-dioxoimidazolidine, 1H-pyrazole, and 4,6-diaminopyridazine Application of sulfamic acid as an eco-friendly catalyst in an expedient synthesis of benzimidazoles A concise synthesis of further thiophene analogues of kuanoniamine A Preparation of bioactive isorhapontigenin dimers through chemical transformation of bisisorhapontigenin A A convenient synthesis of papaverine analogs via photocyclization of N-acyl-α-dehydroarylalaninamide derivatives Regioselectivity in 1,3-dipolar cycloaddition of 3-(4-ethoxyphenyl)-4-cyanosydnone with propargylic esters Synthesis of 1,5-benzodiazepine derivatives catalysed by zinc chloride Asymmetric Diels-Alder reaction of 2-(p-tolylsulfinyl)-1-indolyl α,β-unsaturated enones Synthesis and structural analysis of 3,6,8,11,16-hexahydrodicyclopenta[c,h][1,6]dithiecin
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目次Synthesis and luminescent properties of bis(fluoren-9-ylidenemethyl)aromatics : green and red materials in organic electroluminescent devices The Brφnsted acid-catalyzed O-glycosidation of 1-C-alkyl-D-glucopyranose derivatives Synthesis of chiral thiazolo[3,4-a]pyrazine-5,8-diones Synthesis, structure and transformations of 2-iminoimidazolidines into novel fused heterocyclic ring systems 1,3-dibromo-5,5-dimethylhydantoin as a new imidazolidine dehydrogenating agent : synthesis of 4,5-dihydro-1H-imidazolium salts New synthesis of naratriptan Synthesis of peptidomimetic analogues of echinocandins New efficient blue-greenish electroluminescent materials of 1,3,4-oxadiazole-based pyrazole derivatives An unusual Lewis acid promoted isomerization of trans-3-halo-3-phenylthio-β-lactams Synthesis of novel symmetric cyclic indole-tetramers A total synthesis of (±)-hop ether New derivatives of 3-[(4-phenyl-5-oxo-1,2,4-triazolin-1-yl)methyl]-4-substituted 1,2,4-triazolin-5-one Synthesis of 3-cyanoflavones and their biological evaluation Synthesis of 1h-pyrazolo[4’,3’:5,6]pyrimido[2,1-a]isoindol-4(10H)-ones : derivatives of a new ring system Synthesis of some 1,3,5-triazine derivatives Organopalladium complexes 5-amino-3H-1,3,4-thiadiazoline-2-thione as metalloreceptor Unexpected reaction of 2-hydrazinoperimidine with maleic anhydride : syntheses of (8-amino-9-oxo-9,10-dihydro-8H-imidazo[1,2-a]perimidin-10-yl)acetic acid and its azomethine derivatives Crystal structure and complexation behavior of quinonediimine bearing thiadiazole unit Methylation of non-acidic alcohols of alkaloids with TMS-diazomethane : conversion of codeine to codeine-6-methyl ether
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目次Novel method for the synthesis of β-lactams by the reaction of α-bromocarboxylic acids with imines mediated by triphenylphosphine A novel and efficient Darzens reaction catalyzed by magnesium bromide Synthesis and X-ray crystal structure determinations of pyrrolidine-2,4-diones, 2-iminopyrrolidin-5-ones and 1,3-oxazine-2,4-diones derived from acetoacetanilides Copper catalyzed cyclopropanation of 1,2,3,4-tetrahydropyridin-2-ones with trimethylsilyldiazomethane : a facile and selective synthesis of 2-aza-3-oxobicyclo[4.1.0]heptanes Asymmetric synthesis of flindersiachromanone using lipase-catalyzed reaction 1-alkyl-4-(3-pyridinylamino)quinolinium-3-thiolates and their transformation into new diazaphenothiazine derivatives 1-allylation of 2-benzotelluropyrylium salts and 2-benzoselenopyrylium salts by means of allyltin reagents Synthesis of cribrostatin 6 and its related compounds Synthesis of 2’-O-methyl-5-alkynyl and alkenyl substituted uridine derivatives to screen for inhibitors of HCV 7-(imidazolidin-1-ylmethyl)quinolin-8-ol : an unexpected product from a Mannich-type reaction in basic medium Unexpected 7-methylation of oxindoles High-yielding microwave assisted synthesis of quinoline and dihydroquinoline derivatives under solvent-free conditions Pyrimidine chemistry in crop protection
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目次Synthesis of (S)-plakolide a and revision of the absolute stereochemistry of the natural (-)-plakolide A Synthesis of some benzo-14-crown-4 ethers substituted to 7,8-dihydroxy-3-phenylcoumarin derivatives Isolation, structure elucidation, and syntheses of isoneocryptotanshinone Ⅱ and tanshinlactone a from Salvia miltiorrhiza Synthesis of vinca alkaloids and related compound 103 : recognition of an unexpected reaction and its application in building the aspidospermane skeleton : simple synthesis of 15β-hydroxyvincadifformine Formal synthesis of (±)-hop ether, (±)-isoboonein and (±)-iridomyrmecin Conformations of 2,2’-bipyrrole π-systems having an electron-donating site at one terminal and electron-accepting site at the other terminal in the ground and excited states A facile synthesis of substituted 1,8-naphthyridines based on the aza-Wittig/electrocyclic ring closure strategy Designing fluorous domains : synthesis of a series of pyridinium salts bearing a perfluoroalkylated azole moiety Chemoenzymatic synthesis of naturally occurring geranyl 6-O-glycosyl-β-D-glucopyranosides A new catalytic application of a Keggin acid in the synthesis of symmetrical bis(indolyl)alkanes Two isoquinolones from the roots of Phellodendron amurense var. wilsonii Synthesis and biological evaluation of benzothiazole derivatives of pyrimidines, acrylonitriles, and coumarins A facile synthetic route to highly functionalized 2,4-pyrrolidinediones : a new base-catalyzed cyclization One-pot synthesis of 1-(2-, 3- or 4-aminophenyl)- and 1-(4-aminobenzyl)-3,4-dihydroisoqunolines Microwave-assisted gewald synthesis of 2-aminothiophenes using functional ionic liquid as soluble support Acylated cyanidin 3,7,3’-trigllucosides with p-hydroxybenzoic acid from the flowers of Dendrobium A synthesis of N-formylenamides of isoquinoline Certain cinnamonitriles react with 2-methoxyfuran to produce a new phenylcyclopane product
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目次Synthesis of octahydropyrrolo[3,2-c]pyridine derivatives by the catalytic asymmetric intramolecular cycloaddition of azomethine ylides Synthesis of chiral non racemic indolizidin-3-ones as peptidomimetic scaffold Sugar binding to an calix[4]arene-based receptor Synthetic utilization of polynitro aromatic compounds 5 : multi-centered reactivity pattern in reactions of 4,6-dinitro-1,2-benzisothiazoles and -isothiazol-3(2H)-ones with C-, N-, O-, S-, and F-nucleophiles Crystal structure of triphenyl cyamelurate (2,5,8-triphenoxy-1,3,4,6,7,9,9b-heptaazaphenalene) Total inversion of cis-C5 maxacalcitol into its trans-C5 isomer via the sulforene intermediate Recyclization of 7-fluoroalkyl-4,7-dihydroazolo[5,1-c]triazines into 5-(pyrazolinylhydrazono)azoles in the reactions with hydrazides and thiosemicarbazide Hydantoins and thiohydantoins derived from 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid Thermolysis of 5-azido-4-arylpyridazin-3(2H)-ones : an efficient and versatile synthesis of pyridazino[4,5-b]indoles Electrooxidative cyclization of hydroquinolyl alcohols Synthesis of chiral 1,2-dihydropyridines and 2,3,4-trisubstituted pyridines from α-amino acids First synthesis of trans- and cis-dendrochrysanines Total synthesis of (±)-2-epi-validamine Reduction of nitroindazoles : preparation of new amino and chloroamino derivatives Exclusive formation of α-anomers in NbCl₅-promoted ferrier rearrangement for the synthesis of 2,3-unsaturated glycosides Studies on pyrazine derivatives. ⅩⅬⅨ : synthesis and antibacterial activity of 6-methoxypyrazine-2-carboxylic acid hydrazide derivatives Synthesis of 2-amino-4,5-dihydro-1,3-selenazol-4-ones by reaction of N,N-disubstituted selenoureas with acetylenedicarboxylate Efficient new approach for the synthesis of N,N-dialkylamino-1,2,4-triazoles Synthesis of 2-amino-1,3-selenazoles by reaction of N,N-unsubstituted selenoureas with α,β-unsaturated aldehydes Synthesis and characterization of a series of alkyloxadiazolylpyridinium salts as perspective ionic liquids
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