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Table of ContentsThe syntheses of 1α-fluoro-1β-methylcarbapenem esters Formation of a dimeric complex of 14-dicyanomethylene-5,8,21,24-tetraoxa-2,11,18,27-tetrathiatricyclo[26.4.1.1¹²'¹⁷]tetratriaconta-12,15,17(34),28,30,32-hexaen-33-one with mercury(Ⅱ) chloride Simple total syntheses of marine alkaloids, batzelline C, isobatzelline C, damirone A, and makaluvamine A Total synthesis of sanjoinine-G1 Synthesis of 5-phosphonyl-2(1H)-pyridones from primary β-enaminophosphonate and acetylenic esters Inulavosin, a new thymol dimer with piscicidal activity from inula nervosa A new approach to chiral 5,5-disubstituted 2-pyrrolidinones form (S)-pyroglutamic acid Asymmetric synthesis with chiral hydrogenolysable amines : a new route to enantiopure cyclic β-amino alcohols Preparation of 2,4-dialkylidene-1,3-dithietanes from ynamines and carbon disulfide A photochemical approach to spiranic 2,3-indolines, useful intermediates in pentacyclic indole alkaloid synthesis A simple preparation of 3-carbamoylfuro[2,3-b]quinoxalin-2-ones 6-oxo-6a,12a-dehydro-α-toxicarol, a 6-oxodehydrorotenone from the roots of Derris oblonga benth A study of 2-propenethials obtained by flash vacuum pyrolysis of 2-ethenyl-1,3-dithiolane 1,1-dioxides Improved synthesis of esculetin Heck annulation on 2-position of indoles or 1H-pyrrolo[2,3-b]pyridine Synthesis of 1,3-disubstituted 1,2,4-triazolo[4,3-a]quinazolin-5-one derivatives Stereoselective synthesis of optically active diethanolamines utilizing diastereoselective reaction of 1,3-oxazolidines with grignard reagents Effective strategy for the synthesis of pyrido[1',2':1,2]imidazo[5,4-c]isoquinoline system Preparation of 15-hydroxy-Δ¹³'¹⁴-milbemycin A₄ and its transformation to 13-alkylmilbemycins Synthesis of perhydro-1,3,4-thiadiazin-5-ones and 3-arylaminothiazolidin-4-ones by the regioselective cyclocondensation of 2-sulfanylalkanoic acids or their silyl esters with methyl and aryl hydrazones A chemistry of bisbenzylisoquinoline alkaloid : isomerization of berbamine to penduline in methanol by radical reaction Two novel sarpagine-type indole alkaloids from the leaves of hunteria zeylanica in thailand Tautomerism and isomerism of heterocycles<2> Photoinduced molecular rearrangements of O-N bond-containing five-membered heterocycles. an assay for 1,2,4- and 1,2,5-oxadiazoles
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Table of ContentsAn efficient synthesis of 4-trifluoromethylated and 4-perfluoroalkylated imidazoles from mesoionic 1,3-oxazolium-5-olates Betavulgarosides I, II, III, IV, and V, hypoglycemic glucuronide saponins from the roots and leaves of beta vulgaris L. (sugar beet) Palladium-mediated formation of N-acyl-2-hydroxyindolines : a new entry into N-acylindoles 8H-anhydro-4-hydroxy-2-oxo-1,3-thiazinium hydroxides as mesoionic 1,4-dipoles Synthesis of 5-mercaptoalkylamino- and 5-anilinoalkylthiopyrazolyl-1,2,4-triazoles by ring chain transformation Photosynthesis of heteropolycyclic quinolones Synthesis of pyrazolo[3,4-b]pyrazines from 5-amino-4-nitrosopyrazoles and dimethylphenacylsulfonium bromides Formations of azazulanones and dihydroazazulanones via reactions of troponimines with heterocumulenes Synthesis of enol carbonates from a reaction of silyl enolates with 1H-imidazolylurethane Design and synthesis of sequence-specific DNA minor groove recognizing ligands of the cross-linked lexitropsin class The first formation of diazepinodiazepine and diazepinodiazocine from allenedicarboxylate and acyclic triamines and their conversion to 12- and 13-membered ring compounds Chirospecific synthesis of 2R,5S-dihydroxymethyl-3R,4R-dihydroxypyrrolidine Synthesis to 1-substituted 3,4-diarylisoquinoline derivatives Asitribin and asiminenins A and B, novel bioactive annonaceous acetogenins from the seeds of asimina triloba Goniodenin, a new bioactive annonaceous acetogenin from goniothalamus giganteus and its conversion to tri-thf acetogenins Regioselective acylation of 2,5-diamino-3-cyano-11H-pyrido[2,3-b][1,5]benzodiazepine and structural determination by X ray analysis An efficient synthesis of (S)-(-)-2,8-dimethyl-3-methylene-1-oxa-8-azaspiro[4.5]decane by cobaloxime(Ⅰ)-mediated radical cyclization Reactivity of bis(heteroaryl)methanes towards double electrophiles : synthesis of two new trinuclear [5.6.5]- and [5.5.5]-heterocyclic systems from bis(pyrazol-1-yl)methane Absolute stereochemistries of sylvaticin and 12,15-cis-sylvaticin, bioactive C-20,23-cis non-adjacent bistetrahydrofuran annonaceous acetogenins, from rollinia mucosa Asymmetric synthesis of indolizidines 167B and 223AB Tautomerism and isomerism of heterocycles<1>
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Table of ContentsDimerization of norisoacronycine A concise approach to antifertility agents : structural analogues of yuehchukene Synthesis and antibacterial activity of 1-cyclopropyl-6,8-difluoro-7-(2-substituted 4,6-dihydro-1H-pyrrolo[3,4-d]thiazol-5-yl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid Simultaneous conversion of N(1)-(2-aminoethyl)adenosine to N⁶-(2-aminoethyl)adenosine and tricyclic 1. N⁶-ethanoadenosine under mild aqueous conditions Design and synthesis of imidazolium cyclophane Alkaloids from the neutral fraction of Telitoxicum krukovii Reaction of pentafluoropyridine and α-lithiated arylacetonitriles with n-butyllithium and methyllithium in ether An efficient asymmetric aldol reaction of 4-trimethylsiloxy-6-methylene-1,3-dioxines by chiral binaphthol-titanium complex catalysis [4+2]cycloaddition reactions of 1,4-bis(trifluoromethyl)pyrido[3,4-d]pyridazine with indole-type dienophiles Pyridazines, 74 : synthesis of novel 4,5-disubstituted pyridazines by homolytic substitution and structure determination of unexpected reaction products A versatile synthesis of substituted indazoles Reactivity of N¹-acylacetamidrazones towards diethyl acetylenedicarboxylate : cyclization to ethyl pyrroleacetates and 1-acylaminopyridones Heterocyclic amidines Ⅰ : a one-step synthesis of new α-substituted imidazolylphenylacetic acids Optimization of synthesis of nitroimidazoles and nitropyrazoles based on polarographic investigations Synthesis and reactions of lithiated monocyclic azoles containing two or more hetero-atoms part Ⅵ : triazoles, tetrazoles, oxadiazoles, and thiadiazoles
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Table of ContentsA new mode for the formation of endocyclic double bond from the selenonium salt of 1,11-methanoselenomethano-5H,7H-dibenzo[b,g][1,5]diselenocin : synthesis of methanoselenomethano-bridged dibenzo[b,f]selenepin A general and efficient synthesis of optically pure S-arylmercapturates INOC reaction in gibberellin synthesis : a practical synthesis of the key intermediate for gibberellin A₁₂ Intramolecular cyclization with oxocarbenium ion : synthesis of 1-azabicyclo[3.3.1]nonene and [3.2.1]octene derivatives Diels-Alder reactions of a hydrazonocrotonate with bromonaphthoquinones Synthesis of designed functional models of bleomycin incorporating imidazole : containing lexitropsins as novel dna recognition sites Mechanism of formation of fluorescent adenosine analogues Preparation of homologous pyrazolonedicarboxylates 6-(N-imidoalkyl)aminoalkylbenzothiazolin-2-ones as ligands of the serotoninergic 5-HT1A receptors Reactions of 1,3-dithietane-2,4-diylidenebis(cyanoacetic acid alkyl esters) and 2-cyano-3,3-bis(methylsulfanyl)acrylic acid ethyl ester Acid catalyzed reactions of 2-vinylaniline derivatives with cyclic ketones of the tetralone-, chroman-4-one- and 2,3-dihydro-1H-quinolin-4-one series : new N(O)-heterocycles via 6π-electrocyclic rearrangements or [1,5] dipolar electrocyclizations part 3 Alkylation of 5-cyanoimidazole-4-carboxamide Direct introduction of acyl and ethoxycarbonyl groups into pyrimidine ring through the trimethylstannyl derivatives Synthesis of 1,2,3,4,5,6-hexahydropyrrolo[3,4-c]pyrrole dihydrobromide and 1,2,3,5-tetrahydro-2-[(4-methylphenyl)sulfonyl]pyrrolo[3,4-c]pyrrole One-pot synthesis of some fused pyran-2-ones Polycyclic N-heterocyclic compounds 46 : synthesis of thieno[2,3-h][1,6]naphthyridines from 2-(3-cyanopropylthio)pyridine-3-carbonitrile
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Table of ContentsSynthesis of a flavin receptor for regulation of ion recognition by assembling components necessary for a binding site A possible explanation for preferential stabilization of the substituent axial conformation in alkoxy- or siloxy-substituted six-membered cyclic compounds by the σ → σ* orbital overlap : remarkable effect of electron-withdrawing groups Preparation and multi-nuclear NMR study of new benzodichalcogenaphospholes Efficient synthesis and biological properties of new benzopentathiepins 1-acyl-2-alkyl-3,4-epoxy-1,2,3,4-tetrahydroquinolines : synthesis and reactions with N-nucleophiles Regioselective thermal cyclization of 3-substituted arylenaminoimine hydrochlorides, a convenient method for the synthesis of functionalized polycyclic quinoline derivatives Conversion of dihydro-1,4-oxathiin-3-carboxamide to the isomeric dihydro-1,4-oxathiin-2-carboxamide Synthesis of 17-azacholesterol Synthesis and antiviral evaluation of furopyrimidine diones cyclic and acyclic, nucleoside analogues (diethylamino)sulfur trifluoride (dast) as a useful reagent for the preparation of 2-oxazolines from 1,2-amido alcohols Studies on m-cyclophane formation from the photolysis of chloroacetamide derivatives A convenient approach to the N-substituted amino dienes, N-benzyl-5-ethenyl-3,4-dihydropyridin-2-one and N-CBZ-5-ethenyl-1,2,3,4-tetrahydropyridine Synthesis of (2R, 3R, 4R, 5R)-3,4-dihydroxy-2,5-dihydroxymethylpyrrolidine and (-)-anisomycin derivative from (S)-pyroglutamic acid derivative Preparation of 17-deoxy-E-isositsirikine cis-Nb-oxides and their use as model compounds Synthesis of substituted 1,8-naphthyridine derivatives Cyclization of 2-dicyanomethylene-1,2-dihydropyridine-3-carbonitriles with hydrogen halides : a re-examination on the regioselectivity Preparation and stereochemistry of 1,4,8,11-tetraazaperhydropyrene derivatives from N,N'-bis(3-aminopropyl)ethylenediamine Sorocenols A and B, two new isoprenylated phenols from the root bark of sorocea bonplandii baillon Synthesis of 1H-indolyl-2-benzimidazoles and 1H-indolyl-2-benzothiazoles Synthesis of fused 3a,4-dihydro-5a,H-benzofuro[3,3a-d]isoxazoles 7-hydroxyrutaecarpine from tetradium glabrifolium and tetradium ruticarpum Synthesis of egonol and (±)-machicendiol
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Table of ContentsExocyclization of novel β,β-difluoro-α-phenylvinyl sulfide with bidendate heteroatom(N,O,S) nucleophiles A convenient synthesis of benzofuran-3-acetic acids Synthesis of cribrostatins 1 and 2 Control of highly selective Ag+ transport by redox reactions between thiol and disulfide located inside a cavity of crown ether INOC reaction in alkaloid synthesis : preparation of potential intermediate for the synthesis of (-)-reserpine The reaction of quadricyclane with p-anils 3,5-dichloro-4-pyridinecarbonitrile as a key reagent in a synthesis of copper containing amine oxidase inhibitors An efficient synthesis of pyrrolo[1',2':2,3]pyridazino[6,1-a]isoindoles from 1-phthalimidopyrrole Synthesis and characterization of 6-O-α- and 6-O-β-D-glucopyranosylmorphine and 6-O-β-D-glucopyranosylcodeine Synthesis of thieno-diltiazem analogues Synthesis and reactions of dialkyl (1-R-5-amino-3-methylsulfanyl-1H-pyrazol-4-yl)phosphonates Additional bioactive triterpenoids from melia volkensii (Meliaceae) Synthesis of tetracyclic arylpyridodiazepines as potential anti HIV-1 agents 3-methyl-1-phenacylbenzotriazolium yilde : cycloadditions with acetylenic esters and aldehyde-mediated dimerization Oxidation of 1,2,3,4-tetrahydroisoquinolines to 3,4-dihydroisoquinolines with molecular oxygen catalyzed by copper(Ⅱ) chloride Pteridines, ⅭⅣ : regioselective alkoxylation of pteridines at the 6-position by N-bromo-succinimide and alcohol 6-acyllumazines from the marine polychaete, odontosyllis undecimdonta Leptocarpine, a new protopine alkaloid Total synthesis of Na,O-di-Boc-5β-cyano-Z-geissoschizine and Na-Boc-21α-cyanotetrahydroalstonine, the latter a synthetic equivalent of Na-Boc-cathenamine Carbon functionalizations on pyridine ring via trimethylstannyl derivatives : an example of fusaric acid synthesis
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Table of ContentsOn the chemistry of the 18-deoxycytochalasin H, HIV-1 protease inhibitor, L696,474 1 : degradation studies leading to the 2-isoindolone core On the chemistry of the 18-deoxycytochalasin H, HIV-1 protease inhibitor, l-696,474 2 : novel ring annulations Asymmetric synthesis of celacinnine utilizing optically active vinyl sulfoxides Conformational preference in benzyloxy- and siloxy-substituted thianes, thiane 1-oxides, and thiane 1,1-dioxides Concise enantioselective synthesis of (+)-asperlin by application of the sharpless kinetic resolution to 2-furylmethanol derivatives bearing alkenyl moiety on the side chain Reactions of 8H-furo[3,4-d]dibenz[b,f]azepine and 9H-tribenz[b,d,f,]azepine with t-butyl hypochlorite and silver trifluoroacetate : attempts to form a long-lived aromatic nitrenium ion Radical β-fragmentation of bicyclic[3.3.0]carbinolamides : synthesis of five- and eight-membered cyclic imides Synthesis of 2-substituted 1,3-benzothiazoles by aza-wittig reaction of 2-methylthio-N-triphenylphosphoranylideneaniline with acid chlorides A convenient synthesis of pyrido[3,2-b][1,4]bensothiazine derivatives via oxidative ring closure of 3-substituted 6-[N-(2-mercaptophenyl)]aminopyridines Reaction of [2.2]paracyclophane with 4-phenyl-1,2,4-triazoline-3,5-dione Synthesis of 2-(4-aryl-1E,3E-butadienyl)benzoxazoles by the horner-wadsworth-emmons reaction Synthesis of substituted pyrazolo[3,4-b]- and pyrazolo[4,3-c]phenothiazine derivatives Synthesis of 6-substituted imidazo[4,5-c]pyrazole-5-thiones C-nucleosides 24 : synthesis of pyrazolo[1,5-a]pyrimidine C-nucleoside through cyclocondensation of enaminone glycoside with aminopyrazoles Pyrrolothieno[1,4]diazepines part 1 : synthesis and study of the reaction pathway Synthesis of 3'-amino-3'-deoxyadenosine from levoglucosenone Synthesis and reactions of lithiated monocyclic azoles containing two or more hetero-atoms part Ⅴ : isothiazoles and thiazoles
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Table of ContentsCycloaddition reactions of 7-substituted acenaphtho[1,2-d]pyrazolo[1,2-a]benzotriazoles with dimethyl acetylenedicarboxylate Regiospecific synthesis of N-alkyl-4- and 5-substituted imidazoles Unexpected iodine catalyzed cyclization for synthesis of 2,2-dialkyl-2,3-dihydrobenzofurans Diene-transmissive Diels-Alder reaction of 2-vinyl-1-oxabutadiene system Isolation and structural elucidation of bioactive C-12,15-cis non-adjacent bis-THF annonaceous acetogenins Synthesis of new armed cyclopolyamines and their selective extraction properties for metal ions A synthesis of optically active platyphyllide : determination of its absolute configuration Synthesis and 1H NMR complexation study of a novel macrocyclic polyether containing 1,1'-biazulene unit A synthesis of 6-methylindole derivatives by methylthiomethylation at 6-position in indole nucleus Synthesis of 6-fluoroquinolones substituted at C-7 by 1'-demethyllincomycin and by dihydroconessimine Hypotensive constituents from the bark of holarrhena pubescens (Holarrhena antidysenterica) A synthesis of the polyhydroxylated pyrrolidines : synthesis of 1,4-dideoxy-1,4-imino-D-lyxitol and N-benzyl-4-epi-(-)-anisomycin Reaction of pentachloropyridine with α-lithiated arylacetonitriles and methyllithium in ether Synthesis and structure assignment of 1-[(2-hydroxyethoxy)methyl]- and 1-[(1,3-dihydroxy-2-propoxy)methyl]-6-azaisocytosine Synthesis of triazolidine-1,3,5,7-tetraone and pyrimidin[1,5]diazepine derivatives by carbon suboxide Regiocontrolled syntheses of benzo[b]quinolizinium and heteroisoquinolinium cations Effect of fluorine-substitution on basicity of benzo[h]quinoline, benzo[f]quinoline and quinoline An improved procedure for the preparation of aromatic heterocyclic N-oxides Thermal reaction of 1,2,4-triazolium N-allylides : formation of mesomeric betaines, 1,2,4-triazolo[4,3-a]pyridiniumides, via back-donated 1,6-cyclization Synthesis of a novel N-methoxymethylpyrrole-containing DNA minor groove binding oligopeptide related to distamycin Synthesis of 4-hydroxy-1-methylbenzimidazole and 7-hydroxy-1-methylbenzimidazole Transformation of Na-BOC-tetrahydroalstonine to Na-BOC-5β-cyanotetrahydroalstonine, Na-BOC-21α-cyanotetrahydroalstonine, and Na-BOC-3,14-didehydrotetrahydroalstonine A facile synthesis of 6-amino-1-benzyl-4-methyl- and 6-amino-1,4-dimethylhexahydro-1H-1,4-diazepines, the amine part of substituted benzamides with a potent serotonin 3 receptor antagonistic activity
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Table of ContentsSynthesis, property, and X-ray crystal structure of new dibenzophosphaselenocines 4',1'a-methanocarbocyclic adenosine analogues as potential inhibitors of S-adenosylhomocysteine hydrolase Reaction of 1-pyridiniothiobenzoylaminides with dimethyl acetylenedicarboxylate Acetylations of (±)-agelasimine-A and (±)-agelasimine-B : a racemic synthesis of purino-diterpene derived from antimicrobial metabolites of agelas mauritiana Efficient and regioselective photocyclization reactions of N-[(ω-trimethylsilylmethoxy)polyoxalkyl]phthalimides to azacrown ethers Substrate specificity of vinorine hydroxylase, a novel membrane-bound key enzyme of Rauwolfia indole alkaloid biosynthesis Photosynthesis of heteropolycyclic diquinolones twofold photodehydrohalogenation reaction of benzo[1,2-b:4,5-b']dithiophene- and dithieno[3,2-b:2',3'-d]thiophenedicarboxanilides A controlled stepwise oxidation of ethyl 2-oxothiazolidine-4-carboxylate to the corresponding 2-hydroxythiazole Substituted benzimidazoles part Ⅰ : synthesis and properties of some 2-aryl-5-fluoro-6-(4-methyl-1-piperazinyl)-1H-benzimidazoles Stereoselective reduction of the double bond in Δ⁵-3-oxo-4-azasteroids Synthesis of 2-substituted isothiazolo[5,4-b]pyridin-3(2H)-one 1,1-dioxides Synthesis of 17- and 21-membered macrocycles incorporating the chiral 1,1'-binaphthyl backbone and nitrogen, oxygen, and phosphorus donor atoms Ficusins A and B, two new cyclic-monoterpene-substituted isoflavones from Ficus septica Barm. F. Synthesis of N-substituted 3-aminomethyl-2,3-dihydrofuro[2,3-c]pyridines, potent serotoninergic ligands Reaction of 4-amino-1,2,4-triazolium salts with polarized olefins New diels-alder reactions of oxy-functionalized 3-vinylindoles with carbodienophiles Trichilinins B and C, two new limonoids from Melia toosendan Synthesis of 6-substituted 2-phenyloxazolo[4,5-b]pyridines Sorocenols C-F, four new isoprenylated phenols from the root bark of Sorocea bonplandii baillon Facile preparation of (3S)-1,3-dimethyl-3-cyanomethyl-5-ethoxyoxindole from Julian's nitrile enriched in the (3S)-enantiomer Chemistry of persistent free bi- and polyradicals
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Table of ContentsSynthesis of 2-(benzopyran-4-yl)pyridine N-oxide K⁺ channnel opener via palladium-catalyzed cross-coupling reaction A synthetic entry to 1- and 2-aminopyrazolo[3,4-d]-1,2,3-triazoles Isolation of Δ³-1,2,3-thiadiazolin-1-ones, a key intermediate of the Hurd-Mori reaction Synthesis and chemiluminescence of 3-biphenylyl-4,4-diisopropyl-3-methoxy-1,2-dioxetanes A short synthetic approach to enantiomerically pure (-)-anisomycin A simple and efficient one pot synthesis of 4-oxo-spiro[thiazolidine-2,2'(1'H)quinolines] and their reactions with DDQ A novel aspect on the 1,2-alkyl migration reaction with trialkyl 1-substituted indol-2-ylborates Synthesis of tricyclic benzazepines and their dopamine D₁- and D₂-affinity Reaction of 5-aminobenzotriazoles with methyl propiolate : formation of triazolo[4,5-f]quinolines and related compounds : unusual products in the michael addition reaction of 2-methyl-2H-5-aminobenzotriazole A facile route for the synthesis of some new spiro[indoline-3,3'-indan]-2,1'-dione derivatives Synthesis of A 1,2-dithiin mediated by electrophilic reagents Synthesis of a novel 6,5-bicyclic hexahydropyridazine derivative Enantiospecific synthesis of 2,3,5-substituted piperidines as analogues of nojirimycin Synthesis of 2-alkylthio analogues of AZT and their activity against HIV-1 Convenient synthesis of cycloalkene-fused phthalazinones Reaction products of 1,3-indandione with heteroaromatic carbaldehydes : synthesis, structure and NMR-investigations Characterization of decamethyl and ethoxycarbonyl pentaphyrins Polycyclic N-heterocyclic compounds 49 : new synthetic method of furo[3,2-f][1,7]naphthyridine skeleton Structural and conformational analysis of naturally occurring cularine N-oxide alkaloids Silver catalyzed cyclization of alkynoic acids : efficient synthesis of 3-alkylidenephthalides, γ -alkylidenebutenolides, and γ-alkylidenebutyrolactones
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