Short and Long-term effects of pharyngeal electrical stimulation on swallowing performance in healthy humans

• 資料種別: 博士論文
• タイトル: Short and Long-term effects of pharyngeal electrical stimulation on swallowing performance in healthy humans
• 著者・編者: Takeishi, Ryosuke
• 出版事項: 新潟大学
• 出版年月日等: 2015-03-23
• 出版年（W3CDTF）: 2015-03-23
• 並列タイトル等: Short and Long-term effects of pharyngeal electrical stimulation on swallowing performance in healthy humans; 咽頭電気刺激がもたらす嚥下機能への短期および長期効果
• 授与機関名: 新潟大学
• 授与年月日: 2015-03-23
• 授与年月日（W3CDTF）: 2015-03-23
• 報告番号: 甲第4016号
• 学位: 博士（歯学）
• 博論授与番号: 甲第4016号
• 本文の言語コード: eng
• 件名標目: pharyngeal electrical stimulation; voluntary swallow; involuntary swallow; dysphagia
• 一般注記: Pharyngeal electrical stimulation (PES) has been found to facilitate voluntary swallowing, This study investigated how PES contributes to modulation of swallowing function in 12 healthy humans. In the the involuntary swallowing test, distilled water was injected onto the pharynx at 0.1 mL/s and the onset latency of the first swallow was measured. In the the voluntary swallowing test, subjects swallowed their own saliva as quickly as possible for 30 s and the number of swallows was counted. Voluntary and involuntary swallowing was evaluated before (control), immediately after and every 10 min after 10-min PES (75% of tolerated sensation, 5 Hz and 1 ms pulse) for 60 minutes. Voluntary swallowing test during PES was also conducted before (control) and 60 min after 10-min PES. The onset latency in the involuntary swallowing test tended to decrease and the number of voluntary swallows tended to decrease immediately after 10-min PES. There was a negative correlation between the changes. The number of voluntary swallows with PES significantly increased 60 min after 10-min PES as compared with baseline. Repeat 10-min PES over 5 days significantly facilitated voluntary swallowing, with significant increases in the number of voluntary swallows. Involuntary swallowing function was not affected by PES. The results suggest that PES may have a long-term facilitatory effect on initiation of voluntary swallowing even in healthy humans but not on peripherally evoked swallowing. Daily repeat application of PES may also be useful in increasing the number of voluntary swallows. Physiological implications for the modulation and possibility of using the methods in dysphagic patients are discussed.; 学位の種類: 博士（歯学）. 報告番号: 甲第4016号. 学位記番号: 新大院博（歯）甲第329号. 学位授与年月日: 平成27年3月23日; 新大院博（歯）甲第329号; 開始ページ : 1; 終了ページ : 26
• 国立国会図書館永続的識別子: info:ndljp/pid/9424957; https://dl.ndl.go.jp/pid/9424957
• コレクション（共通）: 障害者向け資料
• コレクション（障害者向け資料：レベル1）: テキストデータ
• コレクション（個別）: 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• 収集根拠: 博士論文（自動収集）
• 受理日（W3CDTF）: 2015-07-01T13:17:09+09:00
• 作成日（W3CDTF）: 2019-08-05
• 記録形式（IMT）: application/pdf
• オンライン閲覧公開範囲: 国立国会図書館内限定公開
• デジタル化資料送信: 図書館・個人送信対象外
• 遠隔複写可否（NDL）: 可
• 掲載誌（URI）: http://hdl.handle.net/10191/32185
• 連携機関・データベース: 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp