Short and Long-term effects of pharyngeal electrical stimulation on swallowing performance in healthy humans

• Material Type: 博士論文
• Title: Short and Long-term effects of pharyngeal electrical stimulation on swallowing performance in healthy humans
• Author/Editor: Takeishi, Ryosuke
• Publication, Distribution, etc.: 新潟大学
• Publication Date: 2015-03-23
• Publication Date (W3CDTF): 2015-03-23
• Alternative Title: Short and Long-term effects of pharyngeal electrical stimulation on swallowing performance in healthy humans; 咽頭電気刺激がもたらす嚥下機能への短期および長期効果
• Degree grantor/type: 新潟大学
• Date Granted: 2015-03-23
• Date Granted (W3CDTF): 2015-03-23
• Dissertation Number: 甲第4016号
• Degree Type: 博士（歯学）
• Conferring No. (Dissertation): 甲第4016号
• Text Language Code: eng
• Subject Heading: pharyngeal electrical stimulation; voluntary swallow; involuntary swallow; dysphagia
• Note (General): Pharyngeal electrical stimulation (PES) has been found to facilitate voluntary swallowing, This study investigated how PES contributes to modulation of swallowing function in 12 healthy humans. In the the involuntary swallowing test, distilled water was injected onto the pharynx at 0.1 mL/s and the onset latency of the first swallow was measured. In the the voluntary swallowing test, subjects swallowed their own saliva as quickly as possible for 30 s and the number of swallows was counted. Voluntary and involuntary swallowing was evaluated before (control), immediately after and every 10 min after 10-min PES (75% of tolerated sensation, 5 Hz and 1 ms pulse) for 60 minutes. Voluntary swallowing test during PES was also conducted before (control) and 60 min after 10-min PES. The onset latency in the involuntary swallowing test tended to decrease and the number of voluntary swallows tended to decrease immediately after 10-min PES. There was a negative correlation between the changes. The number of voluntary swallows with PES significantly increased 60 min after 10-min PES as compared with baseline. Repeat 10-min PES over 5 days significantly facilitated voluntary swallowing, with significant increases in the number of voluntary swallows. Involuntary swallowing function was not affected by PES. The results suggest that PES may have a long-term facilitatory effect on initiation of voluntary swallowing even in healthy humans but not on peripherally evoked swallowing. Daily repeat application of PES may also be useful in increasing the number of voluntary swallows. Physiological implications for the modulation and possibility of using the methods in dysphagic patients are discussed.; 学位の種類: 博士（歯学）. 報告番号: 甲第4016号. 学位記番号: 新大院博（歯）甲第329号. 学位授与年月日: 平成27年3月23日; 新大院博（歯）甲第329号; 開始ページ : 1; 終了ページ : 26
• Persistent ID (NDL): info:ndljp/pid/9424957; https://dl.ndl.go.jp/pid/9424957
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2015-07-01T13:17:09+09:00
• Date Created (W3CDTF): 2019-08-05
• Format (IMT): application/pdf
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Periodical Title (URI): http://hdl.handle.net/10191/32185
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp