A Zinc Chelator TPEN Attenuates Airway Hyperresponsiveness Airway Inflammation in Mice In Vivo

• 資料種別: 記事
• タイトル: A Zinc Chelator TPEN Attenuates Airway Hyperresponsiveness Airway Inflammation in Mice In Vivo
• 著者標目: Fukuyama Satoru; Matsunaga Yuko; Zhanghui Wang; Noda Naotaka; Asai Yukari; Moriwaki Atsushi; Matsumoto Takafumi; Nakano Takako; Matsumoto Koichiro; Nakanishi Yoichi; Inoue Hiromasa
• 出版年月日等: 2011
• 出版年（W3CDTF）: 2011
• タイトル（掲載誌）: Allergology International
• 巻号年月日等（掲載誌）: 60 3
• 掲載巻: 60
• 掲載号: 3
• 掲載ページ: 259-266
• 掲載年月日（W3CDTF）: 2011
• ISSN（掲載誌）: 13238930
• ISSN-L（掲載誌）: 13238930
• 出版事項（掲載誌）: Japanese Society of Allergology
• 本文の言語コード: en
• 件名標目: airway hyperresponsiveness; asthma; zinc chelator TPEN
• 対象利用者: 一般
• 標準番号（その他）: PMID : 21364313
• DOI: 10.2332/allergolint.09-oa-0167
• オンライン閲覧公開範囲: インターネット公開
• 関連情報（URI）: http://api.elsevier.com/content/article/PII:S1323893015305268?httpAccept=text/xml; http://api.elsevier.com/content/article/PII:S1323893015305268?httpAccept=text/plain; https://search.jamas.or.jp/link/ui/2012169519
• 参照: Role of Zinc Signaling in the Regulation of Mast Cell-, Basophil-, and T Cell-Mediated Allergic Responses; https://cir.nii.ac.jp/crid/1360285711334389632; Frequency-dependent airway hyperresponsiveness in a mouse model of emphysema and allergic inflammation; https://cir.nii.ac.jp/crid/1360285712710169216; Inhibition of PI3Kδ Enhances Poly I:C-Induced Antiviral Responses and Inhibits Replication of Human Metapneumovirus in Murine Lungs and Human Bronchial Epithelial Cells; https://cir.nii.ac.jp/crid/1360568694205160832; Group <scp>III</scp> secreted phospholipase <scp>A₂</scp>‐driven lysophospholipid pathway protects against allergic asthma; https://cir.nii.ac.jp/crid/1360865816802512128; A new zinc chelator, IPZ-010 ameliorates postoperative ileus; https://cir.nii.ac.jp/crid/1361412891563342976
• 参照: Mast Cells Can Amplify Airway Reactivity and Features of Chronic Inflammation in an Asthma Model in Mice; https://cir.nii.ac.jp/crid/1360292619014954624; Mast cell–derived TNF contributes to airway hyperreactivity, inflammation, and TH2 cytokine production in an asthma model in mice; https://cir.nii.ac.jp/crid/1360292619757476096; Zinc Signals Are Essential for Lipopolysaccharide-Induced Signal Transduction in Monocytes; https://cir.nii.ac.jp/crid/1360292619773489152; TNF can contribute to multiple features of ovalbumin-induced allergic inflammation of the airways in mice; https://cir.nii.ac.jp/crid/1360574096085234944; Aluminium Hydroxide Adjuvant Initiates Strong Antigen-Specific Th2 Responses in the Absence of IL-4- or IL-13-Mediated Signaling; https://cir.nii.ac.jp/crid/1360576197922374528; Eosinophilic Inflammation in Asthma; https://cir.nii.ac.jp/crid/1360855568806355840; Visualization of labile zinc and its role in apoptosis of primary airway epithelial cells and cell lines; https://cir.nii.ac.jp/crid/1360855569544859776; The role of allergy in the development of asthma; https://cir.nii.ac.jp/crid/1361137044710892800; SUBEPITHELIAL FIBROSIS IN THE BRONCHI OF ASTHMATICS; https://cir.nii.ac.jp/crid/1361137045426362496; Complexity and Redundancy in the Pathogenesis of Asthma: Reassessing the Roles of Mast Cells and T Cells; https://cir.nii.ac.jp/crid/1361418519548048128; Zinc: Mechanisms of Host Defense1,; https://cir.nii.ac.jp/crid/1361699993809282560; Protection by the heavy metal chelator N,N,N′,N′-tetrakis (2-Pyridylmethyl)ethylenediamine (TPEN) against the lethal action of botulinum neurotoxin A and B; https://cir.nii.ac.jp/crid/1361981469516701056; Modulating the immune response by oral zinc supplementation: a single approach for multiple diseases; https://cir.nii.ac.jp/crid/1361981469551130496; Chronic exposure to TNF-α increases airway mucus gene expression; https://cir.nii.ac.jp/crid/1361981470975788928; IgE-Dependent Mast Cell Activation Potentiates Airway Responses in Murine Asthma Models; https://cir.nii.ac.jp/crid/1362262945619154688; Zinc signals promote IL‐2‐dependent proliferation of T cells; https://cir.nii.ac.jp/crid/1362262946274558848; Airway mucus hypersecretion in asthma: an undervalued pathology?; https://cir.nii.ac.jp/crid/1362544418843474944; Signalling through the high-affinity IgE receptor FcεRI; https://cir.nii.ac.jp/crid/1362544419517152640; Effect of metal chelating agents on the direct and seizure-related neuronal death induced by zinc and kainic acid; https://cir.nii.ac.jp/crid/1362544420257220480; The development of allergic inflammation; https://cir.nii.ac.jp/crid/1362544420511376896; Zinc metabolism in airway epithelium and airway inflammation: basic mechanisms and clinical targets. A review; https://cir.nii.ac.jp/crid/1362825894446463872; Diverse effects of metal chelating agents on the neuronal cytotoxicity of zinc in the hippocampus; https://cir.nii.ac.jp/crid/1362825895924473216; Differential Regulation by Glucocorticoid of Interleukin-13–induced Eosinophilia, Hyperresponsiveness, and Goblet Cell Hyperplasia in Mouse Airways; https://cir.nii.ac.jp/crid/1363107368334692992; IMMUNOLOGIC BASIS OF ANTIGEN-INDUCED AIRWAY HYPERRESPONSIVENESS; https://cir.nii.ac.jp/crid/1363107371065053056; Zinc chelators inhibit eotaxin, RANTES, and MCP-1 production in stimulated human airway epithelium and fibroblasts; https://cir.nii.ac.jp/crid/1363388843514684160; A<scp>sthma</scp>: Mechanisms of Disease Persistence and Progression; https://cir.nii.ac.jp/crid/1363388844954691072; Functional Significance of Zinc-Related Signaling Pathways in Immune Cells; https://cir.nii.ac.jp/crid/1363670320526511360; Zinc Is Required for FcεRI-Mediated Mast Cell Activation; https://cir.nii.ac.jp/crid/1364233268689361920; TNF-α induces the late-phase airway hyperresponsiveness and airway inflammation through cytosolic phospholipase A2 activation; https://cir.nii.ac.jp/crid/1364233270557905920
• 連携機関・データベース: 国立情報学研究所 : CiNii Research; https://cir.nii.ac.jp/
• 提供元機関・データベース: Japan Link Center; https://japanlinkcenter.org/top; Crossref; https://www.crossref.org; PubMed; https://pubmed.ncbi.nlm.nih.gov; CiNii Articles; 科学研究費助成事業データベース; https://kaken.nii.ac.jp/ja
• NII論文ID: 130004723036

• 要約等: <b>Background:</b> Zinc is an essential element required for the cell metabolism, including gene transcription, signal transduction, immunity, and apo...