The Effect of Different Surgical Instruments for Bone Regeneration under the Surgery of Bone Defect on Rat Calvaria

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The Effect of Different Surgical Instruments for Bone Regeneration under the Surgery of Bone Defect on Rat Calvaria

Material type: 博士論文

Author: 古森, 喬

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Material Format: Digital

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Name of awarding university/degree: 大阪歯科大学,博士（歯学）

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Note (General)：: In this study, we compared the healing process of bone defects treated with a trephine bur with those treated with an ultrasonic knife using a critica...

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Material Type: 博士論文
Title: The Effect of Different Surgical Instruments for Bone Regeneration under the Surgery of Bone Defect on Rat Calvaria
Author/Editor: 古森, 喬
Author Heading: 古森, 喬
Alternative Title: ラットの頭蓋骨手術に用いる器具の違いが骨再生に及ぼす影響
Degree grantor/type: 大阪歯科大学
Date Granted: 2022-06-22
Dissertation Number: 乙第1641号
Degree Type: 博士（歯学）
Text Language Code: eng
Subject Heading: Bone regeneration
Surgical instruments
Calvaria
Ultrasonic knife
Trephine bur
Target Audience: 一般
Note (General): In this study, we compared the healing process of bone defects treated with a trephine bur with those treated with an ultrasonic knife using a critical-sized bone defect model on rat calvaria. Nine-millimeter critical-size bone defects were prepared using both instruments in the calvaria of adult Sprague-Dawley rats. One and four weeks after the osteotomy, weperformed a histomorphometric analysis to evaluate bone regeneration around the cutting surface. Quantitative micro-computed tomography analyses of the bone volume in both groups suggested that ultrasonic knife surgery resulted in superior bone formation compared to that in trephine bur surgery. Furthermore, at the cutting surface, the ultrasonic knife treatment retained the alkaline phosphatase activity and new bone formation, which was identified using calcein staining, even one week after surgery. Considering the speed and volume of bone regeneration, the ultrasonic knife is likely to be the preferred over the trephine bur to perform osteotomies in implant surgery.
2022年度
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https://osaka-dent.repo.nii.ac.jp/?action=repository_action_common_download&item_id=338&item_no=1&attribute_id=20&file_no=1
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Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）
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Original Data Provider (Database): 大阪歯科大学 : 大阪歯科大学学術リポジトリ