Functionally validated SCN5A variants allow interpretation of pathogenicity and prediction of lethal events in Brugada syndrome

• Material Type: 博士論文
• Title: Functionally validated SCN5A variants allow interpretation of pathogenicity and prediction of lethal events in Brugada syndrome
• Author/Editor: 木本, 浩貴
• Author Heading: 木本, 浩貴
• Publication, Distribution, etc.: Oxford University Press
• Publication Date: 2021-12-01
• Publication Date (W3CDTF): 2021-12-01
• Alternative Title: 機能的に検証されたSCN5A変異は，ブルガダ症候群の病原性の解釈と致死性イベントの予測を可能にする
• Periodical title: European Heart Journal
• No. or year of volume/issue: 42 29
• Volume: 42
• Issue: 29
• Pages: 2854-2863
• ISSN (Periodical Title): ISSN : 0195-668X; ISSN : 1522-9645
• Degree grantor/type: Nagasaki University (長崎大学)
• Date Granted: 2021-12-01
• Dissertation Number: 甲医歯薬第1378号
• Degree Type: 博士(医学)
• Text Language Code: eng
• Subject Heading: Brugada syndrome; SCN5A mutations; Lethal arrhythmia; Variants of unknown significance; Whole-exome sequencing; Patch-clamp
• Target Audience: 一般
• Note (General): 長崎大学学位論文 学位記番号:博(医歯薬)甲第1378号 学位授与年月日:令和3年12月1日; Author: Taisuke Ishikawa, Hiroki Kimoto, Hiroyuki Mishima, Kenichiro Yamagata, Soshiro Ogata, Yoshiyasu Aizawa, Kenshi Hayashi, Hiroshi Morita, Tadashi Nakajima, Yukiko Nakano, Satoshi Nagase, Nobuyuki Murakoshi, Shinya Kowase, Kimie Ohkubo, Takeshi Aiba, Shimpei Morimoto, Seiko Ohno, Shiro Kamakura, Akihiko Nogami, Masahiko Takagi, Matilde Karakachoff, Christian Dina, Jean-Jacques Schott, Koh-Ichiro Yoshiura, Minoru Horie, Wataru Shimizu, Kunihiro Nishimura, Kengo Kusano, Naomasa Makita; Citation: European Heart Journal, 42(29), pp. 2854–2863; 2021; Nagasaki University (長崎大学), 博士(医学) (2021-12-01)
• Format (IMT): application/pdf
• Access Restrictions: インターネット公開
• Rights (production): © 2021 The Author(s) 2021. Published by Oxford University Press on behalf of European Society of Cardiology. This is a pre-copy-editing, author-produced PDF of an article accepted for publication in European journal of cardio-thoracic surgery following peer review. The definitive publisher-authenticated version European Heart Journal, 42(29), pp. 2854–2863; 2021 is available online at:https://doi.org/10.1093/eurheartj/ehab254.
• Related Material (URI): HDL; http://hdl.handle.net/10069/00041139
• Related Material (DOI): 10.1093/eurheartj/ehab254
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 長崎大学 : 長崎大学学術研究成果リポジトリ

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