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Bibliographic Record
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- Material Type
- 図書
- Author/Editor
- 友田, 明美Tomoda, Akemi
- Author Heading
- Publication, Distribution, etc.
- Publication Date
- 2010-05-31
- Publication Date (W3CDTF)
- 2010-05-31
- Alternative Title
- Neurobiological and behavioral consequences of exposure to childhood traumatic stress and preliminary evidence for sensitive periods in the effect of childhood abuse on regional brain development.ショウニ ギャクタイ ノ ノウ ハッタツ ニ オヨボス エイキョウ ト ビンカンキ ニ カンスル ケンキュウ
- Text Language Code
- jpn
- Target Audience
- 一般
- Note (General)
- 出版タイプ： VoRtype:研究報告書小児期の被虐待による脳発達に及ぼす影響として、被性的虐待の視覚野への影響、被暴言虐待の聴覚野への影響、被厳格体罰の前頭前野への影響、両親間のDV 目撃による視覚野への影響が高解像度MRI 解析で明らかになった。さらに年齢によって虐待ストレスの局所脳へ及ぼす影響が異なり、しかも様々な領域で時期が異なる感受性（臨界）期の存在を示唆する所見が得られた。小児期の虐待ストレスが、感覚系が活動的に働く領域に影響を及ぼしており、脳構成細胞である軸索・デンドライト・グリアを含めたネットワーク形成不全が起こっている可能性が示唆された。Brain development is largely guided by genetic factors, but thefinal form is sculpted by environmental factors and early experience. Exposure to traumaticevents such as childhood abuse and neglect, have been associated with alterations in thesize or functional activity of a variety of brain regions. We have conducted a voxel-basedmorphometry (VBM) study in young adults with histories of exposure to repeated episodesof childhood sexual abuse and found that the most significant differences were bilateralreductions in gray matter volume (GMV) in the visual cortex (BA 17, 18). Similarly, weconducted a VBM analysis in young adults exposed to parental verbal aggression, andobserved an increase in the left superior temporal gyrus (BA 22). These findings fit withan emerging hypothesis that exposure to early adversity may be associated with alterationsin sensory systems that process and convey the adverse sensory experience. Severe abuseduring childhood can cause abnormal brain development and have a negative impact laterin life.
- Data Provider (Database)
- 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）
- Original Data Provider (Database)
- 熊本大学 : 熊本大学学術リポジトリ