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肺気腫の新規発症機序 : 接着分子CADM1の細胞内断片による肺胞上皮アポトーシス

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肺気腫の新規発症機序 : 接着分子CADM1の細胞内断片による肺胞上皮アポトーシス

Material type
文書・図像類
Author
萩山, 満
Publisher
近畿大学
Publication date
2014-01-01
Material Format
Digital
Capacity, size, etc.
-
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Note (General):

研究種目:若手研究(B); 研究期間:2013~2014; 課題番号:25860302; 研究分野:実験病理; 科研費の分科・細目:Research Paperapplication/pdf

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https://kaken.nii.ac.jp/d/r/60632718.ja.html

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Summary, etc.:

研究成果の概要(和文): 肺気腫の原因である蛋白分解酵素活性上昇と肺胞上皮アポトーシスを結び付ける分子機序は不明であった. 肺胞上皮の接着分子CADM1の機能的制御に細胞外切断(shedding)がある. ウエスタン法にて肺気腫ではsheddinが亢進し, TUNEL法にて肺胞上皮アポトーシスの上昇...

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Digital

Material Type
文書・図像類
Author/Editor
萩山, 満
Author Heading
Publication, Distribution, etc.
Publication Date
2014-01-01
Publication Date (W3CDTF)
2014-01-01
Alternative Title
Increased ectodomain shedding of lung-epithelial cell adhesion molecule 1 as a cause of increased alveolar cell apoptosis in emphysema
Periodical title
科学研究費助成事業研究成果報告書 (2014. )
Pages
1-5