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脳腫瘍幹細胞に対するDEPDC1を標的とした新規治療法の開発

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脳腫瘍幹細胞に対するDEPDC1を標的とした新規治療法の開発

Material type
文書・図像類
Author
菊地, 亮吾
Publisher
-
Publication date
2018
Material Format
Digital
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-
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-
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Notes on use

Note (General)：

type:text脳腫瘍幹細胞を用いたモデルマウスにおいて、DEPDC1を抑制させると、腫瘍内でのアポトーシス/ネクローシス細胞の増加が認められ、著明な生存期間の延長を認めた。CD4, CD8陽性のリンパ球が腫瘍周囲に増殖しており、DEPDC1の抑制が腫瘍の免疫寛容を阻害する可能性を示した。GL26...

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科研費研究者番号 : 10594723

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Digital

Material Type
文書・図像類
Title
脳腫瘍幹細胞に対するDEPDC1を標的とした新規治療法の開発
Author/Editor
菊地, 亮吾
Author Heading
菊地, 亮吾
Publication Date
2018
Publication Date (W3CDTF)
2018
Alternative Title
ノウシュヨウ カンサイボウ ニ タイスル DEPDC1 オ ヒョウテキ ト シタ シンキ チリョウホウ ノ カイハツ
Nōshuyō kansaibō ni taisuru DEPDC1 o hyōteki to shita shinki chiryōhō no kaihatsu
Development of new treatment for brain tumor stem cells
Periodical title
科学研究費補助金研究成果報告書
Text Language Code
jpn
eng
Subject Heading
脳腫瘍幹細胞,ペプチドワクチン,DEPDC1,PD-1抗体