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炎症状態におけるIgAの腸管分泌制御に果たすMZB1の役割の解明

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炎症状態におけるIgAの腸管分泌制御に果たすMZB1の役割の解明

Material type
文書・図像類
Author
王, 継揚
Publisher
-
Publication date
2022
Material Format
Digital
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Note (General)：

type:text本研究では、炎症状態におけるIgA分泌制御機構並びにIgAが炎症性腸炎による大腸がんの抑制に果たす役割について解析を行い、以下の成果が得られた。１）分子シャペロンMZB1は、形質細胞内のIgAの分解を抑制し、腸管へのIgA分泌を促進する。２）単細胞RNAシーケンスの結果、通常状態に...

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Material Type
文書・図像類
Title
炎症状態におけるIgAの腸管分泌制御に果たすMZB1の役割の解明
Author/Editor
王, 継揚
Author Heading
王, 継揚
Publication Date
2022
Publication Date (W3CDTF)
2022
Alternative Title
エンショウ ジョウタイ ニ オケル IgA ノ チョウカン ブンピツ セイギョ ニ ハタス MZB1 ノ ヤクワリ ノ カイメイ
Enshō jōtai ni okeru IgA no chōkan bunpitsu seigyo ni hatasu MZB1 no yakuwari no kaimei
Role of MZB1 in the regulation of gut IgA secretion during inflammatory conditions
Periodical title
科学研究費補助金研究成果報告書
Text Language Code
jpn
eng
Subject Heading
IgA,MZB1,Mucosal inflammation,Colitis,Colorectal cancer