文書・図像類

肝線維化を伴う肝発がん・再発の新規治療標的因子の機能解析

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肝線維化を伴う肝発がん・再発の新規治療標的因子の機能解析

Material type
文書・図像類
Author
岡田, 光ほか
Publisher
-
Publication date
2021-05-25
Material Format
Digital
Capacity, size, etc.
-
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Note (General):

金沢大学医薬保健学総合研究科申請者は、ヒト臨床検体及びこれまでのモデルマウスから肝線維化病態進行及び肝細胞癌の悪性度の進行に伴いPKMのバリアントであるPKM1とPKM2共に発現が増加することを発現解析から確認した。PKM1は、肝星細胞を活性化させ筋線維芽細胞に形質転換することで肝線維化病態を亢進さ...

Related materials as well as pre- and post-revision versions

https://kaken.nii.ac.jp/search/?qm=50788916

https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19K17485/

https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-19K17485/19K17485seika/

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Digital

Material Type
文書・図像類
Author/Editor
岡田, 光
Okada, Hikari
Publication Date
2021-05-25
Publication Date (W3CDTF)
2021-05-25
Alternative Title
Functional analysis of new therapeutic target factors for tumorigenesis and recurrence with liver fibrosis
Periodical title
令和2(2020)年度 科学研究費補助金 若手研究 研究成果報告書 = 2020 Fiscal Year Final Research Report
No. or year of volume/issue
2019-04-01 - 2021-03-31
Volume
2019-04-01 - 2021-03-31