Search by Bookstore
Holdings of Libraries in Japan
This page shows libraries in Japan other than the National Diet Library that hold the material.
Please contact your local library for information on how to use materials or whether it is possible to request materials from the holding libraries.
other
Search by Bookstore
Bibliographic Record
You can check the details of this material, its authority (keywords that refer to materials on the same subject, author's name, etc.), etc.
- Material Type
- 文書・図像類
- Author/Editor
- 白藤, 梨可
- Author Heading
- 白藤, 梨可 シラフジ, リカ
- Publication, Distribution, etc.
- Alternative Title
- Study on the molecular mechanism of autophagy at nonfeeding periods in the hard tick Haemaphysalis longicornis
- Text Language Code
- jpn
- Subject Heading
- Target Audience
- 一般
- Note (General)
- 2009-2010年度科学研究費補助金(研究活動スタート支援)研究成果報告書 課題番号：21880038 研究代表者：白藤梨可 (鹿児島大学農学部プロジェクト研究員)獣医・医学上重要な吸血性節足動物マダニについて、数年に及ぶ生活史の大半を未吸血・飢餓状態で過ごすという性質に着目し、マダニの飢餓耐性を担う分子基盤の解明を実施した。未吸血マダニにおけるオートファジー関連遺伝子群の発現抑制ならびにオートファジー阻害剤処理により、実験群のマダニにおいて寿命が短縮した。このことから、宿主探索時のマダニはオートファジーを活用して栄養分を補い、飢餓に耐えていることが示唆された。Ticks are hematophagous arthropods and they can survive without food during the host-seeking period for several months to years. This study focused on autophagy which is induced during starvation in eukaryotes. Knockdown of autophagy-related genes and treatment with autophagy inhibitor led to a shortened life span in adult ticks. Tick autophagy might help compensate for the loss of nutrients derived from host blood components during the non-feeding period.