Correlation of 3D Arterial Spin Labeling and Multi-Parametric Dynamic Susceptibility Contrast Perfusion MRI in Brain Tumors

• Material Type: 博士論文
• ISSN: 1349-6867
• Title: Correlation of 3D Arterial Spin Labeling and Multi-Parametric Dynamic Susceptibility Contrast Perfusion MRI in Brain Tumors
• Volume: 63 3-4
• Author/Editor: Khashbat, Delgerdalai; Abe, Takashi; Ganbold, Mungunbagana; Iwamoto, Seiji; Uyama, Naoto; Irahara, Saho; Otomi, Youichi; Harada, Masafumi; Kageji, Teruyoshi; Nagahiro, Shinji
• Author Heading: Khashbat, Delgerdalai; Abe, Takashi; Ganbold, Mungunbagana; Iwamoto, Seiji; Uyama, Naoto; Irahara, Saho; Otomi, Youichi; Harada, Masafumi; Kageji, Teruyoshi; Nagahiro, Shinji
• Publication, Distribution, etc.: Faculty of Medicine Tokushima University
• Publication Date: 2016-08
• Publication Date (W3CDTF): 2016-08
• Alternative Title: 脳腫瘍における動脈スピンラベリング法及び多変量ダイナミック磁化率コントラスト灌流MRI法の比較; ASL and DSC MRI of brain tumors
• Periodical title: The Journal of Medical Investigation
• Degree grantor/type: 徳島大学
• Date Granted: 2016-03-23
• Date Granted (W3CDTF): 2016-03-23
• Dissertation Number: 甲第2956号
• Degree Type: 博士（医学）
• Conferring No. (Dissertation): 甲第2956号
• Text Language Code: eng
• Subject Heading: magnetic resonance imaging; arterial spin labeling; dynamic susceptibility contrast perfusion; time to maximum; brain tumor
• Target Audience: 一般
• Note (General): Purpose : Arterial spin labeling (ASL) is an alternative method to Dynamic susceptibility contrast (DSC) perfusion MRI for brain tumors. However, ASL cerebral blood flow (CBF) can be easily affected by transit time. DSC MRI derived time to maximum of the residue function (Tmax) is possible to assess the transit time on ASL. Methods : Thirty patients with brain tumors were studied using ASL and DSC MRI. The relative cerebral blood flow (rCBF), relative cerebral blood volume (rCBV), Tmax, and mean transit time (MTT) were obtained from DSC MRI. The ratios of the parameters were analyzed. Results : ASL CBF ratio correlated with the DSC rCBF ratio (r=0.78, p<0.001) and rCBV ratio (r=0.74, p<0.001). There was a moderate correlation between ASL CBF ratio and Tmax ratio (r=-0.43, p<0.05) in brain tumors. Conclusions : ASL CBF strongly correlated with DSC rCBF and rCBV. In addition, a negative correlation was found between ASL CBF and Tmax in brain tumors, indicating that these parameters would be affected by transit time. This may explain why ASL CBF is different from DSC rCBF and rCBV. The decreased DSC Tmax value may suggest high vascularity in a tumor.
• DOI: info:doi/10.2152/jmi.63.175; https://doi.org/info:doi/10.2152/jmi.63.175
• Persistent ID (NDL): info:ndljp/pid/10211167; https://dl.ndl.go.jp/pid/10211167
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2016-11-02T12:02:18+09:00
• Format (IMT): application/pdf
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Periodical Title (URI): http://repo.lib.tokushima-u.ac.jp/111177
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp

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2019-09-09 再収集