Blue Light from Dental Resin Curing Unit Causes Light-Induced Vasoconstriction in Isolated Rat Aorta

• Material Type: 博士論文
• Title: Blue Light from Dental Resin Curing Unit Causes Light-Induced Vasoconstriction in Isolated Rat Aorta
• Author/Editor: 岩田, 将; Iwata, Sho
• Author Heading: 岩田, 将; Iwata, Sho
• Publication Date: 2016-03-17
• Publication Date (W3CDTF): 2016-03-17
• Alternative Title: 歯科用レジン照射器による青色光は摘出ラット大動脈に対して光誘導性血管収縮を誘導す
• Degree grantor/type: 神奈川歯科大学
• Date Granted: 2016-03-17
• Date Granted (W3CDTF): 2016-03-17
• Dissertation Number: 甲第479号
• Degree Type: 博士（臨床歯学）
• Conferring No. (Dissertation): 甲第479号
• Text Language Code: eng
• Subject Heading: Reactive oxygen species; Dental curing lights; Vasoconstriction; Antioxidant
• Target Audience: 一般
• Note (General): 2015; application/pdf; Aims: Currently, the blue light of resin curing unit is frequently used in dental treatment. However, the influence of the blue light irradiation on oral tissue is not lear. The aim of this study was to elucidate the effect of dental blue light irradiation on vascular smooth muscle.Methods: Isolated rat descending aorta was suspended in a superfusion chamber nd superfused continuously with Krebs-Ringer solution. The changes in isometric orce of blue light irradiation were assessed using vessel strips superfused with the Krebs-Ringer solution alone or the Krebs-Ringer solutions containing 10 µM hentolamine, 100 mM dimethyl sulfoxide, 10 unit/mL superoxide dismutase, or 5 M L-histidine. The reactive oxygen species (ROS) scavenging activity of antioxidants was examined using the electron spin resonance technique espectively.Results: We first demonstrated that the vasoconstriction was induced by irradiated of blue light using dental resin curing unit. The vasoconstriction was inhibited by ncluding in the Krebs-Ringer solution an α-receptor blocker that inhibits the eurotransmitter. This phenomenon was controlled with the addition of ROS cavengers.Conclusions: Blue light irradiation of multiple times in dental treatment might have the potential to accelerate aging of pulpal blood vessel from ischemia through dental pulp vasoconstriction via ROS generation. In addition, prolonged and/or repeated blue light irradiation could cause ROS-induced oxidative stress such as ischemia-reperfusion injury on pulpal blood vessel. Therefore, preintake of ntioxidants is suggested to avoid effects such as aging of dental pulp due to blue light irradiation-induced ROS in dental clinic treatments.; Oral Health and Dental Management, 13(4):1147-1151, 2014. doi: 10.4172/2247-2452.1000745; OMICS
• Persistent ID (NDL): info:ndljp/pid/10211214; https://dl.ndl.go.jp/pid/10211214
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2016-11-02T12:02:18+09:00
• Date Created (W3CDTF): 2016-07-05
• Format (IMT): application/pdf
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Original Material (URI): Oral Health and Dental Management, 13(4):1147-1151, 2014. doi: 10.4172/2247-2452.1000745; https://www.omicsonline.org/archive/ohdm-volume-13-issue-4-year-2014.html
• Periodical Title (URI): https://kdu.repo.nii.ac.jp/records/945
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp

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