Transgenic rat models for mutagenesis and carcinogenesis
Available in National Diet Library
Find on the publisher's website
NDL Digital Collections
Digital data available
Check on the publisher's website
DOI[10.1186/s41021-016-0072-6]to the data of the same series
Holdings of Libraries in Japan
This page shows libraries in Japan other than the National Diet Library that hold the material.
Please contact your local library for information on how to use materials or whether it is possible to request materials from the holding libraries.
other
CiNii Research
Search ServicePaperYou can check the holdings of institutions and databases with which CiNii Research is linked at the site of CiNii Research.CiNii Research
Search ServiceDigitalYou can check the holdings of institutions and databases with which CiNii Research is linked at the site of CiNii Research.
Bibliographic Record
You can check the details of this material, its authority (keywords that refer to materials on the same subject, author's name, etc.), etc.
- Material Type
- 記事
- Author/Editor
- Takehiko NohmiKenichi MasumuraNaomi Toyoda-Hokaiwado
- Publication, Distribution, etc.
- Publication Date
- 2017-02-01
- Publication Date (W3CDTF)
- 2017-02-01
- Periodical title
- Genes and environment
- No. or year of volume/issue
- 39(11)
- Volume
- 39(11)
- ISSN (Periodical Title)
- 1880-7062
- ISSN-L (Periodical Title)
- 1880-7046
- Text Language Code
- eng
- DOI
- 10.1186/s41021-016-0072-6
- Persistent ID (NDL)
- info:ndljp/pid/10349119
- Collection
- Collection (Materials For Handicapped People:1)
- Collection (particular)
- 国立国会図書館デジタルコレクション > 電子書籍・電子雑誌 > その他
- Acquisition Basis
- オンライン資料収集制度
- Date Accepted (W3CDTF)
- 2017-05-11T11:41:31+09:00
- Date Captured (W3CDTF)
- 2017-05-10
- Format (IMT)
- application/pdf
- Access Restrictions
- 国立国会図書館内限定公開
- Service for the Digitized Contents Transmission Service
- 図書館・個人送信対象外
- Availability of remote photoduplication service
- 可
- Periodical Title (URI)
- Periodical Title (Persistent ID (NDL))
- info:ndljp/pid/10265750
- Data Provider (Database)
- 国立国会図書館 : 国立国会図書館デジタルコレクション
- Summary, etc.
- コレクション : 国立国会図書館デジタルコレクション > 電子書籍・電子雑誌 > その他
- DOI
- 10.1186/s41021-016-0072-6
- Access Restrictions
- インターネット公開
- Related Material (URI)
- Is Referenced By
- Quantitative analysis of mutagenicity and carcinogenicity of 2-amino-3-methylimidazo[4,5-f]quinoline in F344 gpt delta transgenic ratsIn vivo positive mutagenicity of 1,4-dioxane and quantitative analysis of its mutagenicity and carcinogenicity in ratsThresholds of Genotoxic and Non-Genotoxic CarcinogensDNA polymerase kappa counteracts inflammation‐induced mutagenesis in multiple organs of miceLimited ability of DNA polymerase kappa to suppress benzo[<i>a</i>]pyrene‐induced genotoxicity in vivoDNA Adductome Analysis Identifies <i>N</i> -Nitrosopiperidine Involved in the Etiology of Esophageal Cancer in Cixian, ChinaOxidative-stress-driven mutagenesis in the small intestine of the gpt delta mouse induced by oral administration of potassium bromateChange over time of the mutagenicity in the lungs of gpt delta transgenic mice by extract of airborne particles collected from ambient air in the Tokyo metropolitan area
- References
- Generation of Knockout Rats with X-Linked Severe Combined Immunodeficiency (X-SCID) Using Zinc-Finger NucleasesRole of p53 in the Progression from Ochratoxin A-Induced DNA Damage to Gene Mutations in the Kidneys of MicePossible involvement of genotoxic mechanisms in estragole-induced hepatocarcinogenesis in ratsA new colon and mammary carcinogen in cooked food, 2-amino-1-methyl-6-phenylimidazo[4,5-<i>b</i>]pyridine (PhIP)Mutagenicity of 2-amino-3-methylimidazo[4,5-f]quinoline in colon and liver of Big Blue rats: role of DNA adducts, strand breaks, DNA repair and oxidative stress50 years of protein acetylation: from gene regulation to epigenetics, metabolism and beyondInterpretation of mutational spectra from different genes: analyses of PhIP-induced mutational specificity in the lacI and cII transgenes from colon of Big Blue® rats<i>In vivo</i> mutagenicity and initiation following oxidative DNA lesion in the kidneys of rats given potassium bromateEnhancing effect of various hepatocarcinogens on induction of preneoplastic glutathione S-transferase placental form positive foci in rats—an approach for a new medium-term bioassay systemInsulin, Insulin-Like Growth Factors and Colon Cancer: A Review of the EvidenceEffects of dietary conjugated linoleic acid on DNA adduct formation of PhIP and IQ after bolus administration to female F344 ratsCombined application of comprehensive analysis for DNA modification and reporter gene mutation assay to evaluate kidneys of gpt delta rats given madder color or its constituentsCell cycle progression, but not genotoxic activity, mainly contributes to citrinin-induced renal carcinogenesisGenotoxicity of phenacetin in the kidney and liver of Sprague-Dawley gpt delta transgenic rats in 26-week and 52-week repeated-dose studiesAcrylamide genotoxicity in young versus adult gpt delta male ratsOchratoxin A induces DNA double-strand breaks and large deletion mutations in the carcinogenic target site of gpt delta ratsIntegration of In Vivo Genotoxicity and Short-term Carcinogenicity Assays Using F344 gpt Delta Transgenic Rats: In Vivo Mutagenicity of 2,4-Diaminotoluene and 2,6-Diaminotoluene Structural IsomersTransgenic rats carrying human c-Ha-ras proto-oncogenes are highly susceptible to N-methyl-N-nitrosourea mammary carcinogenesisNovel transgenic rat for in vivo genotoxicity assays using 6‐thioguanine and Spi<sup>−</sup> selectionOverview From the International Conference on Long-Term Tamoxifen Therapy for Breast CancerSalmonella mutagenicity tests: IV. Results from the testing of 300 chemicalsComparison of mutant frequencies and types of mutations induced by thiotepa in the endogenous Hprt gene and transgenic lacI gene of Big Blue® ratsDietary effects of soy isoflavones daidzein and genistein on 7,12-dimethylbenz[a]anthracene-induced mammary mutagenesis and carcinogenesis in ovariectomized Big Blue(R) transgenic ratsHepatic gene mutations induced in Big Blue? rats by both the potent rat liver Azo-carcinogen 6BT and its reported noncarcinogenic analogue 5BTEvaluation of the genotoxicity of tamoxifen in the liver and kidney of F344 gpt delta transgenic rat in 3-week and 13-week repeated dose studiesSite-Specific In Vivo Mutagenicity in the Kidney of gpt Delta Rats Given a Carcinogenic Dose of Ochratoxin AIn Vivo Genotoxicity of Methyleugenol in gpt Delta Transgenic Rats Following Medium-Term ExposureShort-term dosing of α-hydroxytamoxifen results in DNA damage but does not lead to liver tumours in female Wistar/Han ratsRecent advances in the protocols of transgenic mouse mutation assaysSucrose, glucose and fructose have similar genotoxicity in the rat colon and affect the metabolomeTris(2,3-dibromopropyl)phosphate causes a gradient of mutations in the cortex and outer and inner medullas of the kidney oflacI transgenic ratsOccupational and Environmental Exposures and Cancers in Developing CountriesAssessment of the mutagenic potential of Cr(VI) in the oral mucosa of Big Blue<sup>®</sup> transgenic F344 ratsIdentification of Catechol and Hydroquinone Metabolites of 4-MonochlorobiphenylHealth Effects of Exposure to Diesel Exhaust ParticlesMutational analysis of the liver, colon and kidney of Big Blue(R) rats treated with 2-amino-3-methylimidazo[4,5-f]quinolineMetabolism, disposition, and mutagenicity of 2,6-diaminotoluene, a mutagenic noncarcinogen.Absence of in vivo genotoxicity of 3-monochloropropane-1,2-diol and associated fatty acid esters in a 4-week comprehensive toxicity study using F344 gpt delta ratsValidation study of the combined repeated‐dose toxicity and genotoxicity assay using <i>gpt</i> delta ratsConnexin 32 dominant-negative mutant transgenic rats are resistant to hepatic damage by chemicalsModulation of 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine-Induced Mutation in the Cecum and Colon of Big Blue Rats by Conjugated Linoleic Acid and 1,2-Dithiole-3-ThioneKnockout Rats via Embryo Microinjection of Zinc-Finger NucleasesMutagenicity of the potent rat hepatocarcinogen 6BT to the liver of transgenic (<i>lacI</i>) rats: consideration of a reduced mutation assay protocolTamoxifen mutagenesis and carcinogenesis in livers of lambda/lacI transgenic rats: selective influence of phenobarbital promotionEndogenous estrogen status, but not genistein supplementation, modulates 7,12-dimethylbenz[a]anthracene-induced mutation in the livercII gene of transgenic big blue ratsExtent of CpG methylation is not proportional to the in vivo spontaneous mutation frequency at transgenic loci in Big Blue™ rodentsTumorigenicity of citrinin in male F344 ratsMutagenicity and carcinogenicity in relation to DNA adduct formation in rats fed leucomalachite greenTissue-specific microRNA responses in rats treated with mutagenic and carcinogenic doses of aristolochic acidA robust method for assessing chemically induced mutagenic effects in the oral cavity of transgenic Big Blue® ratsIn vivo mutational analysis of liver DNA in <i>gpt</i> delta transgenic rats treated with the hepatocarcinogens <i>N</i>‐nitrosopyrrolidine, 2‐amino‐3‐methylimidazo[4,5‐<i>f</i>]quinoline, and di(2‐ethylhexyl)phthalateSex‐specific induction of mutations by PhIP in the kidney of male and female rats and its modulation by conjugated linoleic acidMutagenesis by asbestos in the lung of λ-lacI transgenic ratsMutagenesis by man-made mineral fibres in the lung of ratsp53 +/- Hemizygous Knockout Mouse: Overview of Available DataLack of mutagenic and toxic effects of low dose potassium bromate on kidneys in the Big Blue rat<i>Gpx2</i> Is an Overexpressed Gene in Rat Breast Cancers Induced by Three Different Chemical CarcinogensCarcinogenicity of malachite green chloride and leucomalachite green in B6C3F1 mice and F344 ratsDifferential mutagenicity of riddelliine in liver endothelial and parenchymal cells of transgenic big blue rats4-Monochlorobiphenyl (PCB3) induces mutations in the livers of transgenic Fisher 344 rats17 ?-estradiol and not genistein modulateslacI mutant frequency and types of mutation induced in the heart of ovariectomized big blue rats treated with 7, 12-dimethylbenz[a]anthraceneCharacterizing Benzo[a]pyrene-induced lacZ mutation spectrum in transgenic mice using next-generation sequencingMammary Carcinomas Induced in Human c‐Ha‐<i>ras</i> Proto‐oncogene Transgenic Rats Are Estrogen‐independent, but Responsive to <i>d</i>‐Limonene TreatmentEffects of gender and species on spectra of mutation induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in the lacI transgeneMutations induced by carcinogenic doses of aristolochic acid in kidney of Big Blue transgenic ratsMutagenicity of TCDD in Big Blue® transgenic ratsAnalysis of mutations and bone marrow micronuclei in Big Blue® rats fed leucomalachite greenRelative oral bioavailability of 3-MCPD from 3-MCPD fatty acid esters in ratsEffect of Increased Intake of Dietary Animal Fat and Fat Energy on Oxidative Damage, Mutation Frequency, DNA Adduct Level and DNA Repair in Rat Colon and LiverChromatin replication and epigenome maintenanceInduction of kidney and liver cancers by the natural food additive madder color in a two-year rat carcinogenicity studyEffects of p53 knockout on ochratoxin A-induced genotoxicity in p53-deficient gpt delta miceDuctal origin of pancreatic adenocarcinomas induced by conditional activation of a human Ha- ras oncogene in rat pancreasGenotoxicity of furan in Big Blue ratsDNA damage in lung after oral exposure to diesel exhaust particles in Big Blue® ratsMutations induced by 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine (PhIP) in cecum and proximal and distal colon of lacI transgenic ratsProtective effects of citrus nobiletin and auraptene in transgenic rats developing adenocarcinoma of the prostate (TRAP) and human prostate carcinoma cellsPreferential induction of guanine deletion at 5′-GGGA-3′ in rat mammary glands by 2-amino- 1-methyl-6-phenylimidazo[4,5-b]pyridineSucrose and IQ induced mutations in rat colon by independent mechanismIncrease in mutation frequency in lung of Big Blue(R) rat by exposure to diesel exhaustDNA adduct formation and molecular analysis of in vivo lacI mutations in the mammary tissue of Big Blue(R) rats treated with 7,12-dimethylbenz[a]anthraceneGeneration of Site-Specific Mutations in the Rat Genome Via CRISPR/Cas9The Mutagenic Potential of Duodenoesophageal RefluxMutations Induced by the Carcinogenic Pyrrolizidine Alkaloid Riddelliine in the Liver <i>cII</i> <b>Gene of Transgenic Big Blue Rats</b>The Dietary Charred Meat Carcinogen 2-Amino-1-Methyl-6-Phenylimidazo[4,5-<i>b</i>]Pyridine Acts as Both a Tumor Initiator and Promoter in the Rat Ventral ProstateNo-effect level in the mutagenic activity of the drug cyproterone acetate in rat liverEffect of gamma radiation at high- and low-dose rate on a novel <i>in vivo</i> mutation assay in mouse intestinePossible participation of oxidative stress in causation of cell proliferation and in vivo mutagenicity in kidneys of gpt delta rats treated with potassium bromateBenzo[a]pyrene-enhanced mutagenesis by asbestos in the lung of λ-lacI transgenic ratsEffect of conjugated linoleic acid on the formation of spontaneous and PhIP-induced mutation in the colon and cecum of ratsOrgan differences in the enhancing potential of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine on carcinogenicity in the prostate, colon and pancreasMammary carcinogenesis and molecular analysis of in vivo cII gene mutations in the mammary tissue of female transgenic rats treated with the environmental pollutant 6-nitrochryseneBoth Early and Late Stages of Hepatocarcinogenesis Are Enhanced in Cx32 Dominant Negative Mutant Transgenic Rats with Disrupted Gap Junctional Intercellular CommunicationInhibition of prostate carcinogenesis in probasin/SV40 T antigen transgenic rats by leuprorelin, a luteinizing hormone–releasing hormone agonistMutagenicity of comfrey (Symphytum Officinale) in rat liverChemoprotection Against N-Nitrosomethylbenzylamine-Induced Mutation in the Rat EsophagusThe Effect of Dietary Restriction on PhIP-Induced Mutation in the Distal Colon and B[a]P- and ENU-Induced Mutation in the Liver of the RatCarcinogens are Mutagens: A Simple Test System Combining Liver Homogenates for Activation and Bacteria for DetectionDose Dependent Induction of DNA Adducts, Gene Mutations, and Cell Proliferation by the Antiandrogenic Drug Cyproterone Acetate in Rat LiverDNA adduct formation and mutation induction by aristolochic acid in rat kidney and liverTransgenic Disruption of Gap Junctional Intercellular Communication Enhances Early but Not Late Stage Hepatocarcinogenesis in the RatEffects of Daidzein, Genistein, and 17β-Estradiol on 7,12-Dimethylbenz[a]anthracene-Induced Mutagenicity and Uterine Dysplasia in Ovariectomized RatsAge‐dependent histopathological findings in the prostate of probasin/SV40 T antigen transgenic rats: Lack of influence of carcinogen or testosterone treatmentPotassium bromate treatment predominantly causes large deletions, but not GC > TA transversion in human cellsDetection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals: discussion.Tissue-specific mutagenesis by N-butyl-N-(4-hydroxybutyl)nitrosamine as the basis for urothelial carcinogenesisThreshold effects in genetic toxicity: perspective of chemicals regulation in GermanyThe genetic toxicity of human carcinogens and its implicationsA 13-week repeated dose study of three 3-monochloropropane-1,2-diol fatty acid esters in F344 ratsMutagenicity of 3-methylcholanthrene, PCB3, and 4-OH-PCB3 in the lung of transgenic BigBlue® ratsRat, but not human, sulfotransferase activates a tamoxifen metabolite to produce DNA adducts and gene mutations in bacteria and mammalian cells in cultureNo-Observed Effect Levels for Carcinogenicity and for in vivo Mutagenicity of a Genotoxic CarcinogenGene‐ and tissue‐specificity of mutation in Big Blue® rats treated with the hepatocarcinogen <i>N</i>‐hydroxy‐2‐acetylaminofluorene†Mutation induction by mechanical irritation caused by uracil-induced urolithiasis in Big Blue® ratsSusceptibility of Rats to Mammary Gland Carcinogenesis by the Food-Derived Carcinogen 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine (PhIP) Varies with Age and Is Associated with the Induction of Differential Gene ExpressionTamoxifen induces G:C->T:A mutations in the cII gene in the liver of lambda/lacI transgenic rats but not at 5'-CpG-3' dinucleotide sequences as found in the lacI transgeneMutational specificity: Mutational spectra of tamoxifen-induced mutations in the livers oflacl transgenic ratsMutant frequency and molecular analysis of in vivolacI mutations in the bone marrow of Big Blue� rats treated with 7,12-dimethylbenz[a]anthraceneSalmonella Mutagenicity tests: III. Results from the testing of 255 chemicalsQuantitative dose–response analysis of ethyl methanesulfonate genotoxicity in adult <i>gpt</i>‐delta transgenic miceBenzo[a]pyrene-enhanced mutagenesis by man-made mineral fibres in the lung of λ-lacI transgenic ratsMutagenicity and DNA adduct formation by aristolochic acid in the spleen of Big Blue® ratsHepatic lacI and cII mutation in transgenic (λLIZ) rats treated with dimethylnitrosamineThe use of shuttle vectors for mutation analysis in transgenic mice and ratsTransgenic rats carrying copies of the human c-Ha- ras proto-oncogene exhibit enhanced susceptibility to N -butyl- N -(4-hydroxybutyl)nitrosamine bladder carcinogenesisDevelopment of a rat cell line containing stably integrated copies of a lambda/lacI shuttle vectorEfficient rescue of integrated shuttle vectors from transgenic mice: a model for studying mutations in vivo.Studies on mammary carcinogenesis induced by a heterocyclic amine, 2‐amino‐1‐methyl‐6‐phenylimidazo[4,5‐<i>b</i>]pyridine, in mice and ratsHigh Dietary Intake of Sodium Selenite Does Not Affect Gene Mutation Frequency in Rat Colon and LiverTransgenic Rats Carrying Human c‐Ha‐<i>ras</i> Proto‐oncogene Are Highly Susceptible to N‐Nitrosomethylbenzylamine Induction of Esophageal TumorigenesisMutagenicity testing for chemical risk assessment: update of the WHO/IPCS Harmonized SchemeCarcinogenic activity of analogs of p-dimethylaminoazobenzene. VI. Activity of the benzimidazole and benzthiazole analogsOther transgenic mutation assays: A new transgenic mouse mutagenesis test system using Spi− and 6-thioguanine selectionsSite-specific cell proliferation in renal tubular cells by the renal tubular carcinogen tris(2,3-dibromopropyl)phosphate.Nickel subsulfide is genotoxic in vitro but shows no mutagenic potential in respiratory tract tissues of BigBlue™ rats and Muta™Mouse mice in vivo after inhalationAnalysis of genetic instability during mammary tumor progression using a novel selection-based assay for in vivo mutations in a bacteriophage lambda transgene target.Bromate induces loss of heterozygosity in the Thymidine kinase gene of L5178Y/Tk+/−-3.7.2C mouse lymphoma cellsGenotoxic effects of bitumen fumes in Big Blue® transgenic rat lungComparison of in vivo mutagenesis in the endogenous Hprt gene and the lacI transgene of Big Blue® rats treated with 7,12-dimethylbenz[a]anthraceneDoes tamoxifen cause cancer in humans?The dioxin TCDD protects against aflatoxin-induced mutation in female rats, but not in male ratsSpi? selection: An efficient method to detect ?-ray-induced deletions in transgenic miceComparison of <i>hprt</i> and <i>lacI</i> mutant frequency with DNA adduct formation in <i>N</i>‐hydroxy‐2‐acetylaminofluorene–treated Big Blue® rats†Quantitative approaches for assessing dose–response relationships in genetic toxicology studiesCarcinogenicity of 2,3,7,8‐tetrachlorodibenzo‐<i>p</i>‐dioxin in experimental modelsCarcinogenicity in rats of a mutagenic compound, 2-amino-3,8-dimethylimidazo[4,5-<i>f</i>]quinoxalineComparisons between carcinogenic potency and mutagenic potency to Salmonell in a series of derivatives of 4-dimethylaminozobenzene (DAB)Induction of lacI mutations in Big Blue rats treated with tamoxifen and α-hydroxytamoxifenLiver Tumors and Steroid Hormones in Rats and MiceRelationship of Carcinogenicity and Cellular Proliferation Induced by Mutagenic Noncarcinogens vs Carcinogens III. Organophosphate Pesticides vs Tris(2,3-dibromopropyl)phosphateAn animal model of preclinical diagnosis of pancreatic ductal adenocarcinomasToward a molecular equivalent dose: Use of the medaka model in comparative risk assessmentSpecies-specific differences in hepatic mutant frequency and mutational spectrum among lambda/<i>lacl</i> transgenic rats and mice following exposure to aflatoxin B<sub>1</sub>Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogensSignatures of mutational processes in human cancerA mammalian spot test: Induction of genetic alterations in pigment cells of mouse embryos with X-rays and chemical mutagensProduction of p53 gene knockout rats by homologous recombination in embryonic stem cellsSpectra of spontaneous and mutagen-induced mutations in the lacI gene in transgenic mice.The Genotoxicity of Acrylamide and Glycidamide in Big Blue RatsMutations induced by alpha-hydroxytamoxifen in the lacI and cII genes of Big Blue transgenic ratsDevelopment of a Medium-term Animal Model Using gpt Delta Rats to Evaluate Chemical Carcinogenicity and GenotoxicityEvaluation of the in vivo Mutagenicity of Nickel Subsulfide in the Lung of F344 gpt delta Transgenic Rats Exposed by Intratracheal Instillation: A Collaborative Study for the gpt delta Transgenic Rat Mutation AssayNovel DNA Polymerases and Novel Genotoxicity AssaysSpontaneous and Induced gpt and Spi− Mutant Frequencies in gpt delta Transgenic RodentsPast, present and future directions of gpt delta rodent gene mutation assaysEvaluation of In Vivo Mutagenicity by 2,4-Diaminotoluene and 2,6-Diaminotoluene in Liver of F344 gpt delta Transgenic Rat Dosed for 28 Days : A Collaborative Study of the gpt delta Transgenic Rat Mutation AssayEvaluation of the Genotoxicity of Aristolochic Acid in the Kidney and Liver of F344 gpt delta Transgenic Rat Using a 28-Day Repeated-dose Protocol: A Collaborative Study of the gpt delta Transgenic Rat Mutation AssayAdditional file 2: of Estimation of the frequency of inherited germline mutations by whole exome sequencing in ethyl nitrosourea-treated and untreated gpt delta miceGenomic integration of lambda EG10 transgene in gpt delta transgenic rodentsEstimation of the frequency of inherited germline mutations by whole exome sequencing in ethyl nitrosourea-treated and untreated gpt delta mice
- Data Provider (Database)
- 国立情報学研究所 : CiNii Research
- Original Data Provider (Database)
- 雑誌記事索引データベースCrossref科学研究費助成事業データベース科学研究費助成事業データベースCrossrefCrossrefCrossrefCrossrefCrossrefCrossrefCrossrefCrossref
- Bibliographic ID (NDL)
- 10349119