Predictive factors of uterine movement during definitive radiotherapy for cervical cancer

• Material Type: 博士論文
• ISSN: 0449-3060
• Title: Predictive factors of uterine movement during definitive radiotherapy for cervical cancer
• Author/Editor: 前本, 均; Maemoto, Hitoshi
• Author Heading: 前本, 均; Maemoto, Hitoshi
• Publication, Distribution, etc.: University of the Ryukyus
• Publication Date: 2016-10-15
• Publication Date (W3CDTF): 2016-10-15
• Alternative Title: 子宮頸癌根治的放射線治療期間中の子宮移動の予測因子について
• Periodical title: Journal of Radiation Research
• Degree grantor/type: 琉球大学
• Date Granted: 2017-03-24
• Date Granted (W3CDTF): 2017-03-24
• Dissertation Number: 甲第456号
• Degree Type: 博士(医学)
• Conferring No. (Dissertation): 医研第456号
• Text Language Code: eng
• Subject Heading: cervical cancer; radiotherapy; computed tomography; uterus; cone-beam CT
• Target Audience: 一般
• Note (General): To determine the predictive factors affecting uterine movement during radiotherapy (RT), we quantified interfraction<br/>uterine movement using computed tomography (CT) and cone-beam CT (CBCT). A total of 38 patients<br/>who underwent definitive RT for cervical cancer were retrospectively analyzed. We compared pre-RT planning CT<br/>(n = 38) and intratreatment CBCT (n = 315), measuring cervical and corporal movement in each direction. Correlations between uterine movement and volume changes of the bladder and rectum on all CBCT scans were<br/>analyzed using Spearman rank correlation analysis. Relationships between the mean uterine movement and patient<br/>factors were analyzed using the Mann–Whitney test. The mean corpus movement was: superior margin (cranio–<br/>caudal direction), 7.6 ± 5.9 mm; anterior margin (anteroposterior direction), 8.3 ± 6.3 mm; left margin (lateral direction),<br/>3.3 ± 2.9mm; and right margin (lateral direction), 3.0 ± 2.3 mm. Generally, the mean values for cervical<br/>movement were smaller than those for the corpus. There was a significant, weak correlation between changes in<br/>bladder volume and the movement of the superior margin of the corpus (ρ = 0.364, P < 0.001). There was a significant<br/>difference in movement of the superior margin of the corpus between the subgroups with and without a<br/>history of previous pelvic surgery (P = 0.007). In conclusion, change in bladder volume and a history of previous<br/>surgery were significantly related to intrafractional corpus movement; however, our observations suggest that the<br/>accurate prediction of uterine movement remains challenging.; 学位論文
• DOI: info:doi/10.1093/jrr/rrw101; https://doi.org/info:doi/10.1093/jrr/rrw101
• Persistent ID (NDL): info:ndljp/pid/10370587; https://dl.ndl.go.jp/pid/10370587
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2017-07-03T04:10:06+09:00
• Format (IMT): application/pdf
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Periodical Title (URI): http://hdl.handle.net/20.500.12000/36587; https://u-ryukyu.repo.nii.ac.jp/records/2008580
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp

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