High-Resolution Three-Dimensional Computed Tomography Analysis of the Clinical Efficacy of Cultured Autogenous Periosteal Cells in Sinus Lift Bone Grafting

• Material Type: 博士論文
• Title: High-Resolution Three-Dimensional Computed Tomography Analysis of the Clinical Efficacy of Cultured Autogenous Periosteal Cells in Sinus Lift Bone Grafting
• Author/Editor: Ogawa, Shin
• Publication, Distribution, etc.: 新潟大学
• Publication Date: 2016-09-20
• Publication Date (W3CDTF): 2016-09-20
• Alternative Title: High-Resolution Three-Dimensional Computed Tomography Analysis of the Clinical Efficacy of Cultured Autogenous Periosteal Cells in Sinus Lift Bone Grafting; 上顎洞底挙上術における培養骨膜細胞の臨床的有効性の高解像度三次元的CT分析
• Degree grantor/type: 新潟大学
• Date Granted: 2016-09-20
• Date Granted (W3CDTF): 2016-09-20
• Dissertation Number: 乙第2203号
• Degree Type: 博士（学術）
• Conferring No. (Dissertation): 乙第2203号
• Text Language Code: eng
• Subject Heading: cultured autogenous periosteal cell; sinus lift bone augmentation; three-dimensional computed tomography
• Note (General): Background and Purpose: Sinus lift (SL) using cultured autogenous periosteal cells (CAPCs) combined with autogenous bone and platelet-rich plasma (PRP) was performed to evaluate the effect of cell administration on bone regeneration, by using high-resolution three-dimensional computed tomography (CT).Materials andMethods: SL with autogenous bone and PRP plus CAPC [CAPC(+)SL] was performed in 23 patients. A piece of periosteum taken from the mandible was cultured in M199 medium with 10% fetal bovine serum (FBS) for 6 weeks. As control, 16 patients received SL with autogenous bone and PRP [CAPC(−)SL]. Three-dimensional CT imaging was performed before and 4 months and 1 year after SL, and stratification was performed based on CT numbers (HUs) corresponding to soft tissue and cancellous or cortical bone. Results: The augmented bone in CAPC(+)SL revealed an increase in HUs corresponding to cancellous bone as well as a decrease in HUs corresponding to grafted cortical bone. In addition,HUs corresponding to cancellous bone in the graft bed were increased in CAPC(+)SL but were decreased in CAPC(−)SL. Insertion torque during implant placement was significantly higher in CAPC(+)SL. Conclusion: By promoting bone anabolic activity both in augmented bone and graft bed, CAPCs are expected to aid primary fixation and osseointegration of implants in clinical applications.; 学位の種類: 博士（学術）. 報告番号: 乙第2203号. 学位記番号: 新大博（学）乙第74号. 学位授与年月日: 平成28年9月20日; Clin Implant Dent Relat Res. 2016 Aug;18(4):707-16; 新大博（学）乙第74号; 元資料の権利情報 : © 2015 Wiley Periodicals, Inc
• DOI: info:doi/10.1111/cid.12356; https://doi.org/info:doi/10.1111/cid.12356
• Persistent ID (NDL): info:ndljp/pid/10981419; https://dl.ndl.go.jp/pid/10981419
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• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2017-11-03T04:45:49+09:00
• Date Created (W3CDTF): 2019-08-05
• Format (IMT): application/pdf
• Access Restrictions: 国立国会図書館内限定公開
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• Periodical Title (URI): http://hdl.handle.net/10191/45126
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp