Re-evaluation of Pre-pump Arterial Pressure to Avoid Inadequate Dialysis and Hemolysis : Importance of Prepump Arterial Pressure Monitoring in Hemodialysis Patients 39 7

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Re-evaluation of Pre-pump Arterial Pressure to Avoid Inadequate Dialysis and Hemolysis : Importance of Prepump Arterial Pressure Monitoring in Hemodialysis Patients 7

Persistent ID (NDL): info:ndljp/pid/11008941

Material type: 博士論文

Author: Shibata, Erikoほか

Publisher: International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.

Publication date: 2015-05-01

Material Format: Digital

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Name of awarding university/degree: 徳島大学,博士（医学）

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Note (General)：: Pre-pump arterial pressure (PreAP) is monitored to avoid generating excessive negative pressure. National Kidney Foundation K/DOQI clinical practice g...

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Material Type: 博士論文
ISSN: 0160-564X
Title: Re-evaluation of Pre-pump Arterial Pressure to Avoid Inadequate Dialysis and Hemolysis : Importance of Prepump Arterial Pressure Monitoring in Hemodialysis Patients
Volume: 39 7
Author/Editor: Shibata, Eriko
Nagai, Kojiro
Takeuchi, Risa
Noda, Yasuhiro
Makino, Tomomi
Chikata, Yusuke
Hann, Michael
Yoshimoto, Sakiya
Ono, Hiroyuki
Ueda, Sayo
Tamaki, Masanori
Murakami, Taichi
Matsuura, Motokazu
Abe, Hideharu
Doi, Toshio
Author Heading: Shibata, Eriko
Nagai, Kojiro
Takeuchi, Risa
Noda, Yasuhiro
Makino, Tomomi
Chikata, Yusuke
Hann, Michael
Yoshimoto, Sakiya
Ono, Hiroyuki
Ueda, Sayo
Tamaki, Masanori
Murakami, Taichi
Matsuura, Motokazu
Abe, Hideharu
Doi, Toshio
Publication, Distribution, etc.: International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.
Publication Date: 2015-05-01
Publication Date (W3CDTF): 2015-05-01
Alternative Title: 至適透析や溶血回避のための血液ポンプ前の動脈圧の再評価 : 血液透析患者における血液ポンプ前の動脈圧モニタリングの重要性
Importance of pre pump arterial pres sure monitoring in hemodialysis patients
Periodical title: Artificial Organs
Degree grantor/type: 徳島大学
Date Granted: 2017-10-26
Date Granted (W3CDTF): 2017-10-26
Dissertation Number: 甲第3117号
Degree Type: 博士（医学）
Conferring No. (Dissertation): 甲第3117号
Text Language Code: eng
Subject Heading: Prepump arterial pressure
Hemolysis
pressure pillow
Dialysis
Blood flow
Vacuum monitor
Target Audience: 一般
Note (General): Pre-pump arterial pressure (PreAP) is monitored to avoid generating excessive negative pressure. National Kidney Foundation K/DOQI clinical practice guidelines for vascular access recommend that PreAP should not fall below-250 mmHg because excessive negative PreAP can lead to a decrease in the delivery of blood flow, inadequate dialysis, and hemolysis. Nonetheless, these recommendations are consistently disregarded in clinical practice and pressure sensors are often removed from the dialysis circuit.Thus far,delivered blood flow has been reported to decrease at values more negative than -150 mmHg of PreAP. These values have been analyzed by an ultrasonic flowmeter and not directly measured. Furthermore, no known group has evaluated whether PreAP-induced hemolysis occurs at a particular threshold. Therefore, the aim of this study was to clarify the importance of PreAP in the prediction of inadequate dialysis and hemolysis. By using different diameter needles, human blood samples from healthy volunteers were circulated in a closed dialysis circuit. The relationship between PreAP and delivered blood flow or PreAP and hemolysis was investigated. We also investigated the optimal value for PreAP using several empirical monitoring methods, such as a pressure pillow. Our investigation indicated that PreAP is a critical factor in the determination of delivered blood flow and hemolysis,both of which occured at pressure values more negative than -150 mmHg. With the exception of direct pressure monitoring, commonly used monitoring methods for PreAP were determined to be ineffective. We propose that the use of a vacuum monitor would permit regular measurement of PreAP.
DOI: info:doi/10.1111/aor.12448
https://doi.org/info:doi/10.1111/aor.12448
Persistent ID (NDL): info:ndljp/pid/11008941
https://dl.ndl.go.jp/pid/11008941
Collection: 障害者向け資料
Collection (Materials For Handicapped People:1): テキストデータ
Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文
https://dl.ndl.go.jp/collections/A00014
Acquisition Basis: 博士論文（自動収集）
Date Accepted (W3CDTF): 2018-01-02T17:18:43+09:00
Format (IMT): application/pdf
Access Restrictions: 国立国会図書館内限定公開
Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
Availability of remote photoduplication service: 可
Periodical Title (URI): http://repo.lib.tokushima-u.ac.jp/110961
Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション
https://dl.ndl.go.jp