EGFR Downregulation after Anti-EGFR Therapy Predicts the Antitumor Effect in Colorectal Cancer 15 10

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EGFR Downregulation after Anti-EGFR Therapy Predicts the Antitumor Effect in Colorectal Cancer 10

Persistent ID (NDL): info:ndljp/pid/11122621

Material type: 博士論文

Author: Okada, Yasuyukiほか

Publisher: American Association for Cancer Research

Publication date: 2017-07-11

Material Format: Digital

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Name of awarding university/degree: 徳島大学,博士（医学）

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Note (General)：: ABC, antibody-binding capacity; ADCC, antibody-dependent cellular cytotoxicity; ATCC, American Type Culture Collection; BSA, bovine serum albumin; CR,...

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Material Type: 博士論文
ISSN: 1541-7786
Title: EGFR Downregulation after Anti-EGFR Therapy Predicts the Antitumor Effect in Colorectal Cancer
Volume: 15 10
Author/Editor: Okada, Yasuyuki
Kimura, Tetsuo
Nakagawa, Tadahiko
Okamoto, Koichi
Fukuya, Akira
Goji, Takahiro
Fujimoto, Shota
Sogabe, Masahiro
Miyamoto, Hiroshi
Muguruma, Naoki
Tsuji, Yasushi
Okahisa, Toshiya
Takayama, Tetsuji
Author Heading: Okada, Yasuyuki
Kimura, Tetsuo
Nakagawa, Tadahiko
Okamoto, Koichi
Fukuya, Akira
Goji, Takahiro
Fujimoto, Shota
Sogabe, Masahiro
Miyamoto, Hiroshi
Muguruma, Naoki
Tsuji, Yasushi
Okahisa, Toshiya
Takayama, Tetsuji
Publication, Distribution, etc.: American Association for Cancer Research
Publication Date: 2017-07-11
Publication Date (W3CDTF): 2017-07-11
Alternative Title: 大腸癌における抗EGFR抗体薬治療後のEGFR Downregulationは抗腫瘍効果を予測する
EGFR Down-regulation Predicts anti-EGFR Response
Periodical title: Molecular Cancer Research
Degree grantor/type: 徳島大学
Date Granted: 2017-10-26
Date Granted (W3CDTF): 2017-10-26
Dissertation Number: 甲第3116号
Degree Type: 博士（医学）
Conferring No. (Dissertation): 甲第3116号
Text Language Code: eng
Subject Heading: Colorectal cancer
EGFR
cetuximab
internalization
degradation
Target Audience: 一般
Note (General): ABC, antibody-binding capacity; ADCC, antibody-dependent cellular cytotoxicity; ATCC, American Type Culture Collection; BSA, bovine serum albumin; CR, complete response; CRC, colorectal cancer; CT, computed tomography; ECACC, European Collection of Authenticated Cell Cultures; EGF, epidermal growth factor; EGFR, epidermal growth factor receptor; ETS, early tumor shrinkage; FBS, fetal bovine serum; FISH, fluorescent in situ hybridization; HRP, horseradish peroxidase; HSRRB, Health Science Research Resources Bank; IHC, immunohistochemistry; MesNa, Mercaptoethanesulfonic acid sodium; mCRC, metastatic colorectal cancer; mAb, monoclonal antibody; mAbs, monoclonal antibodies; PARP, poly (ADP-ribose) polymerase; PBS, phosphate buffered saline; PD, progressive disease; p-ERK, phosphorylated ERK; PNA-LNA, peptide nucleic acid-locked nucleic acid; PR, partial response; PVDF, polyvinylidene difluoride; RECIST, Response Evaluation Criteria in Solid Tumors; RIKEN BRC, RIKEN BioResource Center; SD, stable disease; SDS, sodium dodecyl sulfate; SDS-PAGE, SDS-polyamide gel electrophoresis; TBS-T, Tris-buffered saline with 0.1% Tween; TGF-α, transforming growth factor-α.
DOI: info:doi/10.1158/1541-7786.MCR-16-0383
https://doi.org/info:doi/10.1158/1541-7786.MCR-16-0383
Persistent ID (NDL): info:ndljp/pid/11122621
https://dl.ndl.go.jp/pid/11122621
Collection: 障害者向け資料
Collection (Materials For Handicapped People:1): テキストデータ
Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文
https://dl.ndl.go.jp/collections/A00014
Acquisition Basis: 博士論文（自動収集）
Date Accepted (W3CDTF): 2018-08-03T23:36:01+09:00
Format (IMT): application/pdf
Access Restrictions: 国立国会図書館内限定公開
Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
Availability of remote photoduplication service: 可
Periodical Title (URI): http://repo.lib.tokushima-u.ac.jp/110960
Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション
https://dl.ndl.go.jp