Relationship between renal function and serum magnesium concentration in elderly outpatients treated with magnesium oxide

• Material Type: 博士論文
• Title: Relationship between renal function and serum magnesium concentration in elderly outpatients treated with magnesium oxide
• Author/Editor: Horibata, Ken
• Author Heading: Horibata, Ken
• Publication, Distribution, etc.: 三重大学
• Publication Date: 2018-07-18
• Publication Date (W3CDTF): 2018-07-18
• Alternative Title: 酸化マグネシウム内服中の高齢外来患者における腎機能と血清マグネシウム濃度の関係
• Degree grantor/type: 三重大学
• Date Granted: 2018-07-18
• Date Granted (W3CDTF): 2018-07-18
• Dissertation Number: 乙医学第1017号
• Degree Type: 博士(医学)
• Conferring No. (Dissertation): 乙医学第1017号
• Text Language Code: eng
• Alias of Author: ホリバタ, ケン; 堀端, 謙
• Subject Heading: elderly outpatients; estimated glomerular filtration rate; magnesium oxide; serum magnesium concentration
• Target Audience: 一般
• Note (General): application/pdf; AIMS: We investigated the relationship between renal function and serum magnesium concentration in elderly patients treated with magnesium oxide (MgO) in an outpatient setting of an urban hospital in Japan.METHODS: In the present study, 44 elderly outpatients (23 patients with constipation treated with daily oral MgO and 21 untreated patients in the control group) who visited Kameyama municipal medical center were enrolled. Variables were age, sex, weight, height, serum magnesium concentration, serum blood urea nitrogen level, serum creatinine level, use of other magnesium-containing supplements and symptoms associated with hypermagnesemia. We calculated the estimated glomerular filtration rate (eGFR) and classified patients based on eGFR category.RESULTS: Compared with the control group, the MgO group showed a significantly higher concentration of serum magnesium (median 2.2 mg/dL [interquartile range 2.1-2.3] vs 2.4 mg/dL [2.2-2.6], P < 0.001). Hypermagnesemia (>2.6 mg/dL) was noted only in the MgO group. However, symptoms associated with hypermagnesemia occurred in patients from both groups, with no significant difference between groups. In the MgO group, significant difference was seen in the median serum magnesium concentration between eGFR categories (P < 0.05). The category G4 (eGFR 15-29 mL/min/1.73 m(2) ) group had the highest serum magnesium concentration in the MgO group (3.0 mg/L [2.9-3.1]).CONCLUSIONS: Elderly patients treated with MgO have higher serum magnesium levels compared with the control group. MgO should be prescribed with caution in patients with low renal function as shown by a GFR category G3b or less (eGFR < 30 mL/min/1.73 m(2) ). Geriatr Gerontol Int 2016; 16: 600-605.; 本文 / Department of Internal Medicine, Kameyama Municipal Medical Center, Kameyama, Mie, Japan; 12p
• DOI: info:doi/10.1111/ggi.12530; https://doi.org/info:doi/10.1111/ggi.12530
• Persistent ID (NDL): info:ndljp/pid/11164212; https://dl.ndl.go.jp/pid/11164212
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2018-10-03T17:18:55+09:00
• Date Created (W3CDTF): 2018-09-25
• Format (IMT): application/pdf
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Periodical Title (URI): http://hdl.handle.net/10076/00017752; https://mie-u.repo.nii.ac.jp/records/12120
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp

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2023-12-15 再収集