Effect of peripherally and cortically evoked swallows on jaw reflex responses in anesthetized rabbits

• Material Type: 博士論文
• Title: Effect of peripherally and cortically evoked swallows on jaw reflex responses in anesthetized rabbits
• Author/Editor: Suzuki, Taku
• Publication, Distribution, etc.: 新潟大学
• Publication Date: 2018-09-20
• Publication Date (W3CDTF): 2018-09-20
• Alternative Title: Effect of peripherally and cortically evoked swallows on jaw reflex responses in anesthetized rabbits; 麻酔下ウサギにおいて末梢および中枢性嚥下が顎反射に及ぼす影響
• Degree grantor/type: 新潟大学
• Date Granted: 2018-09-20
• Date Granted (W3CDTF): 2018-09-20
• Dissertation Number: 甲第4504号
• Degree Type: 博士（歯学）
• Conferring No. (Dissertation): 甲第4504号
• Text Language Code: eng
• Subject Heading: Swallow; Jaw-opening reflex; Jaw-closing reflex; Superior laryngeal nerve; Cortical swallowing area; Rabbit
• Note (General): This study aimed to investigate whether the jaw-opening (JOR) and jaw-closing reflexes (JCR) are modulated during not only peripherally, but also centrally, evoked swallowing. Experiments were carried out on 24 adult male Japanese white rabbits. JORs were evoked by trigeminal stimulation at 1 Hz for 30 s. In the middle 10 s, either the superior laryngeal nerve (SLN) or cortical swallowing area (Cx) was simultaneously stimulated to evoke swallowing. The peak-to-peak JOR amplitude was reduced during the middle and late 10-s periods (i.e., during and after SLN or Cx stimulation), and the reduction was dependent on the current intensity of SLN/Cx stimulation: greater SLN/Cx stimulus current resulted in greater JOR inhibition. The reduction rate was significantly greater during Cx stimulation than during SLN stimulation. The amplitude returned to baseline 2 min after 10-s SLN/Cx stimulation. The effect of co-stimulation of SLN and Cx was significantly greater than that of SLN stimulation alone. There were no significant differences in any parameters of the JCR between conditions. These results clearly showed that JOR responses were significantly suppressed, not only during peripherally evoked swallowing but also during centrally evoked swallowing, and that the inhibitory effect is likely to be larger during centrally compared with peripherally evoked swallowing. The functional implications of these results are discussed.; 学位の種類: 博士（歯学）. 報告番号: 甲第4504号. 学位記番号: 新大院博（歯）甲第412号. 学位授与年月日: 平成30年9月20日; 新大院博（歯）甲第412号; 元資料の権利情報 : (C) 2018 Elsevier B.V. All rights reserved.
• DOI: info:doi/10.1016/j.brainres.2018.05.002; https://doi.org/info:doi/10.1016/j.brainres.2018.05.002
• Persistent ID (NDL): info:ndljp/pid/11195271; https://dl.ndl.go.jp/pid/11195271
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2018-12-03T16:15:19+09:00
• Date Created (W3CDTF): 2019-09-10
• Format (IMT): application/pdf
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Periodical Title (URI): http://hdl.handle.net/10191/50731
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp