Nature and source of animal spontaneous behaviors: Insights from psychobehavioral development and neuronal population dynamics in mice

• Material Type: 博士論文
• Title: Nature and source of animal spontaneous behaviors: Insights from psychobehavioral development and neuronal population dynamics in mice
• Author/Editor: Ray Xin, Lee
• Author Heading: Ray Xin, Lee
• Publication Date: 2018-11-30
• Publication Date (W3CDTF): 2018-11-30
• Alternative Title: 自発行動の性質と起点：マウスにおける心理行動学的発達と神経群の活動による考察
• Degree grantor/type: Okinawa Institute of Science and Technology Graduate University
• Date Granted: 2018-11-30
• Date Granted (W3CDTF): 2018-11-30
• Dissertation Number: 甲第23号
• Degree Type: Doctor of Philosophy
• Conferring No. (Dissertation): 甲第23号
• Text Language Code: eng
• Target Audience: 一般
• Note (General): Awake animals switch between different behavioral states irregularly even in a homogenous and steady environment, especially obvious outside from any behavioral task when they are free to voluntarily behave. These irregular but structured patterns have been taken as a representation of internal states such as emotion, and are believed to represent underlying background brain activity and its dynamics. To date, the nature and source of animal spontaneous behaviors remain as a major conceptual challenge to academia, due to the lack of approaches to systematically and quantitatively examine this fundamental process. To achieve insights about the neural substrate of animal spontaneous behaviors, the research was conducted in two directions: (i) To interpret previously challenging and inconclusive behavioral development by re-evaluating spontaneous behaviors that represent emotionality, centered on the study of PTSD (post-traumatic stress disorder)-like internal psychological development in laboratory mice; (ii) To demonstrate a driving and control principle explaining fine-scale and global observations of neuronal and behavioral dynamics in spontaneously behaving mice, by two-photon calcium imaging of neuronal populations across cerebral cortical layers and areas. The results from these investigations provide the first system-level view of experimentally disentangled components, processes, and determinants explaining the nature and source of animal spontaneous behaviors.
• DOI: 10.15102/1394.00000700; https://doi.org/10.15102/1394.00000700
• Persistent ID (NDL): info:ndljp/pid/11217145; https://dl.ndl.go.jp/pid/11217145
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2019-01-04T08:16:43+09:00
• Date Created (W3CDTF): 2018-12-05
• Format (IMT): application/pdf
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Periodical Title (URI): http://dx.doi.org/10.15102/1394.00000700; http://id.nii.ac.jp/1394/00000700/
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp

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2023-09-05 再収集

2023-09-05 再収集