Helicobacter pylori除菌治療は治療結果にかかわらず生活の質を改善する : 多施設共同前方視的コホート研究

• Material Type: 博士論文
• ISSN: 0025-7974
• Title: Helicobacter pylori除菌治療は治療結果にかかわらず生活の質を改善する : 多施設共同前方視的コホート研究
• Volume: 96 52
• Author/Editor: 田口, 宏樹
• Author Heading: 田口, 宏樹
• Publication, Distribution, etc.: 鹿児島大学
• Publication Date: 96 52
• Publication Date (W3CDTF): 2018-11-20
• Alternative Title: Helicobacter pylori eradication improves the quality of life regardless of the treatment outcome: A multicenter prospective cohort study.
• Periodical title: Medicine
• Degree grantor/type: 鹿児島大学
• Date Granted: 2018-11-20
• Date Granted (W3CDTF): 2018-11-20
• Dissertation Number: 甲総研第484号
• Degree Type: 博士(医学); Doctor of Philosophy in Medical Science
• Conferring No. (Dissertation): 甲総研第484号
• Text Language Code: eng
• Subject Heading: dyspepsia; epigastralgia; eradication treatment; Helicobacter pylori; mental component summary; physical component summary; quality of life
• NDC: 492
• Target Audience: 一般
• Note (General): 博士論文全文, 博士論文要旨, 最終試験結果の要旨, 論文審査の要旨; Helicobacter pylori (Hp) eradication is recommended for improving the quality of life (QOL) of patients with epigastric symptoms, especially reflux and dyspepsia. However, no reports have investigated the improvement of QOL after the eradication of Hp irrespective of epigastric symptoms. The aim of this study was to investigate the improvement in the QOL after the eradication of Hp irrespective of epigastric symptoms, and evaluate the factors associated with an improved QOL after the eradication of Hp.This prospective cohort study was performed at 15 referral institutions from September 2013 to December 2014. The patients’ QOL and epigastric symptoms were evaluated before and after the eradication of Hp using the 8-item Short-Form Health Survey (SF-8) and the modified Frequency Scale for the Symptoms of Gastroesophageal Reflux Disease, respectively.One hundred sixty-five of 184 Hp-infected patients underwent Hp eradication treatment. The treatment was successful in 82.4% (136/165) of the cases. One hundred sixty of the 165 Hp-infected patients were eligible for inclusion in the QOL analysis. In the indices of QOL on the SF-8, the scores on both the mental component summary (MCS) and the physical component summary (PCS) were found to have significantly improved after the eradication of Hp. However, the epigastric symptoms before the eradication of Hp were not correlated with either the MCS or PCS. A low QOL value before the eradication of Hp was the factor what was most strongly associated with the improvement in the QOL.The eradication of Hp improved the QOL, regardless of the outcome of the treatment, especially in patients who had an impaired QOL before the eradication.
• DOI: info:doi/10.1097/MD.0000000000009507; https://doi.org/info:doi/10.1097/MD.0000000000009507
• Persistent ID (NDL): info:ndljp/pid/11217149; https://dl.ndl.go.jp/pid/11217149
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2019-01-04T08:16:43+09:00
• Date Created (W3CDTF): 2018-12-04
• Format (IMT): PDF; application/pdf
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Periodical Title (URI): http://hdl.handle.net/10232/00030355
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp

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