Local Thickness of Epicardial Adipose Tissue Surrounding the Left Anterior Descending Artery Is a Simple Predictor of Coronary Artery Disease : New Prediction Model in Combination With Framingham Risk Score

• Material Type: 博士論文
• ISSN: 1347-4820
• Title: Local Thickness of Epicardial Adipose Tissue Surrounding the Left Anterior Descending Artery Is a Simple Predictor of Coronary Artery Disease : New Prediction Model in Combination With Framingham Risk Score
• Volume: 82 5
• Author/Editor: Gulinu, Maimaituxun; Shimabukuro, Michio; Fukuda, Daiju; Yagi, Shusuke; Hirata, Yukina; Iwase, Takashi; Takao, Shoichiro; Matsuura, Tomomi; Ise, Takayuki; Kusunose, Kenya; Tobiume, Takeshi; Yamaguchi, Koji; Yamada, Hirotsugu; Soeki, Takeshi; Wakatsuki, Tetsuzo; Harada, Masafumi; Sata, Masataka
• Author Heading: Gulinu, Maimaituxun; Shimabukuro, Michio; Fukuda, Daiju; Yagi, Shusuke; Hirata, Yukina; Iwase, Takashi; Takao, Shoichiro; Matsuura, Tomomi; Ise, Takayuki; Kusunose, Kenya; Tobiume, Takeshi; Yamaguchi, Koji; Yamada, Hirotsugu; Soeki, Takeshi; Wakatsuki, Tetsuzo; Harada, Masafumi; Sata, Masataka
• Publication, Distribution, etc.: The Japanese Circulation Society
• Publication Date: 2018-04-25
• Publication Date (W3CDTF): 2018-04-25
• Alternative Title: 左前下行枝冠動脈周囲の局所心外膜脂肪厚は簡便な冠動脈疾患の予測因子である : フラミンガムリスクスコアと組み合わせた新しい予測モデル
• Periodical title: Circulation Journal
• Degree grantor/type: 徳島大学
• Date Granted: 2018-09-27
• Date Granted (W3CDTF): 2018-09-27
• Dissertation Number: 甲第3217号
• Degree Type: 博士（医学）
• Conferring No. (Dissertation): 甲第3217号
• Text Language Code: eng
• Subject Heading: Coronary artery disease; Epicardial adipose tissue; Framingham risk score
• Target Audience: 一般
• Note (General): Background: Compared with global cardiac adiposity, the local accumulation of fat surrounding coronary arteries might have a more direct impact on coronary artery disease (CAD). Here, we compared the local epicardial adipose tissue (EAT) thickness and global cardiac adiposity volumes for predicting CAD.Methods and Results: A total of 197 consecutive subjects underwent 320-slice multi-detector computed tomography coronary angiography and were segregated into CAD (≥1 coronary artery branch stenosis ≥50%) and non-CAD groups. EAT thickness was measured at the right coronary artery (EATRCA), the left anterior descending artery (EATLAD), and the left circumflex artery (EATLCX). Although EATRCA and EATLCX were similar between the 2 groups, EATLAD was larger in the CAD group than in the non-CAD group (5.45±2.16 mm vs. 6.86±2.19 mm, P<0.001). EATLAD, after correcting for confounding factors, was strongly associated with CAD (r=0.276, P<0.001) and Gensini score (r=0.239, P<0.001). On multiple regression analysis, Framingham risk score combined with EATLAD was a strong predictor of CAD (adjusted R2=0.121; P<0.001).Conclusions: The local fat thickness surrounding the LAD is a simple and useful surrogate marker for estimating the presence, severity, and extent of CAD, independent of classical cardiovascular risk factors.
• DOI: info:doi/10.1253/circj.CJ-17-1289; https://doi.org/info:doi/10.1253/circj.CJ-17-1289
• Persistent ID (NDL): info:ndljp/pid/11278311; https://dl.ndl.go.jp/pid/11278311
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2019-05-06T10:27:56+09:00
• Format (IMT): application/pdf
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Periodical Title (URI): http://repo.lib.tokushima-u.ac.jp/112879
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp