小児・青年期におけるQT 短縮スクリーニングの暫定基準値

• Material Type: 博士論文
• Title: 小児・青年期におけるQT 短縮スクリーニングの暫定基準値
• Volume: 82 10
• Author/Editor: 櫨木, 大祐
• Author Heading: 櫨木, 大祐
• Publication, Distribution, etc.: THE JAPANESE CIRCULATION SOCIETY
• Publication Date: 2018; 82 10
• Publication Date (W3CDTF): 2018
• Alternative Title: Tentative Screening Criteria for Short QT Interval in Children and Adolescents.
• Periodical title: Circulation Journal
• Degree grantor/type: 鹿児島大学
• Date Granted: 2019-03-19
• Date Granted (W3CDTF): 2019-03-19
• Dissertation Number: 甲総研第492号
• Degree Type: 博士(医学); Doctor of Philosophy in Medical Science
• Conferring No. (Dissertation): 甲総研第492号
• Text Language Code: eng
• Subject Heading: Adolescent; Children; Screening; Short QT interval
• NDC: 492
• Target Audience: 一般
• Note (General): 博士論文本文, 博士論文要旨, 最終試験結果の要旨, 論文審査の要旨; Background: While the prevalence of short QT syndrome (SQTS) in children and adolescents is low, early detection is important because SQTS can cause life-threatening arrhythmia. The aim of this study was to determine the tentative screening criteria for short QT interval in children and adolescents.Methods and Results: A total of 75,040 digitally stored electrocardiograms (ECG) of participants in a school-based ECG screening program were obtained between 2009 and 2013 in Kagoshima, Japan. ECG with a corrected QT interval (QTc) below the 10th percentile for each grade and sex were selected: 2,581 first graders (M/F, 1,296/1,285); 2,792 7th graders (M/F, 1,400/1,392); and 2018 10th graders (M/F, 979/1,039). Three consecutive QT/RR intervals were manually measured and corrected using Bazett's formula. The prevalence of SQTS was estimated at 1/30,000–1/10,000, which was set compared with the prevalence of long QT syndrome, then the screening points of the prevalence of short QT interval were assumed to be between 1/5,000 and 1/2,000 to exclude the possibility of false negative. We obtained the following tentative criteria based on frequency distribution charts: 325, 315 and 305 ms for male 1st, 7th and 10th graders, respectively; and 320 ms for female 1st, 7th, and 10th graders.Conclusions: For primary SQTS screening of children and adolescents, the QTc values for short QT interval should be adapted according to grade and sex.
• DOI: info:doi/10.1253/circj.CJ-18-0213; https://doi.org/info:doi/10.1253/circj.CJ-18-0213
• Persistent ID (NDL): info:ndljp/pid/11279019; https://dl.ndl.go.jp/pid/11279019
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2019-05-06T10:27:56+09:00
• Date Created (W3CDTF): 2019-04-16
• Format (IMT): PDF; application/pdf
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Original Material (URI): https://www.jstage.jst.go.jp/browse/circj/-char/en
• Periodical Title (URI): http://hdl.handle.net/10232/00030529
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp

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