Clinical Features of Treated and Untreated Type 1 Idiopathic Macular Telangiectasia Without the Occurrence of Secondary Choroidal Neovascularization Followed for 2 Years in Japanese Patients

• Material Type: 博士論文
• Title: Clinical Features of Treated and Untreated Type 1 Idiopathic Macular Telangiectasia Without the Occurrence of Secondary Choroidal Neovascularization Followed for 2 Years in Japanese Patients
• Author/Editor: 逢坂, 理恵
• Author Heading: 逢坂, 理恵
• Publication Date: 2019-03-24
• Publication Date (W3CDTF): 2019-03-24
• Degree grantor/type: 香川大学
• Date Granted: 2019-03-24
• Date Granted (W3CDTF): 2019-03-24
• Dissertation Number: 甲第706号
• Degree Type: 博士（医学）
• Conferring No. (Dissertation): 甲第706号
• Text Language Code: eng
• Alias of Author: Osaka, Rie
• Subject Heading: Type 1 idiopathic macular telangiectasia; macular edema; intravitreal anti-vascular endothelial growth factor; intravitreal bevacizumab; laser photocoagulation; retinal vein occlusion; retinal macroaneurysm; vascular permeability
• Target Audience: 一般
• Note (General): Purpose: To evaluate the clinical features of Type 1 idiopathic macular telangiectasia (IMT) followed up for 2 years.; Methods: Forty-nine patients with unilateral Type 1 IMT were examined. Thirty-one IMT eyes were treated with direct laser photocoagulation and/or intravitreal bevacizumab; the remaining 18 eyes, with good vision or slight macular edema, were untreated. Changes in best-corrected visual acuity and central retinal thickness between baseline and 24 months after the initial visit were examined.; Results: Of 49 eyes, nine were treated with direct laser photocoagulation, 12 with laser photocoagulation and intravitreal bevacizumab, 10 with intravitreal bevacizumab monotherapy, whereas 18 did not receive any treatment. The mean logarithm of the minimum angle of resolution best-corrected visual acuity was 0.20 ± 0.19 (median, 20/29) and 0.13 ± 0.22 (median, 20/25) at baseline and 24 months, respectively (P = 0.023). The mean central retinal thickness was 375.0 ± 94.5 μm and 315.3 ± 78.5 μm at baseline and 24 months, respectively (P < 0.001). Retinal vein occlusion and retinal macroaneurysm occurred in six eyes and one eye, respectively, during follow-up.; Conclusion: Treatment with laser photocoagulation and/or intravitreal bevacizumab may be effective for Type 1 IMT, 36.7% of IMT eyes required no treatment over a 2-year follow-up, and other retinal vascular events were not uncommon.
• DOI: info:doi/10.1097/IAE.0000000000001724; https://doi.org/info:doi/10.1097/IAE.0000000000001724
• Persistent ID (NDL): info:ndljp/pid/11279129; https://dl.ndl.go.jp/pid/11279129
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2019-05-06T10:27:56+09:00
• Date Created (W3CDTF): 2020-10-27
• Format (IMT): PDF
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Periodical Title (URI): https://kagawa-u.repo.nii.ac.jp/records/350
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp