COMBINATION THERAPY OF INTRAVITREAL RANIBIZUMAB AND SUBTHRESHOLD MICROPULSE PHOTOCOAGULATION FOR MACULAR EDEMA SECONDARY TO BRANCH RETINAL VEIN OCCLUSION : 6-MONTH RESULT

• Material Type: 博士論文
• Title: COMBINATION THERAPY OF INTRAVITREAL RANIBIZUMAB AND SUBTHRESHOLD MICROPULSE PHOTOCOAGULATION FOR MACULAR EDEMA SECONDARY TO BRANCH RETINAL VEIN OCCLUSION : 6-MONTH RESULT
• Author/Editor: Terashima, Hiroko
• Publication, Distribution, etc.: 新潟大学
• Publication Date: 2019-03-15
• Publication Date (W3CDTF): 2019-03-15
• Alternative Title: COMBINATION THERAPY OF INTRAVITREAL RANIBIZUMAB AND SUBTHRESHOLD MICROPULSE PHOTOCOAGULATION FOR MACULAR EDEMA SECONDARY TO BRANCH RETINAL VEIN OCCLUSION : 6-MONTH RESULT; 網膜静脈分枝閉塞症の黄斑浮腫に対するラニビズマブ硝子体内注射療法とマイクロパルス閾値下凝固併用療法 : 6カ月成績
• Degree grantor/type: 新潟大学
• Date Granted: 2019-03-15
• Date Granted (W3CDTF): 2019-03-15
• Dissertation Number: 乙第2237号
• Degree Type: 博士（医学）
• Conferring No. (Dissertation): 乙第2237号
• Text Language Code: eng
• Note (General): Purpose: To determine the efficacy of the combination therapy of intravitreal ranibizumab (IVR) and 577-nm yellow laser subthreshold micropulse laser photocoagulation (SMLP) for macular edema secondary to branch retinal vein occlusion cystoid macular edema.Methods: Retrospective, consecutive, case–control study. Forty-six eyes of 46 patients with treatment-naive branch retinal vein occlusion cystoid macular edema were enrolled. The IVR + SMLP group consisted of 22 patients who had undergone both SMLP and IVR. Intravitreal ranibizumab group consisted of 24 patients who had undergone IVR monotherapy. Intravitreal ranibizumab therapy was one initial injection and on a pro re nata in both groups, and SMLP was performed at 1 month after IVR in the IVR + SMLP group. Preoperatively and monthly, best-corrected visual acuity and central retinal thickness were evaluated using swept source optical coherence tomography.Results: Best-corrected visual acuity and central retinal thickness significantly improved at 6 months in IVR + SMLP and IVR groups. Best-corrected visual acuity and central retinal thickness were not significantly different between the two groups at any time points. The number of IVR injections during initial 6 months in IVR group (2.3 ± 0.9) was significantly greater (P = 0.034) than that in IVR + SMLP group (1.9 ± 0.8).Conclusion: The combination therapy of IVR and SMLP can treat branch retinal vein occlusion cystoid macular edema effectively, by decreasing the frequency of IVR injections while maintaining good visual acuity.RETINA 0:1–8, 2018; 学位の種類: 博士（医学）. 報告番号: 乙第2237号. 学位記番号: 新大博（医）乙第1809号. 学位授与年月日: 平成31年3月15日; RETINA.2019, 39(7), 1377–1384.; 新大博（医）乙第1809号; 開始ページ : 1; 終了ページ : 8
• DOI: info:doi/10.1097/IAE.0000000000002165; https://doi.org/info:doi/10.1097/IAE.0000000000002165
• Persistent ID (NDL): info:ndljp/pid/11337432; https://dl.ndl.go.jp/pid/11337432
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2019-08-03T12:23:27+09:00
• Date Created (W3CDTF): 2019-09-10
• Format (IMT): application/pdf
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Periodical Title (URI): http://hdl.handle.net/10191/51274
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp