Correlation and Characteristics of Intravoxel Incoherent Motion and Arterial Spin Labeling Techniques Versus Multiple Parameters Obtained on Dynamic Susceptibility Contrast Perfusion MRI for Brain Tumors

• Material Type: 博士論文
• ISSN: 1349-6867
• Title: Correlation and Characteristics of Intravoxel Incoherent Motion and Arterial Spin Labeling Techniques Versus Multiple Parameters Obtained on Dynamic Susceptibility Contrast Perfusion MRI for Brain Tumors
• Volume: 66 3-4
• Author/Editor: Dolgorsuren, Enkh-Amgalan; Harada, Masafumi; Kanazawa, Yuki; Abe, Takashi; Otomo, Maki; Matsumoto, Yuki; Mizobuchi, Yoshifumi; Nakajima, Kohhei
• Author Heading: Dolgorsuren, Enkh-Amgalan; Harada, Masafumi; Kanazawa, Yuki; Abe, Takashi; Otomo, Maki; Matsumoto, Yuki; Mizobuchi, Yoshifumi; Nakajima, Kohhei
• Publication, Distribution, etc.: Tokushima University Faculty of Medicine
• Publication Date: 2019-08
• Publication Date (W3CDTF): 2019-08
• Alternative Title: 脳腫瘍におけるダイナミック磁化率コントラスト灌流MRIの各種パラメーターに対するintravoxel incoherent motion法とarterial spin labeling法との相関と特徴; Perfusion MRI for brain tumors
• Periodical title: The Journal of Medical Investigation
• Degree grantor/type: 徳島大学
• Date Granted: 2019-09-26
• Date Granted (W3CDTF): 2019-09-26
• Dissertation Number: 甲第3336号
• Degree Type: 博士（医学）
• Conferring No. (Dissertation): 甲第3336号
• Text Language Code: eng
• Subject Heading: Intravoxel incoherent motion; brain tumor; arterial spin labeling; dynamic susceptibility contrast perfusion
• Target Audience: 一般
• Note (General): Purpose : To compare data on brain tumors derived from intravoxel incoherent motion (IVIM) and arterial spin labeling (ASL) imaging with multiple parameters obtained on dynamic susceptibility contrast (DSC) perfusion MRI and to clarify the characteristics of IVIM and ASL perfusion data from the viewpoint of cerebral blood flow (CBF) analysis. Methods : ASL-CBF and IVIM techniques as well as DSC examination were performed in 24 patients with brain tumors. The IVIM data were analyzed with the two models. The relative blood flow (rBF), relative blood volume (rBV) corrected relative blood volume (crBV), mean transit time (MTT), and leakage coefficient (K2) were obtained from the DSC MRI data. Results : The ASL-CBF had the same tendency as the perfusion parameters derived from the DSC data, but the permeability from the vessels had less of an effect on the ASL-CBF. The diffusion coefficient of the fast component on IVIM contained more information on permeability than the f value. Conclusion : ASL-CBF is more suitable for the evaluation of perfusion in brain tumors than IVIM parameters. ASL-CBF and IVIM techniques should be carefully selected and the biological significance of each parameter should be understood for the correct comprehension of the pathological status of brain tumors.
• DOI: info:doi/10.2152/jmi.66.308; https://doi.org/info:doi/10.2152/jmi.66.308
• Persistent ID (NDL): info:ndljp/pid/11378273; https://dl.ndl.go.jp/pid/11378273
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2019-11-04T14:30:53+09:00
• Format (IMT): application/pdf
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Periodical Title (URI): http://repo.lib.tokushima-u.ac.jp/113793
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp