Cognitive Function and Brain Atrophy Predict Non-pharmacological Efficacy in Dementia: The Mihama-Kiho Scan Project2

• Material Type: 博士論文
• Title: Cognitive Function and Brain Atrophy Predict Non-pharmacological Efficacy in Dementia: The Mihama-Kiho Scan Project2
• Author/Editor: Tabei, Ken-ichi
• Author Heading: Tabei, Ken-ichi
• Publication, Distribution, etc.: 三重大学
• Publication Date: 2019-03-25
• Publication Date (W3CDTF): 2019-03-25
• Degree grantor/type: 三重大学
• Date Granted: 2019-03-25
• Date Granted (W3CDTF): 2019-03-25
• Dissertation Number: 甲医学第1935号
• Degree Type: 博士(医学)
• Conferring No. (Dissertation): 甲医学第1935号
• Text Language Code: eng
• Alias of Author: タベイ, ケンイチ; 田部井, 賢一
• Subject Heading: dementia; exercise with music; cognitive dysfunction; voxel-based morphometry; atrophy; frontal lobe
• Target Audience: 一般
• Note (General): application/pdf; We aimed to determine whether neuropsychological deficits and brain atrophy could predict the efficacy of non-pharmacological interventions. Forty-six participants with mild-to-moderate dementia were monitored for 6 months; 25 underwent an intervention involving physical exercise with music, and 21 performed cognitive stimulation tasks. Participants were categorized into improvement (IMP) and no-IMP subgroups. In the exercise-with-music group, the no-IMP subgroup performed worse than the IMP subgroup on the Rivermead Behavioural Memory Test at baseline. In the cognitivestimulation group, the no-IMP subgroup performed worse than the IMP subgroup on Raven’s Colored Progressive Matrices and the cognitive functional independence measure at baseline. In the no-IMP subgroup, voxel-based morphometric analysis at baseline revealed more extensive gray matter loss in the anterior cingulate gyrus and left middle frontal gyrus in the exercise-with-music and cognitive-stimulation groups, respectively. Participants with mild-to-moderate dementia with cognitive decline and extensive cortical atrophy are less likely to show improved cognitive function after non-pharmaceutical therapy.; 本文/Department of Dementia Prevention and Therapeutics, Graduate School of Medicine, Mie University, Tsu, Japan; 7p
• DOI: info:doi/10.3389/fnagi.2018.00087; https://doi.org/info:doi/10.3389/fnagi.2018.00087
• Persistent ID (NDL): info:ndljp/pid/11378279; https://dl.ndl.go.jp/pid/11378279
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2019-11-04T14:30:53+09:00
• Date Created (W3CDTF): 2019-10-16
• Format (IMT): application/pdf
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Periodical Title (URI): http://hdl.handle.net/10076/00018401; https://mie-u.repo.nii.ac.jp/records/12782
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp

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2023-12-15 再収集