流体力学解析を用いた閉塞性睡眠時無呼吸の上気道通気状態に対する口腔内装置の治療効果に関する研究

• Material Type: 博士論文
• Title: 流体力学解析を用いた閉塞性睡眠時無呼吸の上気道通気状態に対する口腔内装置の治療効果に関する研究
• Author/Editor: 菅, 北斗
• Author Heading: 菅, 北斗
• Publication, Distribution, etc.: Taylor & Francis Group
• Publication Date: 2019
• Publication Date (W3CDTF): 2019
• Alternative Title: Evaluation of the effect of oral appliance treatment on upper-airway ventilation conditions in obstructive sleep apnea using computational fluid dynamics
• Periodical title: THE JOURNAL OF CRANIOMANDIBULAR & SLEEP PRACTICE
• Degree grantor/type: 鹿児島大学
• Date Granted: 2019-09-17
• Date Granted (W3CDTF): 2019-09-17
• Dissertation Number: 乙総論第38号
• Degree Type: 博士(歯学); Doctor of Philosophy in Dental Science
• Conferring No. (Dissertation): 乙総論第38号
• Text Language Code: eng
• Subject Heading: Airway obstruction; computational fluid dynamics; computed tomography; obstructive; oral appliance; polysomnography; respiration; sleep apnea
• NDC: 490
• Target Audience: 一般
• Note (General): 博士論文全文, 博士論文要旨, 最終試験結果の要旨, 論文審査の要旨; Objective: To evaluate the effect of oral appliance (OA) treatment on upper-airway ventilation conditions in patients with obstructive sleep apnea (OSA) using computational fluid dynamics (CFD).Methods: Fifteen patients received OA treatment and underwent polysomnography (PSG) and computed tomography (CT). CT data were used to reconstruct three-dimensional models of nasal and pharyngeal airways. Airflow velocity and airway pressure measurements at inspiration were simulated using CFD.Results: The apnea–hypopnea index (AHI) improved from 23.1 to 10.1 events/h after OA treatment. On CFD analysis, airflow velocity decreased at the retropalatal and epiglottis-tip levels, while airway pressure decreased at the retropalatal, uvular- and epiglottis-tip levels. The AHI of patients with OSA before OA treatment was correlated with airway pressure at the epiglottis-tip level.Discussion: Treatment with OA improved the ventilation conditions of the pharyngeal airway and AHI. Results of CFD analysis of airway pressure and airflow velocity helped determine the severity and ventilatory impairment site of OSA, respectively.Hokuto Suga, Tomonori Iwasaki, Katsuaki Mishima, Hiroyuki Nakano, Yoshiya Ueyama and Youichi YamasakiEvaluation of the effect of oral appliance treatment on upper-airway ventilation conditions in obstructive sleep apnea using computational fluid dynamicsCRANIO®: THE JOURNAL OF CRANIOMANDIBULAR & SLEEP PRACTICE 2019https://doi.org/10.1080/08869634.2019.1596554
• DOI: info:doi/10.1080/08869634.2019.1596554; https://doi.org/info:doi/10.1080/08869634.2019.1596554
• Persistent ID (NDL): info:ndljp/pid/11458159; https://dl.ndl.go.jp/pid/11458159
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2020-03-11T23:38:06+09:00
• Date Created (W3CDTF): 2019-10-08
• Format (IMT): PDF; application/pdf
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Periodical Title (URI): http://hdl.handle.net/10232/00030803
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp

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