Optimal Position of Inferior Vena Cava Cannula in Pediatric Cardiac Surgery : A Prospective, Randomized, Controlled, Double-Blind Study

• Material Type: 博士論文
• Title: Optimal Position of Inferior Vena Cava Cannula in Pediatric Cardiac Surgery : A Prospective, Randomized, Controlled, Double-Blind Study
• Author/Editor: Seino, Yutaka
• Publication, Distribution, etc.: 新潟大学
• Publication Date: 2019-03-25
• Publication Date (W3CDTF): 2019-03-25
• Alternative Title: Optimal Position of Inferior Vena Cava Cannula in Pediatric Cardiac Surgery : A Prospective, Randomized, Controlled, Double-Blind Study; 小児心臓手術における下大静脈脱血カニューレの至適位置に関する研究 : 前向き無作為化二重盲検比較試験
• Degree grantor/type: 新潟大学
• Date Granted: 2019-03-25
• Date Granted (W3CDTF): 2019-03-25
• Dissertation Number: 甲第4558号
• Degree Type: 博士（医学）
• Conferring No. (Dissertation): 甲第4558号
• Text Language Code: eng
• Note (General): Objective: To examine the authors’ hypothesis that during the cardiopulmonary bypass (CPB) in children, the inferior vena cava cannula tip placed proximal to the right hepatic vein orifice would produce a higher venous drainage compared with that placed distally.Design: A prospective, randomized, controlled, double-blind study.Setting: Single university hospital.Participants: Thirty-two patients aged <6 years, scheduled for elective cardiac surgery using CPB for congenital heart disease.Interventions: Participants were randomized to 2 groups: the proximal group with the cannula tip placed proximally within 1 cm of the right hepatic vein orifice and the distal group with the cannula placed distally within 1 cm of the right hepatic vein orifice.Measurements and Main Results: The primary outcome of this study was the perfusion flow rate at the time of establishment of total CPB with cardioplegia. The authors initially planned to enroll 60 patients, but before reaching the target sample size, the authors terminated this study owing to patient safety, and 18 patients in the proximal group and 14 patients in the distal group finally were analyzed. No significant differences in patient characteristics were observed between the 2 groups. The mean perfusion flow rate in the proximal group was significantly greater (2.55 ± 0.27 L/min/m^2) than that in the distal group (2.37 ± 0.20 L/min/m^2, p = 0.04).Conclusion: The inferior vena cava cannula tip placed in the proximal position was clinically superior, compared with a distal placement, in producing higher perfusion flow in children.; 学位の種類: 博士（医学）. 報告番号: 甲第4558号. 学位記番号: 新大院博（医）甲第880号. 学位授与年月日: 平成31年3月25日; 新大院博（医）甲第880号; 元資料の権利情報 : 【○!C】2018 Elsevier Inc. All rights reserved.
• Persistent ID (NDL): info:ndljp/pid/11498328; https://dl.ndl.go.jp/pid/11498328
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• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2020-06-07T00:39:19+09:00
• Date Created (W3CDTF): 2019-09-10
• Format (IMT): application/pdf
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• Periodical Title (URI): http://hdl.handle.net/10191/51305
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp