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FLT3-ITD activates RSK1 to enhance proliferation and survival of AML cells by activating mTORC1 and eIF4B cooperatively with PIM or PI3K and by inhibiting Bad and BIM
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国立国会図書館デジタルコレクション
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DOI[10.3390/cancers11121827]to the data of the same series
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- Material Type
- 博士論文
- Author/Editor
- 渡邉, 大介
- Publication, Distribution, etc.
- Publication Date
- 2020
- Publication Date (W3CDTF)
- 2020
- Alternative Title
- FLT3-ITDはRSK1を活性化し、PIMやPI3Kとの協調的なmTORC1とeIF4Bの活性化やBadとBIMの阻害により、AML細胞の増殖と生存を促進する
- Degree grantor/type
- 東京医科歯科大学
- Date Granted
- 2020-03-26
- Date Granted (W3CDTF)
- 2020-03-26