Nasal high flow improves ventilation during propofol sedation: A randomized cross-over study in healthy volunteers

• Material Type: 博士論文
• ISSN: 1569-9048
• Title: Nasal high flow improves ventilation during propofol sedation: A randomized cross-over study in healthy volunteers
• Volume: 277
• Author/Editor: 三島, 岳
• Author Heading: 三島, 岳
• Publication, Distribution, etc.: Elsevier B.V.
• Publication Date: 2020-06-03
• Publication Date (W3CDTF): 2020-06-03
• Alternative Title: ネーザルハイフローはプロポフォール鎮静中の換気を改善する健康被験者でのランダム化クロスオーバー研究
• Periodical title: Respiratory Physiology & Neurobiology
• Degree grantor/type: Nagasaki University (長崎大学)
• Date Granted: 2020-06-03
• Date Granted (W3CDTF): 2020-06-03
• Dissertation Number: 甲医歯薬第1256号
• Degree Type: 博士(歯学)
• Conferring No. (Dissertation): 甲医歯薬第1256号
• Text Language Code: eng
• Subject Heading: Sedation; Nasal high flow; Ventilation; Propofol; Carbon dioxide
• Target Audience: 一般
• Note (General): Objective: Hypoventilation and carbon dioxide (CO2) retention are common during sedation. The current study investigated the ventilation responses to nasal high flow (NHF) during sedation with propofol. Methods: NHF of 30?L/min and 60?L/min with room air was applied during wakefulness and sedation in 10 male volunteers. Ventilation was monitored by respiratory inductance plethysmography, transcutaneous partial pressure of CO2 (TcCO2), and SpO2. Results: During sedation, NHF of 30?L/min and 60?L/min reduced the TcCO2 by 2.9?±?2.7?mmHg (p = 0.025) and by 3.6?±?3.4?mmHg (p = 0.024) without affecting SpO2 and reduced the mean respiratory rate by 3?±?3 breaths/min (p = 0.011) and by 4?±?3 breaths/min (p = 0.003), respectively. Conclusion: During sedation with propofol, NHF without supplemental oxygen attenuated CO2 retention and reduced the respiratory rate. The findings show that NHF can improve ventilation during sedation, which may reduce the risk of complications related to hypoventilation.; 長崎大学学位論文 学位記番号:博(医歯薬)甲第1256号 学位授与年月日:令和2年6月3日; Author: Gaku Mishima, Takuro Sanuki, James Revie, Max Pinkham, Toshihiro Watanabe, Shinji Kurata, Stanislav Tatkov, Takao Ayuse; Citation: Respiratory Physiology & Neurobiology, 277, 103429; 2020; identifier:Nagasaki University (長崎大学), 博士(歯学) (2020-06-03); http://hdl.handle.net/10069/40083
• DOI: info:doi/10.1016/j.resp.2020.103429; https://doi.org/info:doi/10.1016/j.resp.2020.103429
• Persistent ID (NDL): info:ndljp/pid/11512059; https://dl.ndl.go.jp/pid/11512059
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2020-07-06T20:31:19+09:00
• Date Created (W3CDTF): 2020-12-18
• Format (IMT): PDF
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Related Material (URI): http://hdl.handle.net/10069/40083
• Periodical Title (URI): http://hdl.handle.net/10069/40031
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp

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2021-03-07 再収集