Quantitative Emphysema Measurement On Ultra-High-Resolution CT Scans

• Material Type: 博士論文
• ISSN: 1178-2005
• Title: Quantitative Emphysema Measurement On Ultra-High-Resolution CT Scans
• Volume: 14
• Author/Editor: Xu, Yanyan; 徐, 妍妍
• Author Heading: Xu, Yanyan; 徐, 妍妍
• Publication, Distribution, etc.: University of the Ryukyus
• Publication Date: 2019-10-08
• Publication Date (W3CDTF): 2019-10-08
• Periodical title: International Journal of Chronic Obstructive Pulmonary Disease
• Degree grantor/type: 琉球大学
• Date Granted: 2020-01-29
• Date Granted (W3CDTF): 2020-01-29
• Dissertation Number: 乙第227号
• Degree Type: 博士(医学)
• Conferring No. (Dissertation): 医論第227号
• Text Language Code: eng
• Subject Heading: chronic obstructive pulmonary disease; computed tomography; emphysema; ultra-high-resolution CT; quantitative measurement
• Target Audience: 一般
• Note (General): Purpose: To evaluate the advantages of ultra-high-resolution computed tomography (U-HRCT) scans for the quantitative measurement of emphysematous lesions over conventional HRCTscans. Materials and methods: This study included 32 smokers under routine clinical care who underwent chest CT performed by a U-HRCT scanner. Chronic obstructive pulmonary disease (COPD) was diagnosed in 13 of the 32 participants. Scan data were reconstructed by 2 different protocols: i) U-HRCT mode with a 1024×1024 matrix and 0.25-mm slice thickness and ii) conventional HRCT mode with a 512×512 matrix and 0.5-mm slice thickness. On both types of scans, lesions of emphysema were quantitatively assessed as percentage of low attenuation volume (LAV%, <−950 Hounsfield units). LAV% values determined for scan data from the U-HRCT and conventional HRCT modes were compared by the Wilcoxon matched-pairs signed rank test. The association between LAV% and forced expiratory volume in 1 s per forced vital capacity (FEV_1/FVC) was assessed by the Spearman rank correlation test. Results: Mean values for LAV% determined for the U-HRCT and conventional HRCT modes were 8.9 ± 8.8% and 7.3 ± 8.4%, respectively (P<0.0001). The correlation coefficients for LAV% and FEV_1/FVC on the U-HRCT and conventional HRCT modes were 0.50 and 0.49, respectively (both P<0.01). Conclusion: Compared with conventional HRCT scans, U-HRCT scans reveal emphysematous lesions in greater detail, and provide slightly increased correlation with airflow limitation.; 学位論文
• DOI: info:doi/10.2147/COPD.S223605; https://doi.org/info:doi/10.2147/COPD.S223605
• Persistent ID (NDL): info:ndljp/pid/11551855; https://dl.ndl.go.jp/pid/11551855
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2020-10-06T21:18:06+09:00
• Format (IMT): application/pdf
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Periodical Title (URI): http://hdl.handle.net/20.500.12000/46665; https://u-ryukyu.repo.nii.ac.jp/records/2012587
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp

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