Cortical microinfarcts detected by 3-tesla magnetic resonance imaging : Differentiation between cerebral amyloid angiopathy and embolism

• Material Type: 博士論文
• Title: Cortical microinfarcts detected by 3-tesla magnetic resonance imaging : Differentiation between cerebral amyloid angiopathy and embolism
• Author/Editor: Ishikawa, Hidehiro
• Author Heading: Ishikawa, Hidehiro
• Publication, Distribution, etc.: 三重大学
• Publication Date: 2020-03-25
• Publication Date (W3CDTF): 2020-03-25
• Degree grantor/type: 三重大学
• Date Granted: 2020-03-25
• Date Granted (W3CDTF): 2020-03-25
• Dissertation Number: 甲医学第1998号
• Degree Type: 博士(医学)
• Conferring No. (Dissertation): 甲医学第1998号
• Text Language Code: eng
• Alias of Author: イシカワ, ヒデヒロ; 石川, 英洋
• Target Audience: 一般
• Note (General): application/pdf; Background and Purpose: Cortical microinfarcts (CMIs) are small ischemic lesions found in cerebral amyloid angiopathy (CAA) and embolic stroke. This study aimed to differentiate CMIs caused by CAA from those caused by microembolisms, using 3-tesla magnetic resonance imaging.Methods: We retrospectively investigated 70 patients with at least 1 cortical infarct <10 mm on 3D double inversion recovery imaging. Of the 70 patients, 43 had an embolic stroke history (Emboli-G) while 27 had CAA (CAA-G). We compared the size, number, location, and distribution of CMIs between groups and designed a radiological score for differentiation based on the comparisons.Results: CAA-G showed significantly more lesions <5 mm, which were restricted to the cortex (p<0.01). Cortical lesion number was significantly higher in Emboli-G than in CAA-G (4 vs 2; p<0.01). Lesions in CAA-G and Emboli-G were disproportionately located in the occipital lobe (p<0.01) and frontal or parietal lobe (p=0.04), respectively. In radiological scoring, ≥3 points strongly predicted microembolism (sensitivity, 63%; specificity, 92%) or CAA (sensitivity, 63%; specificity, 91%). The areas under the receiver operating characteristic curve were 0.85 and 0.87 for microembolism and CAA, respectively.Conclusions: Characteristics of CMIs on 3T-MRI may differentiate CMIs due to CAA from those due to microembolisms.; 本文/Department of Neurology, Mie University Hospital; 22p
• Persistent ID (NDL): info:ndljp/pid/11552105; https://dl.ndl.go.jp/pid/11552105
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2020-10-06T21:18:06+09:00
• Date Created (W3CDTF): 2020-09-28
• Format (IMT): application/pdf
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Periodical Title (URI): http://hdl.handle.net/10076/00019155; https://mie-u.repo.nii.ac.jp/records/13537
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp

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2023-12-09 再収集