Hydrocortisone administration was associated with improved survival in Japanese patients with cardiac arrest

• Material Type: 博士論文
• ISSN: 2045-2322
• Title: Hydrocortisone administration was associated with improved survival in Japanese patients with cardiac arrest
• Volume: 7
• Author/Editor: Niimura, Takahiro; Zamami, Yoshito; Koyama, Toshihiro; Izawa-Ishizawa, Yuki; Miyake, Masashi; Koga, Tadashi; Harada, Keisaku; Ohshima, Ayako; Imai, Toru; Kondo, Yutaka; Imanishi, Masaki; Takechi, Kenshi; Fukushima, Keijo; Horinouchi, Yuya; Ikeda, Yasumasa; Fujino, Hiromichi; Tsuchiya, Koichiro; Tamaki, Toshiaki; Hinotsu, Shiro; Kano, Mitsunobu R.; Ishizawa, Keisuke
• Author Heading: Niimura, Takahiro; Zamami, Yoshito; Koyama, Toshihiro; Izawa-Ishizawa, Yuki; Miyake, Masashi; Koga, Tadashi; Harada, Keisaku; Ohshima, Ayako; Imai, Toru; Kondo, Yutaka; Imanishi, Masaki; Takechi, Kenshi; Fukushima, Keijo; Horinouchi, Yuya; Ikeda, Yasumasa; Fujino, Hiromichi; Tsuchiya, Koichiro; Tamaki, Toshiaki; Hinotsu, Shiro; Kano, Mitsunobu R.; Ishizawa, Keisuke
• Publication, Distribution, etc.: Springer Nature
• Publication Date: 2017-12-20
• Publication Date (W3CDTF): 2017-12-20
• Alternative Title: ヒドロコルチゾン投与は日本人心肺停止患者の生存率改善に関連する
• Periodical title: Scientific Reports
• Degree grantor/type: 徳島大学
• Date Granted: 2021-03-23
• Date Granted (W3CDTF): 2021-03-23
• Dissertation Number: 甲第3502号
• Degree Type: 博士（医学）
• Conferring No. (Dissertation): 甲第3502号
• Text Language Code: eng
• Subject Heading: Hydrocortisone; Cardiac arrest; Database
• Target Audience: 一般
• Note (General): There are few reports on hydrocortisone administration after cardiac arrest, and those that have been published included few subjects. This study aimed to evaluate the effect of hydrocortisone administration on the outcomes of patients who experienced cardiac arrest. We investigated the survival discharge rates and the length of hospital stay from cardiac arrest to discharge, stratified by use of hydrocortisone, using a Japanese health-insurance claims dataset that covers approximately 2% of the Japanese population. The study included the data of 2233 subjects who experienced either in-hospital or out-of-hospital cardiac arrest between January 2005 and May 2014. These patients were divided into two groups, based on the administration of hydrocortisone. We adjusted the baseline characteristics, medical treatment, and drug administration data of the two groups using propensity scores obtained via the inverse probability of treatment weighted method. The hydrocortisone group had a significantly higher survival discharge rate (13/61 [21.1%] vs. 240/2172 [11.0%], adjusted odds ratio: 4.2, 95% CI: 1.60–10.98, p = 0.004). In addition, the administration of hydrocortisone was independent predictor of survival to discharge (hazard ratio: 4.6, p < 0.001). The results demonstrate a correlation between hydrocortisone administration and the high rates of survival to discharge.
• DOI: info:doi/10.1038/s41598-017-17686-3; https://doi.org/info:doi/10.1038/s41598-017-17686-3
• Persistent ID (NDL): info:ndljp/pid/11671531; https://dl.ndl.go.jp/pid/11671531
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2021-05-16T23:51:55+09:00
• Format (IMT): application/pdf; application/msword
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Periodical Title (URI): http://repo.lib.tokushima-u.ac.jp/112397
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp