Pulmonary Artery Wall Thickness Assessed by Optical Coherence Tomography Correlates With Pulmonary Hemodynamics in Children With Congenital Heart Disease

• Material Type: 博士論文
• ISSN: 1346-9843
• Title: Pulmonary Artery Wall Thickness Assessed by Optical Coherence Tomography Correlates With Pulmonary Hemodynamics in Children With Congenital Heart Disease
• Volume: 82 9
• Author/Editor: Homma, Yukako; Hayabuchi, Yasunobu; Ono, Akemi; Kagami, Shoji
• Author Heading: Homma, Yukako; Hayabuchi, Yasunobu; Ono, Akemi; Kagami, Shoji
• Publication, Distribution, etc.: The Japanese Circulation Society
• Publication Date: 2018-08-24
• Publication Date (W3CDTF): 2018-08-24
• Alternative Title: 先天性心疾患の小児における光干渉断層撮影法を用いた肺動脈壁厚と肺循環動態の関連についての検討; PA Thickening on OCT in Children With CHD
• Periodical title: Circulation Journal
• Degree grantor/type: 徳島大学
• Date Granted: 2021-03-23
• Date Granted (W3CDTF): 2021-03-23
• Dissertation Number: 甲第3498号
• Degree Type: 博士（医学）
• Conferring No. (Dissertation): 甲第3498号
• Text Language Code: eng
• Subject Heading: Children; Congenital heart disease; Optical coherence tomography; Pulmonary arterial hypertension
• Target Audience: 一般
• Note (General): Background: Pulmonary arterial (PA) wall thickening evaluated by optical coherence tomography (OCT) has been reported in adults with PA hypertension. The purpose of this study was to evaluate the feasibility of OCT for preoperative assessment of the PA wall in children with congenital heart disease (CHD).Methods and Results: Participants comprised 39 patients with ventricular septal defect, atrial septal defect, or patent ductus arteriosus. Attempts were made to evaluate vessels of various diameters using OCT. Clearly observed vessels that were optimal for evaluation were selected and classified into 4 subgroups by diameter of the lumen. Optimal depiction was obtained in 80 of 156 vessels in total, and 25 (64.1%), 34 (87.1%), 17 (43.6%), and 4 vessels (10.3%) in each of the 1.0–<2.0 mm, 2.0–<3.0 mm, 3.0–<4.0 mm, and 4.0–5.0 mm subgroups, respectively. Arterial walls in the 2.0–<3.0 mm subgroup were the most frequently delineated, and wall thickness correlated significantly with mean PA pressure, pulmonary vascular resistance index, pulmonary-to-systemic flow ratio, and PA capacitance index (r=0.56, 0.52, 0.37, and −0.49, respectively). The 3-layered appearance was delineated in 29 of 80 vessels (36.2%). This feature had no significant correlation with pulmonary hemodynamics.Conclusions: OCT represents a promising tool for evaluating the PA wall in children with CHD.
• DOI: info:doi/10.1253/circj.CJ-18-0379; https://doi.org/info:doi/10.1253/circj.CJ-18-0379
• Persistent ID (NDL): info:ndljp/pid/11671991; https://dl.ndl.go.jp/pid/11671991
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2021-05-16T23:51:55+09:00
• Format (IMT): application/pdf
• Access Restrictions: 国立国会図書館内限定公開
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• Availability of remote photoduplication service: 可
• Periodical Title (URI): http://repo.lib.tokushima-u.ac.jp/113960
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp