Factors related to the occurrence of phlebitis in acute phase stroke patients receiving intravenous nicardipine hydrochloride as antihypertensive therapy 1

• Material Type: 博士論文
• ISSN: 2187-9354
• Title: Factors related to the occurrence of phlebitis in acute phase stroke patients receiving intravenous nicardipine hydrochloride as antihypertensive therapy
• Volume: 6 1
• Author/Editor: Yokoi, Yasuko; Minagawa, Takako; Tamura, Ayako
• Author Heading: Yokoi, Yasuko; Minagawa, Takako; Tamura, Ayako
• Publication, Distribution, etc.: Japanese Academy of Neuroscience Nursing
• Publication Date: 2019-12-31
• Publication Date (W3CDTF): 2019-12-31
• Alternative Title: 降圧療法としてのニカルジピン塩酸塩を使用する脳卒中急性期患者の静脈炎発症の関連要因; Factors related to the occurrence of phlebitis in acute phase stroke patients receiving intravenous nicardipine
• Periodical title: Journal of Japanese Academy of Neuroscience Nursing
• Degree grantor/type: 徳島大学
• Date Granted: 2020-03-23
• Date Granted (W3CDTF): 2020-03-23
• Dissertation Number: 甲第3420号
• Degree Type: 博士（保健学）
• Conferring No. (Dissertation): 甲第3420号
• Text Language Code: eng
• Subject Heading: Stroke; Nicardipine; Phlebitis; Factors
• Target Audience: 一般
• Note (General): This study investigated the incidence of phlebitis associated with continuous nicardipine infusion in patients with acute-phase stroke. To identify patient factors related to the occurrence of phlebitis, and considering blood pressure values during nicardipine administration, we retrospectively investigated the nursing and medical records of 301 patients who were hospitalized for stroke. Of these, 92 patients met the inclusion criteria and had data showing whether phlebitis had occurred. We confirmed that phlebitis occurred in 38 patients (41.3%). Factors found to be significantly related to phlebitis onset were Glasgow Coma Scale (GCS)-verbal (V; p = .020) and -motor (M; p = .007), level of consciousness (total GCS score [(p = .009)]), nicardipine administration time (p = .001), nicardipine dose (p = .000), mean nicardipine rate of administration (p = .000), nicardipine dilution rate (p = .000), mean arterial blood pressure at first insertion (p = .030), and difference in the diastolic blood pressure at first insertion (p = .032). Multiple logistic regression analysis indicated that nicardipine administration time (odds ratio: 1.042, 95% confidence interval: 1.023–1.062, p = .000) was a related factor. Results also suggested that a decreased level of consciousness after the stroke onset (V3 or below and M5 or below) is related to phlebitis occurrence. Patients with stroke having a lower level of consciousness (total GCS score of 12 or below), who are being administered continuous nicardipine infusion, may require more frequent and careful infusion management and needle insertion site observation. Because phlebitis onset occurs after 24 h of continuous infusion, peripheral insertion site catheter replacement should be performed within 24 h.
• Persistent ID (NDL): info:ndljp/pid/11675777; https://dl.ndl.go.jp/pid/11675777
• Collection: 障害者向け資料
• Collection (Materials For Handicapped People:1): テキストデータ
• Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• Acquisition Basis: 博士論文（自動収集）
• Date Accepted (W3CDTF): 2021-05-30T17:29:36+09:00
• Format (IMT): application/pdf
• Access Restrictions: 国立国会図書館内限定公開
• Service for the Digitized Contents Transmission Service: 図書館・個人送信対象外
• Availability of remote photoduplication service: 可
• Periodical Title (URI): http://repo.lib.tokushima-u.ac.jp/114738
• Data Provider (Database): 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp