Effect of low intensity pulsed ultrasound on osteoclast differentiation

Persistent ID (NDL): info:ndljp/pid/12071399

Material type: 博士論文

Author: 東, 友莉

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Publication date: 2021-03-05

Material Format: Digital

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Name of awarding university/degree: 大阪歯科大学,博士（歯学）

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Note (General)：: Purpose: For many years, people have attempted to identify ways of efficiently moving teeth in orthodontic therapy to reduce harmful effects. In this ...

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Material Type: 博士論文
Title: Effect of low intensity pulsed ultrasound on osteoclast differentiation
Author/Editor: 東, 友莉
Author Heading: 東, 友莉
Publication Date: 2021-03-05
Publication Date (W3CDTF): 2021-03-05
Alternative Title: 低出力超音波パルス(LIPUS)照射が破骨細胞分化に対する影響について
Degree grantor/type: 大阪歯科大学
Date Granted: 2021-03-05
Date Granted (W3CDTF): 2021-03-05
Dissertation Number: 甲第898号
Degree Type: 博士（歯学）
Conferring No. (Dissertation): 甲第898号
Text Language Code: eng
Subject Heading: Low-intensity pulsed ultrasound｜osteoclast differentiation｜RAW264 cells｜RANKL｜orthodontic tooth movement
Target Audience: 一般
Note (General): Purpose: For many years, people have attempted to identify ways of efficiently moving teeth in orthodontic therapy to reduce harmful effects. In this study, we investigate whether the non-surgical method of low-intensity pulsed ultrasound (LIPUS) irradiation affects osteoclast differentiation in vitro. Materials and Methods: RAW264 cells were stimulated with RANKL and U0126, and LIPUS irradiation was performed using different ultrasonic outputs, irradiation times, and number of irradiations. Assessments used TRAP staining, TRAP quantitative assays, and western blot analysis. Results: LIPUS irradiation significantly increased osteoclast differentiation rates of RAW264 cells. The rates were significantly higher in the three-time irradiation group compared with the single irradiation group. However, significant differences were not observed between the ultrasonic output. TRAP quantitative assay results showed significantly increased osteoclast differentiation rates with increased irradiation time, however, only in the single irradiation group.Conclusion: These results suggest that an increased number of LIPUS irradiations may improve its effectiveness in orthodontic therapy.
2020年度
Persistent ID (NDL): info:ndljp/pid/12071399
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Collection (particular): 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文
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Acquisition Basis: 博士論文（自動収集）
Date Accepted (W3CDTF): 2022-02-06T04:33:19+09:00
Date Created (W3CDTF): 2021-04-23
Format (IMT): application/pdf
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Periodical Title (URI): http://id.nii.ac.jp/1392/00000265/
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